Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity
Curr Opin Pharmacol. 2022 Mar 1;63:102187. doi: 10.1016/j.coph.2022.102187. Online ahead of print.ABSTRACTCardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the history and culture of human nutrition, spices have been emphasized for their wide range of economic and medical applications in addition to being used as a food-flavoring agent and food preservative. Currently, an increasing number of studies have focused on the health benefits of spices in preventing cardiovascular diseases, particularly their antioxidant effects against card...
Source: Current Opinion in Pharmacology - March 4, 2022 Category: Drugs & Pharmacology Authors: Jia Liu Qing Zhang Ting Tao Ling-Yu Wang Jia-Yi Sun Chun-Jie Wu Wen-Jun Zou Source Type: research
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity
Curr Opin Pharmacol. 2022 Mar 1;63:102187. doi: 10.1016/j.coph.2022.102187. Online ahead of print.ABSTRACTCardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the history and culture of human nutrition, spices have been emphasized for their wide range of economic and medical applications in addition to being used as a food-flavoring agent and food preservative. Currently, an increasing number of studies have focused on the health benefits of spices in preventing cardiovascular diseases, particularly their antioxidant effects against card...
Source: Current Opinion in Pharmacology - March 4, 2022 Category: Drugs & Pharmacology Authors: Jia Liu Qing Zhang Ting Tao Ling-Yu Wang Jia-Yi Sun Chun-Jie Wu Wen-Jun Zou Source Type: research
Cardamom: Potential Health Benefits
The spice cardamom, also known historically as the “queen of spices,” is produced from the seeds of the plant Elettaria cardamomum, which is cultivated commercially on plantations in the south of India, Sri Lanka, Central America, and Southeast Asia. It enhances both sweet and savory dishes in many regions around the world. In ancient traditional medicines, cardamom was used to alleviate digestive disorders and obesity, and even today, it is used in local cultures for individuals with ailments such as bronchitis, depression, dysentery, influenza, and infections. This narrative review discusses human investigations of c...
Source: Nutrition Today - January 1, 2022 Category: Nutrition Tags: Food Science Source Type: research
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
In Silico Biol. 2021 Dec 2. doi: 10.3233/ISB-210226. Online ahead of print.ABSTRACTDifferentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process as a consequence of the limited number of cell types. Moreover, mRNA is known to be generally produced by bursts, which can give rise to highly variable non-Gaussian behavior, making the estimation of a GRN from transcriptional profiles challengin...
Source: In Silico Biol - December 13, 2021 Category: Biology Authors: Elias Ventre Source Type: research
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
In Silico Biol. 2021 Dec 2. doi: 10.3233/ISB-210226. Online ahead of print.ABSTRACTDifferentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process as a consequence of the limited number of cell types. Moreover, mRNA is known to be generally produced by bursts, which can give rise to highly variable non-Gaussian behavior, making the estimation of a GRN from transcriptional profiles challengin...
Source: In Silico Biol - December 13, 2021 Category: Biology Authors: Elias Ventre Source Type: research
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
In Silico Biol. 2021 Dec 2. doi: 10.3233/ISB-210226. Online ahead of print.ABSTRACTDifferentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process as a consequence of the limited number of cell types. Moreover, mRNA is known to be generally produced by bursts, which can give rise to highly variable non-Gaussian behavior, making the estimation of a GRN from transcriptional profiles challengin...
Source: In Silico Biol - December 13, 2021 Category: Biology Authors: Elias Ventre Source Type: research
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
In Silico Biol. 2021 Dec 2. doi: 10.3233/ISB-210226. Online ahead of print.ABSTRACTDifferentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process as a consequence of the limited number of cell types. Moreover, mRNA is known to be generally produced by bursts, which can give rise to highly variable non-Gaussian behavior, making the estimation of a GRN from transcriptional profiles challengin...
Source: In Silico Biol - December 13, 2021 Category: Biology Authors: Elias Ventre Source Type: research
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
In Silico Biol. 2021 Dec 2. doi: 10.3233/ISB-210226. Online ahead of print.ABSTRACTDifferentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process as a consequence of the limited number of cell types. Moreover, mRNA is known to be generally produced by bursts, which can give rise to highly variable non-Gaussian behavior, making the estimation of a GRN from transcriptional profiles challengin...
Source: In Silico Biol - December 13, 2021 Category: Biology Authors: Elias Ventre Source Type: research
Reverse engineering of a mechanistic model of gene expression using metastability and temporal dynamics
In Silico Biol. 2021 Dec 2. doi: 10.3233/ISB-210226. Online ahead of print.ABSTRACTDifferentiation can be modeled at the single cell level as a stochastic process resulting from the dynamical functioning of an underlying Gene Regulatory Network (GRN), driving stem or progenitor cells to one or many differentiated cell types. Metastability seems inherent to differentiation process as a consequence of the limited number of cell types. Moreover, mRNA is known to be generally produced by bursts, which can give rise to highly variable non-Gaussian behavior, making the estimation of a GRN from transcriptional profiles challengin...
Source: In Silico Biol - December 13, 2021 Category: Biology Authors: Elias Ventre Source Type: research
Essential Oils from Spices Inhibit Cholinesterase Activity and Improve Behavioral Disorder in AlCl3 Induced Dementia
Chem Biodivers. 2021 Dec 2. doi: 10.1002/cbdv.202100443. Online ahead of print.ABSTRACTThe chemical compositions of essential oils (EOs) prepared from six spices including cinnamon, amomum tsao-ko, cardamom, amomum, black pepper and white pepper were analyzed by gas chromatography-mass spectrometry (GC-MS), which led to identify almost 200 volatile compounds. All EOs of spices showed cholinesterase inhibitory activity. Among them, pepper EO showed most potent acetylcholinesterase (AChE) inhibitory activity with IC 50 values of 8.54 μg/mL (black pepper EO) and 5.02 µg/mL (white pepper EO). Molecular docking and in vitro v...
Source: Chemistry and Biodiversity - December 2, 2021 Category: Biochemistry Authors: Shu-Xia Chen Jia-Yao Xiang Jia-Xin Han Yang Feng Hai-Zhou Li Hao Chen Min Xu Source Type: research
Essential Oils from Spices Inhibit Cholinesterase Activity and Improve Behavioral Disorder in AlCl3 Induced Dementia
Chem Biodivers. 2021 Dec 2. doi: 10.1002/cbdv.202100443. Online ahead of print.ABSTRACTThe chemical compositions of essential oils (EOs) prepared from six spices including cinnamon, amomum tsao-ko, cardamom, amomum, black pepper and white pepper were analyzed by gas chromatography-mass spectrometry (GC-MS), which led to identify almost 200 volatile compounds. All EOs of spices showed cholinesterase inhibitory activity. Among them, pepper EO showed most potent acetylcholinesterase (AChE) inhibitory activity with IC 50 values of 8.54 μg/mL (black pepper EO) and 5.02 µg/mL (white pepper EO). Molecular docking and in vitro v...
Source: Chemistry and Biodiversity - December 2, 2021 Category: Biochemistry Authors: Shu-Xia Chen Jia-Yao Xiang Jia-Xin Han Yang Feng Hai-Zhou Li Hao Chen Min Xu Source Type: research
A study of vegetable oil modified QCM sensor to detect β-pinene in Indian cardamom
Talanta. 2022 Jan 1;236:122837. doi: 10.1016/j.talanta.2021.122837. Epub 2021 Sep 2.ABSTRACTA quartz crystal microbalance (QCM) sensor was developed in this study with the vegetable oil from olive (OLV-QCM) to detect an important volatile organic compound, β-pinene in Indian cardamom. Hydrophobic vegetable oil from olive, which contains oleic acid and omega-9, a monounsaturated fatty acid was found to be suitable for binding β-pinene through non-covalent bonds. The fabricated QCM sensor coating was examined with the field emission scanning electron microscope (FESEM) and Fourier-transform infrared spectroscopy (FTIR) to ...
Source: Talanta - October 12, 2021 Category: Chemistry Authors: Nilava Debabhuti Sumani Mukherjee Swarnali Neogi Prolay Sharma Ugir Hossain Sk Soumen Maiti Mousumi Poddar Sarkar Bipan Tudu Nabarun Bhattacharyya Rajib Bandyopadhyay Source Type: research
A study of vegetable oil modified QCM sensor to detect β-pinene in Indian cardamom
Talanta. 2022 Jan 1;236:122837. doi: 10.1016/j.talanta.2021.122837. Epub 2021 Sep 2.ABSTRACTA quartz crystal microbalance (QCM) sensor was developed in this study with the vegetable oil from olive (OLV-QCM) to detect an important volatile organic compound, β-pinene in Indian cardamom. Hydrophobic vegetable oil from olive, which contains oleic acid and omega-9, a monounsaturated fatty acid was found to be suitable for binding β-pinene through non-covalent bonds. The fabricated QCM sensor coating was examined with the field emission scanning electron microscope (FESEM) and Fourier-transform infrared spectroscopy (FTIR) to ...
Source: Talanta - October 12, 2021 Category: Chemistry Authors: Nilava Debabhuti Sumani Mukherjee Swarnali Neogi Prolay Sharma Ugir Hossain Sk Soumen Maiti Mousumi Poddar Sarkar Bipan Tudu Nabarun Bhattacharyya Rajib Bandyopadhyay Source Type: research
A study of vegetable oil modified QCM sensor to detect β-pinene in Indian cardamom
Talanta. 2022 Jan 1;236:122837. doi: 10.1016/j.talanta.2021.122837. Epub 2021 Sep 2.ABSTRACTA quartz crystal microbalance (QCM) sensor was developed in this study with the vegetable oil from olive (OLV-QCM) to detect an important volatile organic compound, β-pinene in Indian cardamom. Hydrophobic vegetable oil from olive, which contains oleic acid and omega-9, a monounsaturated fatty acid was found to be suitable for binding β-pinene through non-covalent bonds. The fabricated QCM sensor coating was examined with the field emission scanning electron microscope (FESEM) and Fourier-transform infrared spectroscopy (FTIR) to ...
Source: Talanta - October 12, 2021 Category: Chemistry Authors: Nilava Debabhuti Sumani Mukherjee Swarnali Neogi Prolay Sharma Ugir Hossain Sk Soumen Maiti Mousumi Poddar Sarkar Bipan Tudu Nabarun Bhattacharyya Rajib Bandyopadhyay Source Type: research
A study of vegetable oil modified QCM sensor to detect β-pinene in Indian cardamom
Talanta. 2022 Jan 1;236:122837. doi: 10.1016/j.talanta.2021.122837. Epub 2021 Sep 2.ABSTRACTA quartz crystal microbalance (QCM) sensor was developed in this study with the vegetable oil from olive (OLV-QCM) to detect an important volatile organic compound, β-pinene in Indian cardamom. Hydrophobic vegetable oil from olive, which contains oleic acid and omega-9, a monounsaturated fatty acid was found to be suitable for binding β-pinene through non-covalent bonds. The fabricated QCM sensor coating was examined with the field emission scanning electron microscope (FESEM) and Fourier-transform infrared spectroscopy (FTIR) to ...
Source: Talanta - October 12, 2021 Category: Chemistry Authors: Nilava Debabhuti Sumani Mukherjee Swarnali Neogi Prolay Sharma Ugir Hossain Sk Soumen Maiti Mousumi Poddar Sarkar Bipan Tudu Nabarun Bhattacharyya Rajib Bandyopadhyay Source Type: research
