Fight Aging! Newsletter, March 4th 2024
In conclusion, HSV (but not CMV) infection may be indicative of doubled dementia risk.
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Increased Dietary Leucine Activates mTOR Signaling in Macrophages, Accelerating Atherosclerosis
https://www.fightaging.org/archives/2024/02/increased-dietary-leucine-activates-mtor-signaling-in-macrophages-accelerating-atherosclerosis/
Leucine is an essential amino acid, only obtained from the diet rather than synthesized by our cells. Leucine supplementation has been proposed as a way to slow the loss of muscle mass with age, as leucine processing becomes dysregulated with aging in a way...
Source: Fight Aging! - March 3, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Telemedicine ’ s impact on lifespan and cancer eradication
Forty years ago when I first started in medicine, there were no CT scans or MRIs. In the next forty years, I foresee cancer as an illness of the past, and life expectancy will be over one hundred years old. Scientific advancements will push medicine ahead, improving quality of life in increments, slowly taking two
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Telemedicine’s impact on lifespan and cancer eradication originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 2, 2024 Category: General Medicine Authors: Gene Uzawa Dorio, MD Tags: Tech Health IT Source Type: blogs
What is Known of the Contribution of Cellular Senescence to Osteoporosis
The vast majority of senescent cells are produced when somatic cells reach the Hayflick limit to cell division, their telomeres shortened to a point at which they either self-destruct or enter the senescent state. Damage due to mutation or cytotoxic compounds can also induce senescence, as can the regenerative processes following injury. Senescent cells cease replication, become larger, and change their behavior in many other ways. Senescent cells secrete a pro-growth, pro-inflammatory mix of signals, the senescence-associated secretory phenotype (SASP), that attracts the attention of immune cells capable of destroying sen...
Source: Fight Aging! - March 1, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
It is literally possible to be a woman in medicine! We are doing it every day.
I love America Ferrara’s monologue in Barbie. Similarly, the impossibility of being a woman in medicine, as so clearly stated in Dr. Jennifer Lycette’s recent essay in KevinMD, absolutely resonates with me. And yet, let’s not forget that in 2021, two of five practicing physicians were women, with certain fields including (my own) dermatology, internal medicine, and pediatrics having a
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It is literally possible to be a woman in medicine! We are doing it every day. originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 1, 2024 Category: General Medicine Authors: Christine J. Ko, MD Tags: Physician Dermatology Oncology/Hematology Source Type: blogs
From Afghanistan to hope: a cancer patient ’ s remarkable story
A few weeks back, a young male from Afghanistan visited us in the oncology clinic. He was in his late 20s and came with a translator to facilitate his consultation. He was not very fluent in either Urdu or English but could still understand most of it. He seemed very anxious and perplexed in the
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From Afghanistan to hope: a cancer patient’s remarkable story originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 1, 2024 Category: General Medicine Authors: Dr. Damane Zehra Tags: Conditions Oncology/Hematology Source Type: blogs
Heart-stopping brain surgery: a surgeon ’ s harrowing dilemma
An excerpt from of Paint and Pancakes. The epicenter of Jane’s cancer occupied some very expensive real estate between Broca’s area and the motor strip. Her ability to speak and form coherent words resided in Broca’s. A little further back was the Motor Strip, which controlled the movement of the right side of her body.
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Heart-stopping brain surgery: a surgeon’s harrowing dilemma originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 29, 2024 Category: General Medicine Authors: Marc Arginteanu, MD Tags: Conditions Surgery Source Type: blogs
Aged Pancreatic Fibroblasts Secrete GDF-15, Encouraging Tumor Growth
Researchers here note one of a broad range of examples in which age-related changes in the state and behavior of non-cancerous cells results in a more hospitable environment for the growth of neighboring cancerous tissue. Cancer is an age-related condition not just because of increased damage to cells in older tissues, nor just because the immune system falters in its surveillance of potentially cancerous cells, but also due to other maladaptive changes that favor the metabolism and growth of some forms of cancerous cells.
A new study provides clues as to why pancreatic cancer is more common and aggressive in olde...
Source: Fight Aging! - February 28, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
MDM2 Inhibition Reduces Loss of Synapses in a Cell Culture Model
Loss of synaptic connections between neurons is one of the harmful outcomes of neurodegenerative conditions such as Alzheimer's disease. In mouse models of Alzheimer's disease engineered to produce amyloid-β, excessive pruning of synapses is thought to be a maladaptive response to the presence of misfolded amyloid-β. Investigating the details of this excessive pruning in cell cultures, researchers have found a way to interfere in the signaling involved. At least in vitro there are positive results, but it remains to be seen as to how well this approach will work in the animal models of Alzheimer's disease.
Resea...
Source: Fight Aging! - February 28, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Bonus Features, ViVE Edition – February 27, 2024 – GE and Biofourmis collaborating on care at home, DeepScribe and AWS Health Scribe partnering, plus 20 other stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
This edition is a special dispatch from the first days of ViVE 2024. There have been a lot of new research reports, products, and partnerships announced in Los Angeles. We wanted to try and cover as many announcements for the He...
Source: EMR and HIPAA - February 27, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 2morrow AvaSure AWS HealthScribe Axil Health Biofourmis Cancer Moonshot CenTrak Clearstep Health Coeus Health CPSI DeepScribe Dolbey Froedtert & the Medical College of Wisconsin GE Healthcare Healthcare IT Today Source Type: blogs
Hamilton Beach Brands Holding Company Announces Acquisition of HealthBeacon PLC
Hamilton Beach Brands Holding Company today announced that, through its Hamilton Beach Health subsidiary, it has acquired HealthBeacon PLC, a medical technology firm and strategic partner of the company. HealthBeacon develops connected devices that enable patients with chronic conditions to manage their injectable medication regimens at home and provides other health services.
Gregory H. Trepp, President and Chief Executive Officer at Hamilton Beach Brands Holding Company, said, “This acquisition is a key step in support of our strategic initiative to expand in the fast-growing home health and wellness market, and it...
Source: EMR and HIPAA - February 27, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Gregory H. Trepp Hamilton Beach Brands Holding Company Hamilton Beach Health Health IT Acquisitions HealthBeacon PLC Healthcare M&A Kieran Daly Rob George Source Type: blogs
Repeated Cycles of a Fasting-Mimicking Diet Reduce Measures of Biological Age
We report on the secondary outcome measures of the FMD-trial (NCT02158897) which are biomarkers associated with aging or age-related diseases, and metabolic syndrome, including visceral and hepatic fat, lymphoid/myeloid ratios, and blood markers, which were not investigated in the original report.
We show that 3 FMD cycles in adult study participants are associated with reduced insulin resistance and other pre-diabetes markers, lower hepatic fat (as determined by magnetic resonance imaging), and increased lymphoid to myeloid ratio, an indicator of immune system age. Based on the Klemera-Doubal measure of biological a...
Source: Fight Aging! - February 27, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Telomere Length as a Target for Therapy
Average telomere length in a tissue is some reflection of (a) stem cell activity and (b) pace of cell division. Telomeres, repeated DNA sequences at the ends of chromosomes, lose some of their length with each cell division, and cells self-destruct or become senescent when telomeres become too short. This limits the ability of somatic cells to replicate, reducing the odds that a given cell will mutate to become cancerous by imposing a limit on cell activity and cell life span, enforcing turnover of cells in tissues. Stem cells, in comparison, are a small, well protected, privileged set of cell populations that use telomera...
Source: Fight Aging! - February 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Bonus Features – February 25, 2024 – 73% of digital health vendors use FHIR APIs, 83% of clinicians think telemedicine is good for chronic condition management, plus 28 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
U.S. Reps Mike Kelly (R-PA) and Bill Foster (D-IL) introduced the Patient Matching and Transparency in Certified Health IT (MATCH IT) Act of 2024, which would standardize the way demographic information is entered into cer...
Source: EMR and HIPAA - February 25, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Accenture Authenticx Availity AXYS Biofourmis Brightside Health Dandelion Health Digital Health Collaborative Edifecs EHR Association Experity FHIR API Healthcare IT Today Bonus Features Healthcare Legislation H Source Type: blogs
The power of empathy: a tale of two prostate biopsies
I’m sitting in a windowless room in the hospital’s urology department waiting for my second prostate biopsy, feeling surprisingly calm and relaxed. It’s a surveillance biopsy. Two years ago, the first one revealed “a few scattered cancer cells” while zeroing in on what turned out to be a harmless nodule. I’d learned then that a
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The power of empathy: a tale of two prostate biopsies originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 25, 2024 Category: General Medicine Authors: Scott Janssen, MSW, LCSW Tags: Conditions Urology Source Type: blogs
The power of empathy: a tale of 2 prostate biopsies
I’m sitting in a windowless room in the hospital’s urology department waiting for my second prostate biopsy, feeling surprisingly calm and relaxed. It’s a surveillance biopsy. Two years ago, the first one revealed “a few scattered cancer cells” while zeroing in on what turned out to be a harmless nodule. I’d learned then that a
Read more…
The power of empathy: a tale of 2 prostate biopsies originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 25, 2024 Category: General Medicine Authors: Scott Janssen, MSW, LCSW Tags: Conditions Urology Source Type: blogs
