Will Cancer Drugs Ever Be As Affordable As Retrovirals in Developing Countries?
By ASHLEY ANDREOU
In 2014, the majority of international health aid was dedicated to HIV. So, one might reasonably assume that this is the largest health problem facing the world. Yet, HIV only constitutes 4% of the global burden of disease. In 2014, noncommunicable diseases (NCDs) made up 50% of the entire disease burden, but only received 2% of all global health funds.
The disease burden of NCDs is fast outpacing that of infectious diseases. Despite this, the proportion of global health financing dedicated to combatting NCDs has remained constant over the past 15 years at 1 to 2%.
Currently, 32.6 million individuals are...
Source: The Health Care Blog - May 17, 2018 Category: Consumer Health News Authors: Matthew Holt Tags: OP-ED Biologic generics Cancer Pharmaceuitcals Retrovirals Source Type: blogs
Will Cancer Drugs Ever Be As Affordable As Retrovirals in Low and Middle Income Countries?
By ASHLEY ANDREOU
In 2014, the majority of international health aid was dedicated to HIV. So, one might reasonably assume that this is the largest health problem facing the world. Yet, HIV only constitutes 4% of the global burden of disease. In 2014, noncommunicable diseases (NCDs) made up 50% of the entire disease burden, but only received 2% of all global health funds.
The disease burden of NCDs is fast outpacing that of infectious diseases. Despite this, the proportion of global health financing dedicated to combatting NCDs has remained constant over the past 15 years at 1 to 2%.
Currently, 32.6 million individuals are...
Source: The Health Care Blog - May 17, 2018 Category: Consumer Health News Authors: Matthew Holt Tags: OP-ED Biologic generics Cancer Pharmaceuitcals Retrovirals Source Type: blogs
New At-Home Lab Testing Device Provides CBC Counts for Cancer Patients
I have been closely tracking the development of new at-home lab testing devices because I think, accompanied by expanded telemedicine choices, the face of healthcare will be changed forever. A recent article inDark Daily announced such a device for complete blood counts (CBC) (see:New At-Home CBC Device Enables Complete Blood Testing for Cancer Treatments and Biological/Viral Monitoring). Below is an excerpt from it:.....[N]ew devices that enable chronic disease patients to monitor and report findings to care providers continue to be developed and embraced by healthcare consumers. One such device fromAthelas, a diagn...
Source: Lab Soft News - May 15, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Industry News Clinical Lab Testing Cost of Healthcare Food and Drug Administration Healthcare Information Technology Lab Industry Trends Lab Processes and Procedures Medical Consumerism Point-of-Care Testing Test Kits and Ho Source Type: blogs
Fight Aging! Newsletter, April 2nd 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - April 1, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A mix of treatments may extend life for men with aggressive prostate cancer
For men diagnosed with aggressive cancer that’s confined to the prostate and nearby tissues, the overarching goal of treatment is to keep the disease from spreading (or metastasizing) in the body. Doctors can treat these men with localized therapies, such as surgery and different types of radiation that target the prostate directly. And they can also give systemic treatments that kill off rogue cancer cells in the bloodstream. Hormonal therapy, for instance, is a systemic treatment that kills prostate cancer cells by depriving them of testosterone, which fuels their growth.
Now a new study shows that a mix of different t...
Source: Harvard Health Blog - March 31, 2018 Category: Consumer Health News Authors: Charlie Schmidt Tags: Cancer Men's Health Prostate Health Source Type: blogs
The Rise of Oisin Biotechnologies
This recent interview with Gary Hudson of Oisin Biotechnologies covers a range of topics; there is a lot more to it than is quoted here. The company is working on the application of a programmable gene therapy to the targeted destruction of senescent and cancerous cells. Since the approach can be adjusted to kill cells that express significant amounts of any arbitrarily selected target protein, it can in principle be adapted to destroy other types of unwanted cell. The immune system in older individuals or patients with autoimmune diseases, for example, contains any number of problem cells that it would be beneficial to re...
Source: Fight Aging! - March 29, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
A Short Report from the Undoing Aging Conference
The LongLongLife team here reports briefly on their time at the recent Undoing Aging conference. This was the first in a series of conferences, hosted jointly by the SENS Research Foundation and Forever Healthy Foundation, that will mix the scientific and academic focus of the SENS rejuvenation research conferences with the biotechnology industry focus of the Rejuvenation Biotechnology conferences. By all accounts the initial Undoing Aging event was well received.
The very first Undoing Aging Congress was held in March 2018 in Berlin, and was attended by 350 people from a total of 36 countries. Initiated by Aubrey...
Source: Fight Aging! - March 26, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, March 19th 2018
In this study, we did not observe significant age-dependent upregulation of the prominent SASP cytokine Il6 in any tissue, although an upward trend was observed that was consistent in magnitude with previous observations in the heart and kidney. This modest age-related upward trend could be explained by a previous report which demonstrated that senescent cell-secreted IL-6 acts in an autocrine manner, reinforcing the senescent state, rather than inducing senescence or promoting dysfunction in neighboring cells.
The decreased expression of Il6 with age we observed in the hypothalamus could be indicative of a lack or ...
Source: Fight Aging! - March 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Undoing Aging: An Interview with Aubrey de Grey
The Undoing Aging conference in Berlin is presently underway, a gathering of everyone who is anyone in the rejuvenation research community. It is hosted jointly by the SENS Research Foundation and the Forever Healthy Foundation, and is a unification of the varied themes of the past fifteen years of SENS conferences: the science of aging and its treatment from the earlier SENS conference series mixed with the industry, startup, and commercial development focus of the Rejuvenation Biotechnology series of recent years.
The first rejuvenation therapies to be implemented and shown to work, those based on clearance of sen...
Source: Fight Aging! - March 16, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Paligenosis as a Potential Source of Methods to Target Many Types of Cancer with One Type of Therapy
The future of the treatment of cancer will be, must be, dominated by classes of therapy that can be easily and cost-effective applied to many different types of cancer. Such therapies can only exist as a result of targeting mechanisms that are shared by many or all types of cancer. It must also be challenging or impossible for cancerous cells to do without these mechanisms. The biggest issue in cancer research over the past few decades, in my opinion, is the specificity of therapies, the amount of time and resources poured into efforts to produce treatments that can only work on one type or a few types of cancer, and that ...
Source: Fight Aging! - February 27, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, February 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - February 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Machine Learning for Building Personalized Cancer Nanomedicines: Interview with Dr. Daniel Heller
Dan Heller
Researchers at the Sloan Kettering Institute and the Weill Cornell Graduate School of Medical Sciences in New York have developed a machine learning approach to design personalized nanoparticle therapies for cancer.
Personalized cancer therapies aim to provide a treatment that is tailored to the genetic makeup of a patient’s tumor. They can still cause side effects, however, when they accumulate in certain off-target tissues. Nanoparticles can help to increase drug accumulation in the tumor, and reduce off-target tissue exposure, helping to increase drug effectiveness and reduce side effects.
This research tea...
Source: Medgadget - February 15, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Nanomedicine Oncology Source Type: blogs
Weaponizing the Biochemistry of Huntington's Disease as a General Cancer Therapy
An interesting observation that has arisen over the years of epidemiological study of human age-related disease is that there are a number of distinct inverse relationships between incidence of cancer and incidence of some forms of neurodegeneration. This was in the news a few years ago in the case of Alzheimer's disease for example. Why would people with a higher risk of cancer suffer lower rates of Alzheimer's disease, however? We can only speculate at this point, but the more recent discovery I'll point out here adds fuel for that speculation. The Alzheimer's-cancer relationship is modest in size and somewhat complex in...
Source: Fight Aging! - February 14, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
There are Many Possible Paths to Immunotherapy for Senescent Cell Destruction
Rising numbers of senescent cells are one of the root causes of aging, a process that arises from the normal operation of youthful metabolism, yet results in accumulated damage and failure over time. Senescent cells generate signaling that degrades tissue function, breaks down and remodels tissue structure, spurs chronic inflammation, and alters the behavior of surrounding cells for the worse. Evidence shows their presence to be a contributing cause of a range of common fatal age-related conditions. In a youthful body, near all cells that become senescent and fail to self-destruct as a result are promptly eliminated by the...
Source: Fight Aging! - February 12, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
An Impressive Performance in Clearing Cancer from Mice via Immunotherapy
Immunotherapy is a cut above chemotherapy and radiotherapy: at its best, it is significantly more effective and significantly less harmful to the patient. It has still required years, a great deal of funding, and many failures for those best approaches to arise. Nonetheless, the report here is a cheering example for the sizable fraction of us expected to suffer cancer at some point in the years ahead if the condition is not soon brought under medical control. This immunotherapy appears highly effective, and just importantly, adaptable to many types of cancer. This potential for broad application is the most important aspec...
Source: Fight Aging! - February 2, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
