Fight Aging! Newsletter, February 28th 2022

In conclusion, as BMI and waist circumference are related to elevations of immune markers in the IL-6 pathway, chronic inflammation might be an important mediator of the relationship between BMI and frailty. Fat Tissue Becomes Dysfunctional with Age as Mitochondria Falter https://www.fightaging.org/archives/2022/02/fat-tissue-becomes-dysfunctional-with-age-as-mitochondria-falter/ Mitochondria are effectively power plants, hundreds of them working in every cell to produce chemical energy store molecules to power cellular processes. Mitochondrial function declines with age, unfortunately, for underlying reasons that appear to involve gene expression changes that reduce the effectiveness of mitochondrial quality control mechanisms. This has profound effects on tissue function throughout the body, and is an important contribution to degenerative aging. Here, researchers discuss some of the effects on fat tissue specifically. Researchers looked at the role of age and physical training in maintaining fat tissue function. Specifically, they studied mitochondria, the tiny power plants within fat cells. Mitochondria convert calories from food to supply cells with energy. To maintain the life processes within cells, they need to function optimally. The researchers compared mitochondrial performance across a range of young and older untrained, moderately trained and highly exercise trained men. The results demonstrate that the ability of mitochondria to resp...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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