Is There A Connection Between Primary Hypophysitis and Celiac
Disease?
Conclusion Although patients with PH were found to have significant levels
of HLA-DQ2/8, no CD was found in the tissue. Higher levels of pituitary
antibodies were detected in celiac patients compared with healthy controls, but
no hypophysitis clinic was observed at follow-up. Although these findings
suggest that the two diseases may share a common genetic and autoimmune basis,
the development of the disease may be partially explained by exposure to
environmental factors. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJo...
Source: Experimental and Clinical Endocrinology and Diabetes - January 18, 2024 Category: Endocrinology Authors: Kara, Zehra E şkazan, Tuğçe Şahin, Serdar Durcan, Emre Sulu, Cem Demir, Ahmet Numan Uysal, Serhat Özkaya, Hande Mefkure Y ılmaz, Erkan Hatemi, Ali İbrahim Bolay ırlı, İbrahim Murat Kad ıoğlu, Pınar Tags: Article Source Type: research
Characterisation of T cell receptor repertoires in coeliac disease
Conclusions
Small intestinal TRB and TRG repertoires of patients with CD are more diverse than individuals without CD, likely due to mucosal recruitment and accumulation of T cells because of protracted inflammation. Enrichment of the unique TRG CDR3 AA sequence in the mucosa of patients with CD may suggest disease-associated changes in the TCR IE lymphocyte (IEL) landscape. (Source: Journal of Clinical Pathology)
Source: Journal of Clinical Pathology - January 18, 2024 Category: Pathology Authors: Lee, L. W., Shafiani, S., Crossley, B., Emerson, R. O., Williamson, D., Bunin, A., Vargas, J., Han, A. S., Kaplan, I. M., Green, P. H. R., Kirsch, I., Bhagat, G. Tags: Open access Original research Source Type: research
Randomized Controlled Trials in Celiac Disease: Expressing the Patient ’s Voice
(Source: Gastroenterology)
Source: Gastroenterology - January 17, 2024 Category: Gastroenterology Authors: Debra G. Silberg, Jordan Dubow, Alice Bast Tags: Correspondence Source Type: research
