Fight Aging! Newsletter, February 19th 2024
This study aimed to explore the metabolic mechanisms and potential biomarkers associated with declining HGS among older adults. We recruited 15 age- and environment-matched inpatients (age, 77-90 years) with low or normal HGS. Liquid chromatography-mass spectrometry (LC-MS) and 16S ribosomal DNA (rDNA) gene sequencing were performed to analyze the metabolome of serum and stool samples and the gut microbiome composition of stool samples. Spearman's correlation analysis was used to identify the potential serum and fecal metabolites associated with HGS. We assessed the levels of serum and fecal metabolites belonging to...
Source: Fight Aging! - February 18, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 15th 2024
In conclusion, FMD cycles have high potential to be effective in increasing the toxicity of a range of therapies against ALL and other blood cancers and should be tested in randomized clinical trials, especially in combination with immunotherapy and low toxicity cancer therapies. In summary, we present a new strategy for improving leukemia treatment by combining FMD with chemotherapy to promote the killing of ALL cells in part by an immune-dependent mechanism. Fasting/FMD has been shown to reduce chemotherapy-associated toxicity in pre-clinical and clinical studies and thus represents a safe and potentially effectiv...
Source: Fight Aging! - January 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, December 18th 2023
In conclusion, given the relative safety and the favourable effects of aspirin, its use in cancer seems justified, and ethical implications of this imply that cancer patients should be informed of the present evidence and encouraged to raise the topic with their healthcare team. « Back to Top Aged Transplant Organs Cause Harm to Younger Recipients https://www.fightaging.org/archives/2023/12/aged-transplant-organs-cause-harm-to-younger-recipients/ Old tissues are dysfunctional in ways that young tissues are not. This has always been known in the context of organ transplants, but absent me...
Source: Fight Aging! - December 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Occlusion myocardial infarction is a clinical diagnosis
Written by Willy Frick (@Willyhfrick).  Willy is a cardiology fellow with a keen interest in the ECG in OMI.A woman in her late 70s presented with left arm pain. The arm pain started the day prior when she was at the dentist ' s office for a root canal. Her systolic blood pressure at the dentist was over 200 mm Hg. She was given nitroglycerin which improved her blood pressure, and she completed the procedure. Her arm pain abated. The pain returned that evening and woke her from sleep. She eventually fell back asleep, and woke up feeling normal the next day (the day of presentation). After dinner the day of presentatio...
Source: Dr. Smith's ECG Blog - December 11, 2023 Category: Cardiology Authors: Willy Frick Source Type: blogs

AI ’ s Unforeseen Medical Discoveries: The Curious Case Of Unusual Associations
Artificial intelligence can do a plethora of astonishing things, which has been discussed thoroughly in the past year. We train models to assist medical work, from administration to image analysis, from triage to mental health support. And every now and then AI has curious medical discoveries, detecting things that – to the best of our human knowledge – should not be detectable from the input data. Like knowing the race of the patient from chest X-rays alone. These unusual associations present brand-new challenges to medical professionals. In these cases, the medical detective work has a new aim: to understa...
Source: The Medical Futurist - November 28, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF Artificial Intelligence in Medicine digital health Healthcare technology AI Source Type: blogs

Kento Health Raises $4.1 Million CAD to Bring AI to Cardiovascular Care
Dialogue Alumni’s New Startup is Gearing up to Strike Hard in the Battle Against the Leading Cause of Death Montréal-based healthtech startup Kento Health has closed a $4.1 million CAD ($3 million USD) pre-seed financing round. The round was led by Boreal Ventures and N49P and saw participation from Broom Ventures, Graphite Ventures, and several other strategic angel investors as well as an undisclosed US-based medical institution. Kento claims it is poised to make a substantial impact in the fight against the world’s leading cause of death by using technology like artificial intelligence (AI). “This funding not...
Source: EMR and HIPAA - November 8, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alex Norman Boreal Ventures Broom Ventures David Charbonneau Dialogue Health Graphite Ventures Health IT Funding Health IT Fundings Health IT Investment Jonah Davies Kento Kento Health Max Leca Source Type: blogs

3D Printing In Medicine And Healthcare – The Ultimate List
3D printing has demonstrated huge potential for the future of medicine in the previous years, and its development is unstoppable. See the impressive list of 3D-printed healthcare materials and medical equipment below! How does 3D printing in medicine work? 3D printing in medicine is part of the innovative process called additive manufacturing, which means producing three-dimensional solid objects from a digital file. How the technology works, we explained in our article on bioprinting here. As technology evolves, researchers work on various solutions. For example, engineers from the University of Buffalo have ...
Source: The Medical Futurist - November 7, 2023 Category: Information Technology Authors: berci.mesko Tags: 3D Printing Biotechnology Future of Medicine Healthcare Design Medical Education Personalized Medicine 3d printed biomaterial tissue engineering Video bioprinting GC1 Innovation Source Type: blogs

Fight Aging! Newsletter, October 30th 2023
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection. « Back to Top (Source: Fight Aging!)
Source: Fight Aging! - October 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

“ Proportionate ” vs “ Disproportionate ” Mitral regurgitation : A new concept in the making
Cardiologists have always struggled to classify, assess, and grade one important valve disease, which is Mitral regurgitation. While valve replacement is the ultimate treatment, the timing of MVR is still a big debate. Apart from valve replacement, valve repair is a strong contender in selected patients. In recent times, cardiologists have made great strides to grab MR patients from cardaic surgeons. MitraClip, a percutaneous edge stitching , is possible with a varying degree of success. Mitral valve edge-to-edge repair (MEER) is an interventional clone of Alfieri surgery that has shown conflicting results in the MITRA-...
Source: Dr.S.Venkatesan MD - October 25, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized acc aha esc alfiery repair annals of thoracic surgery carillon device functional MR meer millipede itis device mitra clip mitra fr cs coapt mitral annulus mitral regurtitation mitral valve replacement mitral vlave e Source Type: blogs

What is the normal Pericardial thickness ?
An unusal conversation with a flamboyant student fellow, May I know , What is the normal Pericardial thickness, ? Which pericardium you mean sir ? ,Parietal or visceral? Would like to know both . It is variable sheet of tissue .You want the thinnest part or thickest part ? Don’t beat around the bush .Tell some answer. You want, autopsy thickness, or real life thickness as surgeon sees it ? I want it in practical Imaging modality Do you want Echo, CT or MRI thickness ? I should say , its too much for a first-year fellow in reverse questioning! Ok relax sir, shall I tell the systolic ...
Source: Dr.S.Venkatesan MD - October 20, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Weekly Roundup – August 19, 2023
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week. Helping Children With Gamified Interactive Physiotherapy. Psychiatrist Dr. Geoff Frost struggled to encourage pediatric patients with spinal muscular atrophy to do their necessary exercises. As he explained to Colin Hung, that’s why Raft Digital Therapeutics created a game called Cloud Bazaar to captures a child’s movement as a way to advance...
Source: EMR and HIPAA - August 19, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs

Bonus Features – August 13, 2023 – 75% of executives thing generative AI has reached the point where it will reshape healthcare, 64% of patients would trust AI over a doctor to make a diagnosis, and more,
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News The Drug Enforcement Administration will hold listening sessions Sept. 12 and 13 to discuss allowing a “special registration” to allow physicians to remotely prescribe certain controlled substances without the ...
Source: EMR and HIPAA - August 13, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT American Telemedicine Association Ana Sirbu AssureCare ATA ATA Nexus Azure Bain CitiusTech DEA DrFirst eClinicalWorks eCW Epic Generative AI Healthcare Generative AI Healthcare IT Today Bonus Features health Source Type: blogs

Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity. « Back to Top (Source: Fight Aging!)
Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Outpatient Vascular Care: Good, bad or ugly?
BY ANISH KOKA Filling in the holes of recent stories in the New York Times, and Propublica on the outpatient care of patients with peripheral arterial disease Most have gotten used to egregiously bad coverage of current events that fills the pages of today’s New York Times, but even by their now very low standards a recent telling of a story about peripheral artery disease was very bad. The scintillating allegation by Katie Thomas, Jessica Silver-Greenberg and Robert Gebeloff is that “medical device makers are bankrolling doctors to perform artery clearing procedures that can lead to amputations...
Source: The Health Care Blog - July 24, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Anish Koka Medical Devices Outpatient vascular care Source Type: blogs