“The crackers challenge”: A reassuring low-dose gluten challenge in adults on gluten-free diet without proper diagnosis of coeliac disease

Gluten-free diet (GFD) is the one therapy in coeliac disease (CeD). Unfortunately, some patients adopt GFD before the diagnostic work-up. The guidelines suggest a 14-day gluten intake> 3 gr to get CeD diagnosis, although many subjects refuse this approach. Other evidence showed that the intake of 50 mg/day of gluten for 3 months could be useful for CeD diagnosis.

Source: Digestive and Liver Disease - March 23, 2024 Category: Gastroenterology Authors: Antonio Rispo, Alessia Dalila Guarino, Monica Siniscalchi, Nicola Imperatore, Antonella Santonicola, Simona Ricciolino, Roberto de Sire, Benedetta Toro, Nicola Mattia Cantisani, Carolina Ciacci Tags: Alimentary Tract Source Type: research