Four-Step
Synthesis of the Antimalarial Cardamom Peroxide
via an Oxygen Stitching Strategy
Journal of the American Chemical SocietyDOI: 10.1021/ja502208z (Source: Journal of the American Chemical Society)
Source: Journal of the American Chemical Society - March 27, 2014 Category: Chemistry Authors: Xirui Hu and Thomas J. Maimone Source Type: research
Simultaneous HPLC determination of 22 components of essential oils; method robustness with experimental design
A Porel, Y Sanyal, A KunduIndian Journal of Pharmaceutical Sciences 2014 76(1):19-30The aim of the present study was the development and validation of a simple, precise and specific reversed phase HPLC method for the simultaneous determination of 22 components present in different essential oils namely cinnamon bark oil, caraway oil and cardamom fruit oil. The chromatographic separation of all the components was achieved on Wakosil-II C 18 column with mixture of 30 mM ammonium acetate buffer (pH 4.7), methanol and acetonitrile in different ratio as mobile phase in a ternary linear gradient mode. The calibration graphs plot...
Source: Indian Journal of Pharmaceutical Sciences - March 11, 2014 Category: Drugs & Pharmacology Authors: A PorelY SanyalA Kundu Source Type: research
Asymmetric patterns of Reassortment and Concerted Evolution in Cardamom bushy dwarf virus.
Abstract
Nanoviruses are single-stranded DNA (ssDNA) plant viruses which have multipartite genomes consisting of discrete, individually encapsidated components. This multipartite strategy may lead to high rates of reassortment, whereby entire genome components are exchanged among different strains. However, few studies have explored the extent to which reassortment shapes the genetic diversity of nanovirus populations. Here we present an extensive analysis of reassortment among 163 Cardamom bushy dwarf virus (CBDV; Nanoviridae family, Babuvirus genus) isolates collected in Northeast India. We also examined...
Source: Infection, Genetics and Evolution - March 5, 2014 Category: Genetics & Stem Cells Authors: Savory FR, Ramakrishnan U Tags: Infect Genet Evol Source Type: research
Enantiomeric Separation in Comprehensive Twoâdimensional Gas Chromatography with Accurate Mass Analysis.
Abstract
Chiral comprehensive twoâdimensional gas chromatography (eGCÃGC) coupled to quadrupoleâaccurate mass timeâofâflight mass spectrometry (QTOFMS) was evaluated for its capability to report the chiral composition of several monoterpenes, namely, αâpinene, βâpinene, and limonene in cardamom oil. Enantiomers in a standard mixture were fully resolved by direct enantiomericâGC analysis with a 2,3âdiâOâmethylâ6âtâbutylsilyl derivatized βâcyclodextrin phase; however, the (+)â(R)âlimonene enantiomer in cardamom oil wa...
Source: Chirality - January 13, 2014 Category: Molecular Biology Authors: Chin ST, Nolvachai Y, Marriott PJ Tags: Chirality Source Type: research
Isolation and identification of new phytoconstituents from the fruit extract of Amomum subulatum Roxb.
Abstract
The fruits of Amomum subulatum Roxb. (Zingiberaceae) (large cardamom), cultivated in the northern Himalayas, are used to treat stomach disorders, pulmonary diseases and liver complaints. Phytochemical investigation of the fruits led to the isolation of four new chemical compounds characterised as geranil-3(10)-en-9-olyl octadec-9-enoate, geranil-3(10)-en-9-carboxyl-β-d-arabinopyranoside, geranilan-9-carboxy-α-l-arabinopyranoside and stigmast-5-en-3β-ol-3β-d-arabinopyranosyl-2'-(3″-methoxy) benzoate-3'-octadec-9‴,12‴,15‴-trienoate, along with the known compounds oleodilinolein and glyce...
Source: Natural Product Research - November 26, 2013 Category: Biochemistry Authors: Kumar G, Chauhan B, Ali M Tags: Nat Prod Res Source Type: research
Antimicrobial activity of the bioactive components of essential oils from Pakistani spices against Salmonella and other multi-drug resistant bacteria
Background:
The main objective of this study was the phytochemical characterization of four indigenous essential oils obtained from spices and their antibacterial activities against the multidrug resistant clinical and soil isolates prevalent in Pakistan, and ATCC reference strains.
Methods:
Chemical composition of essential oils from four Pakistani spices cumin (Cuminum cyminum), cinnamon (Cinnamomum verum), cardamom (Amomum subulatum) and clove (Syzygium aromaticum) were analyzed on GC/MS. Their antibacterial activities were investigated by minimum inhibitory concentration (MIC) and Thin-Layer Chromatography-Bioautograph...
Source: BMC Complementary and Alternative Medicine - October 14, 2013 Category: Complementary Medicine Authors: Rasheeha NaveedIftikhar HussainAbdul TawabMuhammad TariqMoazur RahmanSohail HameedM MahmoodAbu SiddiqueMazhar Iqbal Source Type: research
Nine novel DNA components associated with the foorkey disease of large cardamom: Evidence of a distinct babuvirus species in Nanoviridae.
This study shows further diversity in the genus Babuvirus.
PMID: 24091364 [PubMed - as supplied by publisher] (Source: Virus Research)
Source: Virus Research - September 30, 2013 Category: Virology Authors: Mandal B, Shilpi S, Barman AR, Mandal S, Varma A Tags: Virus Res Source Type: research
A Study on Antioxidant Potency and Antibacterial Activity of Water Extracts of Some Spices Widely Consumed in Iranian Diet
This study showed that the water extracts of sumac, laurel and barberry had the strongest antioxidant activity while the sumac and barberry extracts exhibited the highest antibacterial activity against four foodborne pathogenic bacteria. Therefore, the water extracts of sumac, laurel and barberry can be used as effective preservatives in food systems. (Source: Journal of Food Biochemistry)
Source: Journal of Food Biochemistry - July 14, 2013 Category: Food Science Authors: Javad Aliakbarlu, Shadieh Mohammadi, Surur Khalili Tags: Full Article Source Type: research
Expression and immunological characterization of cardamom mosaic virus coat protein displaying HIV gp41 epitopes
Abstract
The coat protein of cardamom mosaic virus (CdMV), a member of the genus Macluravirus, assembles into virus‐like particles when expressed in an Escherichia coli expression system. The N and C‐termini of the coat protein were engineered with the Kennedy peptide and the 2F5 and 4E10 epitopes of gp41 of HIV. The chimeric proteins reacted with sera from HIV positive persons and also stimulated secretion of cytokines by peripheral blood mononuclear cells from these persons. Thus, a system based on the coat protein of CdMV can be used to display HIV‐1 antigens. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - May 14, 2013 Category: Microbiology Authors: Subha Damodharan, Ravindra Gujar, Sathyamurthy Pattabiraman, Manohar Nesakumar, Luke Elizabeth Hanna, Ramanathan D Vadakkuppattu, Ramakrishnan Usha Tags: Original Article Source Type: research
Expression and immunological characterization of Cardamom mosaic virus coat protein displaying HIV gp41 epitopes
Abstract
The coat protein of Cardamom mosaic virus, a member of genus Macluravirus, assembles into virus‐like particles when expressed in an E.coli expression system. The N and C‐termini of the coat protein were engineered with the Kennedy peptide and the 2F5 and 4E10 epitopes of gp41 of HIV. The chimeric proteins reacted with sera from HIV positive persons and also stimulated the secretion of cytokines in peripheral blood mononuclear cells from them. Thus the system based on the coat protein of Cardamom mosaic virus can be used to display HIV‐1 antigens. (Source: Microbiology and Immunology)
Source: Microbiology and Immunology - March 19, 2013 Category: Microbiology Authors: Subha Damodharan, Ravindra Gujar, Sathyamurthy Pattabiraman, Manohar Nesakumar, Luke Elizabeth Hanna, Ramanathan D Vadakkuppattu, Ramakrishnan Usha Tags: Original Article Source Type: research
