Environmental, Occupational, and Demographic Risk Factors for Clinical Scrub Typhus, Bhutan
This study has informed public health policies and awareness programs for healthcare workers through development of National Guidelines for Prevention, Treatment and Control of Scrub Typhus in Bhutan.PMID:37081000 | DOI:10.3201/eid2905.221430 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 23, 2023 Category: Infectious Diseases Authors: Tandin Zangpo Yoenten Phuentshok Kezang Dorji Chencho Dorjee Sithar Dorjee Peter Jolly Roger Morris Nelly Marquetoux Joanna McKenzie Source Type: research

Environmental, Occupational, and Demographic Risk Factors for Clinical Scrub Typhus, Bhutan
This study has informed public health policies and awareness programs for healthcare workers through development of National Guidelines for Prevention, Treatment and Control of Scrub Typhus in Bhutan.PMID:37081000 | DOI:10.3201/eid2905.221430 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - April 22, 2023 Category: Infectious Diseases Authors: Tandin Zangpo Yoenten Phuentshok Kezang Dorji Chencho Dorjee Sithar Dorjee Peter Jolly Roger Morris Nelly Marquetoux Joanna McKenzie Source Type: research

One model fits all: Combining inference and simulation of gene regulatory networks
by Elias Ventre, Ulysse Herbach, Thibault Espinasse, G érard Benoit, Olivier Gandrillon The rise of single-cell data highlights the need for a nondeterministic view of gene expression, while offering new opportunities regarding gene regulatory network inference. We recently introduced two strategies that specifically exploit time-course data, where single-cell profiling is performed after a stimulus: HARISSA, a mechanistic network model with a highly efficient simulation procedure, and CARDAMOM, a scalable inference method seen as model calibration. Here, we combine the two approaches and show that the same model driven ...
Source: PLoS Computational Biology - March 27, 2023 Category: Biology Authors: Elias Ventre Source Type: research

Correction: Effect of green cardamom on the expression of genes implicated in obesity and diabetes among obese women with polycystic ovary syndrome: a double blind randomized controlled trial
(Source: Genes and Nutrition)
Source: Genes and Nutrition - January 27, 2023 Category: Nutrition Source Type: research

Molecules, Vol. 28, Pages 1093: Antioxidant Activity and GC-MS Profile of Cardamom (Elettaria cardamomum) Essential Oil Obtained by a Combined Extraction Method & mdash;Instant Controlled Pressure Drop Technology Coupled with Sonication
This study analyzed 13 different treatments with varying saturated steam processing temperatures (SSPT), thermal processing times (TPT), and 1 control. The results showed that CEO yield increased significantly by DIC (140 °C and 30 s) and UAE compared to the control (22.53% vs. 15.6%). DIC 2 (165 °C, 30 s) showed the highest DPPH inhibition (79.48%) and the best Trolox equivalent antioxidant capacity (TEAC) by the control with 0.60 uMTE/g. The GC/MS analysis showed 28 volatile constituents, withα-Terpinyl acetate, geranyl oleate, and oleic acid being the most abundant. DIC (140 &am...
Source: Molecules - January 21, 2023 Category: Chemistry Authors: Nora E. Torres Castillo Giselle D. Teresa-Mart ínez Maritza Alonzo-Mac ías Carmen T éllez-Pérez Jos é Rodríguez-Rodríguez Juan Eduardo Sosa-Hern ández Roberto Parra-Sald ívar Elda M. Melchor-Mart ínez Anaberta Cardador-Mart ínez Tags: Article Source Type: research

Effect of green cardamom on the expression of genes implicated in obesity and diabetes among obese women with polycystic ovary syndrome: a double blind randomized controlled trial
ConclusionThis current study showed that the administration of green cardamom is a beneficial approach for improving anthropometric, glycemic, and androgen hormones, as well as obesity and diabetes genes expression in PCOS women under the low-calorie diet.Trial registrationThis trial was registered with the Iranian Clinical Trials Registry (registration number: IRCT20200608047697N1). 1 August, 2020;https://www.irct.ir/trial/48748 (Source: Genes and Nutrition)
Source: Genes and Nutrition - December 15, 2022 Category: Nutrition Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research

Cardamom Extract Alleviates the Oxidative Stress, Inflammation and Apoptosis Induced during Acetaminophen-Induced Hepatic Toxicity via Modulating Nrf2/HO-1/NQO-1 Pathway
CONCLUSION: CARD extract mitigated the hepatic toxicity induced by APAP. The underlying mechanism of action of such hepato-protective action may be through upregulation of the Nrf2/HO-1/NQO-1 pathway with subsequent alleviation of the oxidative stress, inflammation and apoptosis induced by APAP. Many of the compounds identified in the CARD extract could be attributed to this pharmacological action of the extract.PMID:36354677 | DOI:10.3390/cimb44110365 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Essraa A R Alkhalifah Amjad A Alobaid Marwah A Almajed Manar K Alomair Lama S Alabduladheem Sarah F Al-Subaie Abdullah Akbar Mahesh V Attimarad Nancy S Younis Maged E Mohamed Source Type: research