Health Data Analytics Institute (HDAI) Announces $31 Million Funding Round to Scale Predictive Risk Platform
Investment will Drive Expansion of New AI Platform, In Use by Houston Methodist and Additional Health Systems Health Data Analytics Institute (HDAI)— an artificial intelligence (AI) company focused on empowering clinicians, optimizing care pathways, and improving patient outcomes — today announced an oversubscribed Series C financing to scale its predictive risk platform. “We are grateful for the continued support of our investors, who recognize the value to be unlocked by transforming huge volumes of health data into actionable insights,” said Nassib Chamoun, Founder and CEO at HDAI. “HDAI is commi...
Source: EMR and HIPAA - October 17, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Cleveland Clinic Dana-Farber Cancer Institute Ed Kania HDAI Health Data Analytics Institute Health IT Funding Health IT Fundings Health IT Investment HealthVision Hlth Houston Methodist Nassib Cham Source Type: blogs

Midi Health Raises $25M in Series A Funding Led by GV (Google Ventures) to Expand Access to Expert and Affordable Midlife Care for Women
The Leading Virtual Clinic Delivering Insurance-Covered, Expert Care for Women Perimenopause and Menopause, Midi Health Plans Major Expansion of National Footprint Midi Health, the emerging digital leader in women’s midlife healthcare, today announced the close of a $25M Series A funding round led by GV (Google Ventures). Investors Frederique Dame and Cathy Friedman from GV are joined by current investors Felicis, Semper Virens, Icon, 25M, and Operator Collective, bringing the company’s total funding raised to date to $40M. In the year since the company officially launched to consumers, Midi Health has...
Source: EMR and HIPAA - October 16, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT 25M Cathy Friedman Felicis Frederique Dame Google Ventures GV Health IT Funding Health IT Fundings Health IT Investment ICON Joanna Strober Midi Health Operator Collective Semper Virens Source Type: blogs

Fight Aging! Newsletter, October 16th 2023
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution. « Back to Top Delivering Senolytic Nanoparticles to Atheroscle...
Source: Fight Aging! - October 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards More Selective Ways to Block Unwanted Inflammation
Control of chronic inflammation may turn out to be one of the more important themes in the treatment of aging as a medical condition. Senescent cells generate inflammatory signaling, but removing that contribution is likely the easiest aspect of the problem. Many forms of age-related cellular damage and dysfunction generate constant, unwanted, excess inflammation through interactions and signals that are used during a normal, desirable inflammatory reaction, such as to injury or infection. Thus interfering in these mechanisms must be very selective; simply blockading a given signal has undesirable side-effects, such as a w...
Source: Fight Aging! - October 13, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Popular Weight Loss Drug That Also Fight Cancer
A popular drug that treats obesity may also help to destroy cancer cells. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - October 12, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Cancer Source Type: blogs

Adoptive Transfer of Regulatory T Cells as a Way to Treat Atherosclerosis
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution. (Source: Fight Aging!)
Source: Fight Aging! - October 11, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Age-Related DNA Damage and Epigenetic Changes
This review paper covers both genetic and epigenetic changes that occur with age, taking a broad look at everything from telomere length to stochastic mutational damage to alterations in chromatin structure. As for all aspects of aging at the level of cellular biochemistry, it is easier to catalog than it is to determine relationships between these items, or to determine whether one characteristic of aging cellular biochemistry is more or less important than another when it comes to age-related disease and loss of function. Greater funding for the field would allow researchers to take the best of brute force approaches, wh...
Source: Fight Aging! - October 11, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Ozempic: 3 Amazing Benefits Of The Weight Loss Drug
Reducing weight and potentially helping to fight cancer. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - October 10, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Weight Loss Source Type: blogs

To Drive Value, EHRs Need to Actually be Usable
The following is a guest article by Khalid Al-Maskari, Founder and CEO of Health Information Management Systems (HiMS) EHRs are ubiquitous because they’re useful – but how useful are they really, and to whom? The truth is that an EHR by definition serves multiple masters, satisfying some more than others. For many clinicians, EHRs have actually been a disservice, a major factor in burnout. That’s because they weren’t invented to help clinicians in the first place. “Many EHR products were designed with billing, payer requirements, and meaningful use criteria in mind rather than clinician use, resulting in a user e...
Source: EMR and HIPAA - October 10, 2023 Category: Information Technology Authors: Guest Author Tags: Ambulatory EMR-EHR Health IT Company Healthcare IT EHR UI EHR Usability Health Information Management Systems Hims Khalid Al-Maskari Patient Care Patient-Provider Relationship Value Based Care Source Type: blogs

Digging Deeper into the Senescence-Associated Secretory Phenotype
In this study, we performed a meta-analysis of 70 protein lists from 20 studies to clarify the induction process of senescence. The analysis revealed the following points: I) The IGF and IGFBP signaling pathways are representative common factors in senescent cells. II) The RUNX1 and UCH deubiquitination that regulates proteasome activity were enriched at the very early stage (1-3 days). III) SASP of the middle stage and late stage were enriched inflammatory pathway related protein, including IL-1, IL-4, IL-12, IL-13, and NF-kb. IV) There is a change in carbohydrate metabolism towards glycolysis during senescence induction....
Source: Fight Aging! - October 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Mindful Body argues against mindlessly accepting age-related decline in cognition and health as inevitable
In 1979, Harvard researcher Ellen Langer invited elderly men to spend a week at a retreat designed to remind them of their younger days, surrounded by the art, music, food, games, décor, and more from the late 1950s. Afterward, the men were tested and found to have made significant gains in hearing, memory, dexterity, posture, and general well-being. It was as if being in a place signaling their younger days made them physiologically “younger.” Maybe you, too, have had an experience where your mind seemed to affect your health. It turns out there’s a reason for that, according to Langer, author of the new book The M...
Source: SharpBrains - October 9, 2023 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning anti-anxiety medication anti-depressants book cognition cognitive change cognitive-abilities Ellen Langer mind mindfulness-meditation mindlessly physiology placebo studies Th Source Type: blogs

Fight Aging! Newsletter, October 9th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 8, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Bonus Features – October 8, 2023 – 67% of Women are Having Issues with Getting a Clear Diagnosis – of which 25% are Still Waiting for Diagnosis or Gave up Entirely, Health Gorilla has 17 Healthcare Organizations Commit to Joining their QHIN, and More!
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News This year’s Customer Forum and Innovation Summit from Avel eCare will double as a celebration of their 30th anniversary! PEP Health’s AI-powered Patient Experience Platform releases its first report offering qua...
Source: EMR and HIPAA - October 8, 2023 Category: Information Technology Authors: Grayson Miller Tags: Healthcare IT 9amHealth Accelecom Amazon Web Services Artisight athenahealth Atropos Health Avel eCare AVIA Banner Health BJC Healthcare Boston Children's Hospital Children's Mercy Kansas City Cottage Health DrFirst Emma Smit Source Type: blogs

Towards More Selective Senolytic Drugs to Clear Senescent Cells from Aged Tissues
Cells enter a senescent state constantly throughout life, largely as a result of reaching the Hayflick limit on cellular replication, but also due to damage and stress. Senescent cells cease to replicate and begin to secrete pro-inflammatory, pro-growth signals. This attracts the immune system to sites of potential concern, and in the case of physical injuries to tissue the signaling of senescent cells helps to coordinate repair. Senescent cells are normally cleared from tissues fairly quickly, being destroyed either by immune cells, or via programmed cell death mechanisms. With age, however, the pace of clearance slows an...
Source: Fight Aging! - October 4, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The Dublin Longevity Declaration
Aubrey de Grey and Brian Kennedy are prominent scientists in the longevity community who take very different approaches to the problem of human aging. They recently collaborated to write the Dublin Longevity Declaration, now posted online and signed by some of the leading figures in the aging research field, as well as fellow travelers in the longevity industry, founders of biotech companies attempting to implement interventions to treat aging. We live in a world in which the opportunity to produce actual, real, working rejuvenation therapies exists, but too few people believe this to be true. There is too little funding d...
Source: Fight Aging! - October 3, 2023 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs