Anacardium occidentale L. (cajueiro) in the healing of skin wounds: an experimental study in rats
CONCLUSIONS: There was a prolongation of the healing phase of the animals treated with the extract, and the animals in the NCG showed a better outcome by histological analysis.PMID:36629623 | DOI:10.1590/acb371006 (Source: Acta Cirurgica Brasileira)
Source: Acta Cirurgica Brasileira - January 11, 2023 Category: Surgery Authors: Dafni Cleia Gaia da Silva Hanna Machado da Silva Pedro Pastorini Franco Tomaz Jos é Aquino Vasconcelos do Carmo Deivid Ramos Dos Santos Edvaldo Lima Silveira Ana Carla Godinho Pinto Marcieni Ata íde de Andrade Rosa Helena de Figueiredo Chaves Source Type: research
The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome
In this study, the microbial community of the Sorghum bicolor rhizosphere was spiked with technical cashew nut shell liquid, and after incubation, the environmental DNA (eDNA) was extracted and subsequently used to build a metagenomic library. We report the biochemical features and crystal structure of a novel esterase from the family IV, EH0, retrieved from an uncultured sphingomonad after a functional screen in tributyrin agar plates. EH0 (optimum temperature [Topt], 50°C; melting temperature [Tm], 55.7°C; optimum pH [pHopt], 9.5) was stable in the presence of 10 to 20% (vol/vol) organic solvents and exhibited hydrolyt...
Source: Applied and Environmental Microbiology - January 5, 2023 Category: Microbiology Authors: Marco Distaso Isabel Cea-Rama Cristina Coscol ín Tatyana N Chernikova Hai Tran Manuel Ferrer Julia Sanz-Aparicio Peter N Golyshin Source Type: research
The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome
In this study, the microbial community of the Sorghum bicolor rhizosphere was spiked with technical cashew nut shell liquid, and after incubation, the environmental DNA (eDNA) was extracted and subsequently used to build a metagenomic library. We report the biochemical features and crystal structure of a novel esterase from the family IV, EH0, retrieved from an uncultured sphingomonad after a functional screen in tributyrin agar plates. EH0 (optimum temperature [Topt], 50°C; melting temperature [Tm], 55.7°C; optimum pH [pHopt], 9.5) was stable in the presence of 10 to 20% (vol/vol) organic solvents and exhibited hydrolyt...
Source: Applied and Environmental Microbiology - January 5, 2023 Category: Microbiology Authors: Marco Distaso Isabel Cea-Rama Cristina Coscol ín Tatyana N Chernikova Hai Tran Manuel Ferrer Julia Sanz-Aparicio Peter N Golyshin Source Type: research
The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome
In this study, the microbial community of the Sorghum bicolor rhizosphere was spiked with technical cashew nut shell liquid, and after incubation, the environmental DNA (eDNA) was extracted and subsequently used to build a metagenomic library. We report the biochemical features and crystal structure of a novel esterase from the family IV, EH0, retrieved from an uncultured sphingomonad after a functional screen in tributyrin agar plates. EH0 (optimum temperature [Topt], 50°C; melting temperature [Tm], 55.7°C; optimum pH [pHopt], 9.5) was stable in the presence of 10 to 20% (vol/vol) organic solvents and exhibited hydrolyt...
Source: Applied and Environmental Microbiology - January 5, 2023 Category: Microbiology Authors: Marco Distaso Isabel Cea-Rama Cristina Coscol ín Tatyana N Chernikova Hai Tran Manuel Ferrer Julia Sanz-Aparicio Peter N Golyshin Source Type: research
The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome
In this study, the microbial community of the Sorghum bicolor rhizosphere was spiked with technical cashew nut shell liquid, and after incubation, the environmental DNA (eDNA) was extracted and subsequently used to build a metagenomic library. We report the biochemical features and crystal structure of a novel esterase from the family IV, EH0, retrieved from an uncultured sphingomonad after a functional screen in tributyrin agar plates. EH0 (optimum temperature [Topt], 50°C; melting temperature [Tm], 55.7°C; optimum pH [pHopt], 9.5) was stable in the presence of 10 to 20% (vol/vol) organic solvents and exhibited hydrolyt...
Source: Applied and Environmental Microbiology - January 5, 2023 Category: Microbiology Authors: Marco Distaso Isabel Cea-Rama Cristina Coscol ín Tatyana N Chernikova Hai Tran Manuel Ferrer Julia Sanz-Aparicio Peter N Golyshin Source Type: research
Biochemical analysis leads to improved orthogonal bioluminescent tools
Chembiochem. 2023 Jan 2. doi: 10.1002/cbic.202200726. Online ahead of print.ABSTRACTEngineered luciferase-luciferin pairs have expanded the number of cellular targets that can be visualized in tandem. While light production relies on selective processing of synthetic luciferins by mutant luciferases, little is known about the origin of selectivity. The development of new and improved pairs requires a better understanding of the structure-function relationship of bioluminescent probes. In this work, we report a biochemical approach to assessing and optimizing two popular bioluminescent pairs: Cashew/D-luc and Pecan/4'-BrLuc...
Source: Chembiochem - January 2, 2023 Category: Biochemistry Authors: Sierra J Williams Jordan A Gewing-Mullins Whitney K Lieberman Bethany Kolbaba-Kartchner Reema Iqbal Hana M Burgess Clair M Colee Marya Y Ornelas Edison S Reid-McLaughlin Jeremy H Mills Jennifer A Prescher Aaron Morgan Leconte Source Type: research
Biochemical analysis leads to improved orthogonal bioluminescent tools
Chembiochem. 2023 Jan 2. doi: 10.1002/cbic.202200726. Online ahead of print.ABSTRACTEngineered luciferase-luciferin pairs have expanded the number of cellular targets that can be visualized in tandem. While light production relies on selective processing of synthetic luciferins by mutant luciferases, little is known about the origin of selectivity. The development of new and improved pairs requires a better understanding of the structure-function relationship of bioluminescent probes. In this work, we report a biochemical approach to assessing and optimizing two popular bioluminescent pairs: Cashew/D-luc and Pecan/4'-BrLuc...
Source: Chembiochem - January 2, 2023 Category: Biochemistry Authors: Sierra J Williams Jordan A Gewing-Mullins Whitney K Lieberman Bethany Kolbaba-Kartchner Reema Iqbal Hana M Burgess Clair M Colee Marya Y Ornelas Edison S Reid-McLaughlin Jeremy H Mills Jennifer A Prescher Aaron Morgan Leconte Source Type: research
Sensors, Vol. 23, Pages 349: Estimation of Aboveground Biomass in Agroforestry Systems over Three Climatic Regions in West Africa Using Sentinel-1, Sentinel-2, ALOS, and GEDI Data
chael Thiel
Agroforestry systems (AFS) offer viable solutions for climate change because of the aboveground biomass (AGB) that is maintained by the tree component. Therefore, spatially explicit estimation of their AGB is crucial for reporting emission reduction efforts, which can be enabled using remote sensing (RS) data and methods. However, multiple factors including the spatial distributions within the AFS, their structure, their composition, and their variable extents hinder an accurate RS-assisted estimation of the AGB across AFS. The aim of this study is to (i) evaluate the potential of spaceborne optical, SAR an...
Source: Sensors - December 29, 2022 Category: Biotechnology Authors: Dan Kanmegne Tamga Hooman Latifi Tobias Ullmann Roland Baumhauer Jules Bayala Michael Thiel Tags: Article Source Type: research
Molecules, Vol. 27, Pages 8733: Cashew (Anacardium occidentale) Nut-Shell Liquid as Antioxidant in Bulk Soybean Oil
nca
Recently, natural antioxidants for the food industry have become an important focus. Cashew nut-shell liquid (CNSL) is composed of compounds that can act as natural antioxidants in food systems. The aim of this work was to evaluate the potential of CNSL and its components to act as natural antioxidants in a bulk oil system. CNSL was treated with calcium hydroxide to obtain two fractions [cardol/cardanols acid fraction (CCF) and anacardic acid fraction (AF)]. CNSL, FF and AF were analyzed by thin-layer chromatography and Fourier-transform infrared spectroscopy. The protective effects of CNSL, CCF and AF were tested ...
Source: Molecules - December 9, 2022 Category: Chemistry Authors: Sandra-Yaneth Gait án-Jiménez Luz-Patricia Restrepo-S ánchez Fabi án Parada-Alfonso Carlos-Eduardo Narv áez-Cuenca Tags: Article Source Type: research
Anacardium occidentale leaves extract and riboceine mitigate hyperglycemia through anti-oxidative effects and modulation of some selected genes associated with diabetes
ConclusionThe results obtained in this study demonstrate significant antidiabetic properties of ethanolic extract ofA. occidentale and riboceine. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - December 8, 2022 Category: Endocrinology Source Type: research
Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol
This study aimed to evaluate antileishmanial, cytotoxic and immunomodulatory activities of CNSL and CN. Both showed antileishmanial potential, with IC50 for CNSL and CN against Leishmania infantum: 148.12 and 56.74 μg/mL; against Leishmania braziliensis: 85.71 and 64.28 μg/ml; against Leishmania major: 153.56 and 122.31 μg/mL, respectively. The mean cytotoxic concentrations (CC50) of CNSL and CN were 37.51 and 31.44 μg/mL, respectively. CNSL and CN significantly reduced the percentage of infected macrophages, with a selectivity index (SI) >20 for CN. CNSL and cardanol caused an increase in phagocytic capacity and ly...
Source: Toxicology in Vitro - November 26, 2022 Category: Toxicology Authors: Iuliana Marjory Martins Ribeiro Val éria Carlos de Sousa Evellyn Caroline Silva Melo Rita de C ássia Viana de Carvalho Maisa de Sousa Dos Santos Jos é Arimatéia de Oliveira Nery Neto Danielly Silva de Melo Let ícia Soares de Araújo Teixeira Ant ôni Source Type: research
Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol
This study aimed to evaluate antileishmanial, cytotoxic and immunomodulatory activities of CNSL and CN. Both showed antileishmanial potential, with IC50 for CNSL and CN against Leishmania infantum: 148.12 and 56.74 μg/mL; against Leishmania braziliensis: 85.71 and 64.28 μg/mL; against Leishmania major: 153.56 and 122.31 μg/mL, respectively. The mean cytotoxic concentrations (CC50) of CNSL and CN were 37.51 and 31.44 μg/mL, respectively. CNSL and CN significantly reduced the percentage of infected macrophages, with a selectivity index (SI) >20 for CN. CNSL and cardanol caused an increase in phagocytic capacity and ly...
Source: Toxicology in Vitro - November 26, 2022 Category: Toxicology Authors: Iuliana Marjory Martins Ribeiro Val éria Carlos de Sousa Evellyn Caroline Silva Melo Rita de C ássia Viana de Carvalho Maisa de Sousa Dos Santos Jos é Arimatéia de Oliveira Nery Neto Danielly Silva de Melo Let ícia Soares de Araújo Teixeira Ant ôni Source Type: research
Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol
This study aimed to evaluate antileishmanial, cytotoxic and immunomodulatory activities of CNSL and CN. Both showed antileishmanial potential, with IC50 for CNSL and CN against Leishmania infantum: 148.12 and 56.74 μg/mL; against Leishmania braziliensis: 85.71 and 64.28 μg/mL; against Leishmania major: 153.56 and 122.31 μg/mL, respectively. The mean cytotoxic concentrations (CC50) of CNSL and CN were 37.51 and 31.44 μg/mL, respectively. CNSL and CN significantly reduced the percentage of infected macrophages, with a selectivity index (SI) >20 for CN. CNSL and cardanol caused an increase in phagocytic capacity and ly...
Source: Toxicology in Vitro - November 26, 2022 Category: Toxicology Authors: Iuliana Marjory Martins Ribeiro Val éria Carlos de Sousa Evellyn Caroline Silva Melo Rita de C ássia Viana de Carvalho Maisa de Sousa Dos Santos Jos é Arimatéia de Oliveira Nery Neto Danielly Silva de Melo Let ícia Soares de Araújo Teixeira Ant ôni Source Type: research
Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol
Toxicol In Vitro. 2022 Nov 23;87:105524. doi: 10.1016/j.tiv.2022.105524. Online ahead of print.NO ABSTRACTPMID:36435415 | DOI:10.1016/j.tiv.2022.105524 (Source: Toxicology in Vitro)
Source: Toxicology in Vitro - November 26, 2022 Category: Toxicology Authors: Iuliana Marjory Martins Ribeiro Val éria Carlos de Sousa Evellyn Caroline Silva Melo Rita de C ássia Viana de Carvalho Maisa de Sousa Dos Santos Jos é Arimatéia de Oliveira Nery Neto Danielly Silva de Melo Let ícia Soares de Araújo Teixeira Ant ôni Source Type: research
Antileishmania and immunomodulatory potential of cashew nut shell liquid and cardanol
This study aimed to evaluate antileishmanial, cytotoxic and immunomodulatory activities of CNSL and CN. Both showed antileishmanial potential, with IC50 for CNSL and CN against Leishmania infantum: 148.12 and 56.74 μg/mL; against Leishmania braziliensis: 85.71 and 64.28 μg/ml; against Leishmania major: 153.56 and 122.31 μg/mL, respectively. The mean cytotoxic concentrations (CC50) of CNSL and CN were 37.51 and 31.44 μg/mL, respectively. CNSL and CN significantly reduced the percentage of infected macrophages, with a selectivity index (SI) >20 for CN. CNSL and cardanol caused an increase in phagocytic capacity and ly...
Source: Toxicology in Vitro - November 26, 2022 Category: Toxicology Authors: Iuliana Marjory Martins Ribeiro Val éria Carlos de Sousa Evellyn Caroline Silva Melo Rita de C ássia Viana de Carvalho Maisa de Sousa Dos Santos Jos é Arimatéia de Oliveira Nery Neto Danielly Silva de Melo Let ícia Soares de Araújo Teixeira Ant ôni Source Type: research
