ConcertAI to Acquire CancerLinQ to Build the Leading Healthcare Learning and Research Network in Oncology
ConcertAI will Invest in CancerLinQ to Provide its Members with Upgraded Quality Reporting, Industry-Leading Real-World Data, and AI-Powered Solutions for Accelerated Clinical Trials in a Multi-Year Cooperation Agreement with ASCO  ConcertAI today announced the acquisition of CancerLinQ, previously a subsidiary of the American Society of Clinical Oncology (ASCO). In conjunction with the acquisition, ASCO will maintain a multi-year cooperation agreement with CancerLinQ. Building on CancerLinQ’s mission when launched by ASCO in 2013, this new venture will enhance and expand CancerLinQ’s use of real-world data, analytics...
Source: EMR and HIPAA - January 2, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT American Society of Clinical Oncology ASCO CancerLinQ Clifford A. Hudis ConcertAI Eric P. Winer Health IT Acquisitions Healthcare M&A Jeff Elton Source Type: blogs

Aptamers to Reduce Inflammatory AGE-RAGE Interaction
Researchers here discuss the use of aptamers that can bind to advanced glycation endproducts (AGEs). This prevents the AGEs from themselves binding to the receptor for AGEs (RAGE), an interaction that provokes inflammation. A sizable presence of circulating, short-lived AGEs is characteristic of the abnormal metabolism of obesity and obesity-related conditions such as type 2 diabetes. It is an open question as to how much of a contribution to the chronic inflammation of aging is provided by AGEs in people of a normal weight, eating a basically sensible diet, however. The only way to find out is to test a therapy of this na...
Source: Fight Aging! - January 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Should We Think of Rheumatoid Arthritis as an Age-Related Condition?
There are medical conditions that occur only in old age, and there are medical conditions, such as cancer, that can occur at any point in life, but more so in the old. Then there are grey area conditions that may occur to some greater degree in later life, or be worse in later life, but this is by no means widely appreciated. Where does the autoimmune condition of rheumatoid arthritis sit in this spectrum? Unlike cancer, it is not commonly thought of as an age-related disease, even though it is certainly affected and made worse by the processes of aging. This point is discussed in today's open access commentary and the pap...
Source: Fight Aging! - January 1, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Econoclasm continued: What's this pre-existing conditions deal?
Since I interrupted this series, I will remind you that previously, we discussed the problem of adverse selection -- that people who are unhealthy are more likely to buy health insurance in a hypothetical Free Market. ™ But sellers of health insurance must find ways of predicting and limiting their losses. The problem of adverse selection would not exist if we had a universal system, as all other wealthy countries and some not-so-wealthy do. Everybody would pay into the system, preferably according to their mea ns. That way people who are healthy today subsidize the costs for people who are not. If that strikes you as un...
Source: Stayin' Alive - January 1, 2024 Category: American Health Source Type: blogs

Collaboration between local oncologists and academia is crucial to closing the cancer care gap
There is undeniable hope and optimism when looking at the future of cancer care. Cancer survival rates are steadily rising as oncologists continue to learn more about the 100+ unique types of cancer—and emerging variants—that exist. Thanks to new targeted therapies and remarkable improvements in genomics, cancer care physicians and researchers are finding better ways Read more… Collaboration between local oncologists and academia is crucial to closing the cancer care gap originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 1, 2024 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

Fight Aging! Newsletter, January 1st 2024
Discussion of What is Need to Speed the Pace at which Drugs to Treat Aging Arrive in the Clinic Cellular Senescence in the Aging Brain, a Contributing Cause of Cognitive Decline Reviewing What is Known of the Mechanisms of Taurine Supplementation Relevant to Aging and Metabolism Blunt Thoughts on Calculating the Revealed Value of Human Life A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition Towards Adjustment of the Gut Microbiome to Slow Aging Gene Therapy Enhances Object Recognition Memory in Young and Old Mice Benefits of Sem...
Source: Fight Aging! - December 31, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition
The market has been in the doldrums and it has been a tough year for fundraising, both for non-profits and biotech startups. The conferences have exhibited more of an academic focus as companies tightened belts and postponed investment rounds, while investors stayed home. Not that this halts the flow of hype for some projects, and nor has it slowed media commentary on the longevity industry as it presently stands. A few of the articles in that commmentary are even interesting to read! The field has grown and is more mature now than has ever been the case. Biotech of all forms is a challenging field with a high failure rate...
Source: Fight Aging! - December 29, 2023 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs

What ’ s Special About AI Risks and Remedies in Health Care?
This article looks at what’s special about AI in health care, and some ways to address its needs. For this article, I spoke just to lawyers, because we’ve heard plenty from the technologists about AI’s potential and what they’re doing to minimize risk. The perspective of attorneys with an expertise in health care is illuminating. An anthology from STAT also contains some relevant analyses and case studies. Liability and Licensing Are clinicians facing the risk of lawsuits if they heed the advice of AI engines? Where do the new systems differ from older forms of clinical decision support—or the s...
Source: EMR and HIPAA - December 29, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT Hospital - Health System Regulations Security and Privacy Bard Berger Singerman LLP ChatGPT Erica Kraus FDA FDA AI Regulations Google Bard Healthcare AI Healthcare Source Type: blogs

Econoclasm Chapter Two, continued: " Insurance "
 Health insurance – again I’m using the term because everybody else does, not because I think it’s accurate – can work in many ways. One of the most important broad dimensions is how the benefit gets delivered. ·Indemnity plans are the most like fire insurance. They pay money when the beneficiary incurs medical expenses. (The money could be paid to the beneficiary, or directly to the provider. That doesn ’t much matter.)·Service benefit plans have negotiated arrangements with providers to pay them a certain amount for a given service, when it is provided.·Service delivery plans actually provide the s...
Source: Stayin' Alive - December 28, 2023 Category: American Health Source Type: blogs

Ring In the New Year With Basic Research
Empowering basic biomedical research, which focuses on understanding how living systems work, is one of NIGMS’ main goals. This type of research not only helps us learn how our bodies and those of other organisms function but also lays the foundation for advances in disease diagnosis, treatment, and prevention. We’re excited to see what the upcoming year has in store for the field! In preparation, we’re highlighting what NIGMS-supported scientists had to say in 2023 about the many merits of basic research. Also check out the links to the Biomedical Beat posts that feature them if you haven’t already. ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 27, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Scientific Process Source Type: blogs

From fear to empowerment: Beating breast lump anxiety [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Tami Burdick, a patient advocate and the author of Diagnosis Detective: Curing Granulomatous Mastitis. Tami shares her personal journey with granulomatous mastitis (GM) and how she navigated the fear of a breast lump. Discover the relationship between GM and breast cancer risk, practical Read more… From fear to empowerment: Beating breast lump anxiety [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 27, 2023 Category: General Medicine Authors: Tags: Podcast Oncology/Hematology Source Type: blogs

Cellular Senescence in the Aging Brain, a Contributing Cause of Cognitive Decline
Senescent cells are created throughout the body at all stages of life, largely when somatic cells reach the Hayflick limit on replication. Senescent cells cease replication and begin to energetically produce pro-growth, pro-inflammatory factors, attracting the attention of the immune system and otherwise changing the behavior of surrounding cells. Cell stress and mutational damage can induce senescence, and in this case senescence is a mechanism that acts to limit the risk of cancer. Tissue injury also produces senescent cells, and here they help to coordinate the activities of the many different cell types that become inv...
Source: Fight Aging! - December 26, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Benefits of Semaglutide in Heart Failure are not Just Due to Weight Loss, in Mice at Least
This study investigated semaglutide, a glucagon-like peptide-1 receptor agonist that induces significant weight loss in patients with obesity and/or type 2 diabetes mellitus and has been associated with improved cardiovascular outcomes. In a mouse model of HFpEF that was caused by advanced aging, female sex, obesity, and type 2 diabetes mellitus, semaglutide, compared with weight loss induced by pair feeding, improved the cardiometabolic profile, cardiac structure, and cardiac function. Mechanistically, transcriptomic, and proteomic analyses revealed that semaglutide improved left ventricular cytoskeleton function a...
Source: Fight Aging! - December 26, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Uncovering the truth behind my father ’ s tragic end
I was the “stranger” at my father’s bedside. Shortly after his 84th birthday, my father fell and landed in the hospital with a split scalp. His metastatic prostate cancer was an incidental finding, and superimposing this wildly invasive tumor on his Parkinson’s-compromised body marked his first steps onto his death path. I came to my Read more… Uncovering the truth behind my father’s tragic end originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 24, 2023 Category: General Medicine Authors: Tags: Conditions Palliative Care Source Type: blogs

Bonus Features – December 24 , 2023 – 74% of orgs automating RCM operations, per-physician revenue exceeding expenses at U.S. hospitals, plus 19 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Studies Median hospital margins rose to 2% in November, according to the latest data from Syntellis, and per-physician revenue growth is outpacing per-physician expenses. Nearly 3 in 4 (74%) healthcare organizations ar...
Source: EMR and HIPAA - December 24, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Accelecom Akasa Avel eCare Ayble Health Boston Children's Hospital Brightside Health Butterfly Network Cancer Moonshot Clarify Health Commure Engage Data Dimensions Digital Medicine Society Greenway Health Healthc Source Type: blogs