Smart Stent Monitors Hemodynamics
Researchers at the Georgia Institute of Technology have developed a smart stent that can monitor hemodynamic parameters. The wireless and battery-free device can transmit the data to the outside of the body, and is powered through a wireless energy transfer system that uses magnetic fields, similar to wireless chargers that are available for many smartphones. The system could be helpful in long-term monitoring and aid patients with cardiovascular issues to avoid repeated angiograms. It can also potentially function as an early warning alarm for issues such as changes in blood pressure. Stents are invaluable in treating ...
Source: Medgadget - May 18, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Cardiology Radiology Vascular Surgery Source Type: blogs

One Rational Expectation For Each: The Next Healthcare Moves Of Tech Giants
Walmart announced the opening of five new ‘Walmart Health’ Centres in Florida in April, promising low-cost healthcare services. Not very surprising given how the American firm has been steadily building a foothold in this industry in recent years without any signs of slowing down.  In the U.S., Walmart established 600 COVID-19 testing sites during the pandemic; before the current announcement, Walmart Health business has rolled out in 20 locations across Arkansas, Georgia and Illinois in the last three years complete with primary care, emergency care, labs and more. By 2029, Walmart’s board even plans to scal...
Source: The Medical Futurist - April 14, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Forecast Future of Medicine digital health Healthcare tech giants Source Type: blogs

From Surgeries To Keeping Company: The Place Of Robots In Healthcare
Assisting surgeries, disinfecting rooms, dispensing medication, keeping company: believe it or not these are the tasks medical robots will soon undertake in hospitals, pharmacies, or your nearest doctor’s office. These new ‘colleagues’ will definitely make a difference in every field of medicine. Here’s our overview to understand robotics in healthcare better so that everyone can prepare for the appearance of mechanic helpers in medical facilities. Metallic allies for the benefit of the vulnerable While there are concerns for machines replacing people in the workforce, we believe there are adv...
Source: The Medical Futurist - April 11, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Future of Pharma Robotics digital health Healthcare Hospital medical nanotechnology Surgery pharmacies future of hospital blood telemedicine social companion social companion robot telemedical medical rob Source Type: blogs

Fight Aging! Newsletter, April 11th 2022
In conclusion, plasma levels of IGHA2, APOA and HPT are associated with subclinical atherosclerosis independently of traditional risk factors and offers potential to predict this disease. The panel could improve primary prevention strategies in areas where imaging is not available. A Lesser Diversity of Circulating Antibodies in the Aging Killifish Immune System https://www.fightaging.org/archives/2022/04/a-lesser-diversity-of-circulating-antibodies-in-the-aging-killifish-immune-system/ Short-lived killifish are one of the more recently adopted animal models of aging. All such models are a trade-off bet...
Source: Fight Aging! - April 10, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

If You ’ ve Seen One Robot – Wait, What?
BY KIM BELLARD If You’ve Seen One Robot – Wait, What? We think we know robots, from the old school Robbie the Robot to the beloved R2-D2/C-3PO to the acrobatic Boston Dynamics robots or the very human-like Westworld ones.   But you have to love those scientists: they keep coming up with new versions, ones that shatter our preconceptions.  Two, in particular, caught my attention, in part because both expect to have health care applications, and in part because of how they’re described. Hint: the marketing people are going to have some work to do on the names.  ———– Let’s...
Source: The Health Care Blog - April 7, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Health Tech Kim Bellard robots SlimeBot Source Type: blogs

vMap Mapping Technology for Cardiac Arrhythmias: Interview with Mike Monko, CEO of Vektor Medical
Vektor Medical, a medtech company based in San Diego, created the vMap system, a mapping solution for cardiac arrhythmias. The system is the first to identify arrhythmia sources anywhere in the heart, including the septal wall, outflow tracts, and all four chambers. The company reports that the technology takes less than three minutes to provide a result. The system uses 12-lead electrocardiogram (ECG) data to pin-point the location of an arrythmia, and so is non-invasive. Accurate mapping of arrythmia sources is important in ensuring that subsequent treatment is successful. In the case of ablation for atrial fibrillati...
Source: Medgadget - April 4, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Cardiac Surgery Cardiology Exclusive Radiology afib vektormedical Source Type: blogs

Fight Aging! Newsletter, March 14th 2022
This study tests the feasibility of chronically elevating skeletal muscle NAD+ in mice and investigates the putative effects on mitochondrial respiratory capacity, insulin sensitivity, and gene expression. The metabolic effects of NR and PT treatment were modest. We conclude that the chronic elevation of skeletal muscle NAD+ by the intravenous injection of NR is possible but does not affect muscle respiratory capacity or insulin sensitivity in either sedentary or physically active mice. Our data have implications for NAD+ precursor supplementation regimens. Muscle Strengthening Activities in Later Life Correlate ...
Source: Fight Aging! - March 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, February 28th 2022
In conclusion, as BMI and waist circumference are related to elevations of immune markers in the IL-6 pathway, chronic inflammation might be an important mediator of the relationship between BMI and frailty. Fat Tissue Becomes Dysfunctional with Age as Mitochondria Falter https://www.fightaging.org/archives/2022/02/fat-tissue-becomes-dysfunctional-with-age-as-mitochondria-falter/ Mitochondria are effectively power plants, hundreds of them working in every cell to produce chemical energy store molecules to power cellular processes. Mitochondrial function declines with age, unfortunately, for underlying r...
Source: Fight Aging! - February 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, February 14th 2022
In conclusion, this first examination of the effects of age and the ageing process on the small intestinal microbiome demonstrates that the duodenal microbiome changes with increasing age, with significant decreases in duodenal microbial diversity due to increased prevalence of phylum Proteobacteria, particularly coliforms and anaerobic taxa. Given the key roles of small intestinal microbes in nutrient absorption and host metabolism, these changes may be clinically relevant for human health during the ageing process. Naked Mole Rats Exhibit Minimal Cardiac Aging https://www.fightaging.org/archives/2022/02/nake...
Source: Fight Aging! - February 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Further Evidence for Cellular Senescence to Contribute to Atrial Fibrillation
Senescent cells accumulate with age, and their secretions provoke chronic inflammation and tissue dysfunction. With this in mind, researchers have shown that cellular senescence correlates with atrial fibrillation in older people. Here is a more recent demonstration of this relationship. I'm not aware of a study that shows senolytic therapy to remove senescent cells is a useful treatment for atrial fibrillation, but evaluation of this approach seems a good idea, both in aged animal models and in human patients. Atrial fibrillation (AF) is the most frequent arrhythmia in clinical practice and is closely associated ...
Source: Fight Aging! - February 11, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, January 3rd 2022
In this study, we showed that the iPaD (inducing Plagl2 and anti-Dyrk1a) lentivirus substantially rejuvenated the proliferative and neurogenic potential of NSCs in the aged brain. Clonal analysis by a sparse labeling approach as well as transcriptome analysis indicated that iPaD can rejuvenate aged NSCs (19-21 mo of age) to a level comparable with those at 1 or 2 months of age and successfully improved cognition of aged mice. Once rejuvenated and activated by iPaD, aged dormant NSCs can generate, on average, 4.9 neurons but very few astrocytes in 3-week tracing. Furthermore, these activated NSCs were maintained for ...
Source: Fight Aging! - January 2, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2021: Progress Towards the Treatment of Aging as a Medical Condition
Well, here we are again, at the end of another pandemic year, a year older and - hopefully - a year wiser and more knowledgeable. I said all that really needs to be said on the topic of COVID-19 as an age-related condition at the end of last year. We might hope that, given widespread vaccination, the pandemic will become a topic of diminishing importance as the year ahead progresses, even given the present round of variants, fears, and reintroduction of restrictions. Advocacy for Aging Research Have we finally made significant progress in convincing the world that aging is the cause of age-related disease, th...
Source: Fight Aging! - December 31, 2021 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

Fight Aging! Newsletter, December 20th 2021
In conclusion, the low dose, prolonged angiotensin II exposure is associated with the induction of senescence in kidneys and the promotion of an inflammatory microenvironment through both secreted factors and immune cells. Endothelial cells appear to be a major cell type impacted. The elimination of senescent cells in the INK-ATTAC transgenic model prevents these effects of angiotensin II and reveals a novel pathophysiologic mechanism amenable to targeting by senolytic drugs in development. CYTOR Upregulation as a Path to Improved Muscle Function in Later Life https://www.fightaging.org/archives/2021/12/cytor-...
Source: Fight Aging! - December 19, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Catheter-Deliverable Biomaterial Sealants: Interview with Natalie Artzi, Co-founder of BioDevek
BioDevek, a medtech company based in Cambridge, Massachusetts, has developed a biomaterial adhesive that acts to seal internal wounds and incisions. The material is designed to be sprayed through a catheter, and the primary application for the technology so far is to act as a sealant following colonic polyp resection. At present, following polyp resection, surgeons can use polyp clips to seal the resection site, which can hamper wound healing, or use no sealant at all, leading to an open wound that comes with a risk of bleeding or other complications. This can lead to additional surgeries to correct the issue and is inc...
Source: Medgadget - November 30, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive GI Materials Plastic Surgery BioDevek Source Type: blogs