What Do We Need To Have AI-Equipped Nanobots In Medicine
Disease, noun [archaic]: A historical term used to describe various physical and mental ailments that affected organisms, primarily humans, in an era before the advent of comprehensive nanomedical and genetic interventions. In the technologically primitive past, diseases were common causes of discomfort, dysfunction, and mortality, often requiring medical treatment and care. Modern advances and nanobots in medicine have rendered this term obsolete, as conditions previously classified as diseases are now either preventable or entirely curable at the molecular level. Are we on the brink of a brave new world where disease...
Source: The Medical Futurist - November 30, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Nanotechnology nanobots nanobots in medicine AI Source Type: blogs

Applying Proteomics to the Development of Senolytic Therapies
We describe the technological advancements that have enabled researchers to address challenges inherent to the proteomic analysis of blood, such as the wide dynamic range of protein concentrations, and discuss multiple workflows that can be leveraged for the discovery of senescence biomarkers, senolytic targets, and cell-surface proteins. We also highlight how modern mass spectrometry-based technologies will open the door for future clinical applications, develop translationally relevant approaches to quantify aging and cellular senescence, and develop therapeutics for enhancing human healthspan. (Source: Fight Aging!)
Source: Fight Aging! - November 27, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Bonus Features – November 26, 2023 – 85% of healthcare orgs boosting IT spending in 2024, 70% of orgs actively considering generative AI, plus 18 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Studies The latest Hospital Vitals report from Syntellis and the AHA found that hospitals have seen a 28% decline in cash reserves over the last 19 months. This is due in large part to increased expenses (from 25$ for...
Source: EMR and HIPAA - November 26, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Aerin Medical Akasa American Hospital Association Artera AvaSure BrightSpring Health Services CancerIQ Carestream Health Clue CodaMetrix Da Vinci Project Derrick Sung eHealth Exchange EHR Association First Healt Source Type: blogs

The hidden danger of prolonged gaming
A couple of weeks ago, my sister texted me that my 26-year-old nephew Justin was complaining that his chest hurt every time he breathed in. Justin is a healthy, athletic guy who played soccer throughout high school and volleyball in college. More recently, while living back home job hunting after finishing a master’s degree in Read more… The hidden danger of prolonged gaming originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 25, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

A Novel Mitophagy Inducing Compound
A sizable fraction of research aimed at treating aging involves screening natural compounds in search of those that can modestly slow aging in short-lived animal models. This is because the economics of developing such a compound into a drug or supplement are well understood by investors, and because it dovetails well with the scientific goal of increased understanding of how aging progresses at the level of cellular biochemistry, rather than because it is going to make a big difference for patients. If sizable gains in healthy life span were the driving incentive, the field would look very different, and the emphasis woul...
Source: Fight Aging! - November 24, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Learning from Laron Syndrome
The longest lived mice are still those engineered to lack functional growth hormone or growth hormone receptor. That record was established more than 20 years ago, and remains in place even as an energetic research and development community focused on treating aging as a medical condition has come into being. In part this is the case because research has largely focused on approaches known to produce lesser effects on aging in mice, such as the discovery of small molecules that mimic portions of the calorie restriction response. In part it is because the pace of development in the life sciences is ever slower than we would...
Source: Fight Aging! - November 23, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

AL Myeloma/ Cardiac Amyloidosis
A dear friend of mine, whom I met via the blog many years ago, has been dealing with an unusual and very serious condition for several months. She asked if she could post an appeal on the blog to see if anybody else has had a similar experience or can help her in any way. If you have any information that might be useful to Clare in this very difficult moment, please let me know, or leave a comment on this post. If you want your comment to remain private, I will definitely respect your wish and send it only to Clare. Thank you very much. Here is what she wrote: I’ve had smouldering Myeloma for 13 years without treatm...
Source: Margaret's Corner - November 23, 2023 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll amyloid deposits in heart amyloid myeloma Source Type: blogs

This Is Good News About A Cancer None Of Us Ever Want!
 I, for one, would leap at an annual blood test to avoid this horror! Scientists to develop first ever blood test for pancreatic cancer By Joanna Panagopoulos 10:15PM November 16, 2023 Australian researchers are close to developing the first blood test for the “silent killer” pancreatic can cer. Scientists from the Walter and Eliza Hall Institute of Medical Research in Melbourne believe a (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - November 22, 2023 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

An Aging Clock Derived from Images of the Lens of the Eye
In this study, we used informative lens photographs to generate LensAge as an innovative indicator to reveal aging status of lens based on deep learning (DL) models. Under ideal physiological conditions (both genetic and environmental), biological age should be synchronized with chronological age. While in reality, there are almost always differences between biological age and chronological age, which is considered to result from individually different aging processes. Therefore, we measured the difference between LensAge and chronological age as the LensAge index to assess an individual's aging rate relative to peers, and...
Source: Fight Aging! - November 22, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

A resident ’ s critical discovery: Advanced cancer unveiled
It was my first week in the radiation oncology department as a resident. The day had been busy, and most of the consultants and staff had already left the outpatient department (OPD). I was exhausted and famished, with thoughts of dinner dominating my mind. Just as I was beginning to wind down, the physician assistant Read more… A resident’s critical discovery: Advanced cancer unveiled originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 22, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

Assessing Pentadecanoic Acid In Vitro
The work on pentadecanoic acid noted here is interesting, but should be taken with a grain of salt given that it is performed in vitro. In general, one should expect any given set of mechanisms in the cell to be associated with many different means of manipulation. It is interesting to see a fatty acid capable of touching on the same mechanisms as rapamycin, but remember that the ability to influence the same mechanistic targets does not necessarily translate to the same ability to produce a modest slowing of aging in animal studies. So the usual advice stands here, to wait for the animal studies before getting too excited...
Source: Fight Aging! - November 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Some Cancers Induce Cellular Senescence to Aid in Growth
The presence of senescent cells can make a tissue environment more hospitable for cancer, as senescent cells secrete growth factors in addition to pro-inflammatory signals. Researchers have provided evidence for some cancers to aggressively employ the strategy of inducing senescence. Here, a research group notes that this induction of senescence can act to suppress the local immune response to a cancer by co-opting immune cells, making them senescent. It remains an open question as to whether targeting senescent cells for destruction is a good idea in the early stages of a cancer, rather than leaving them in place to attra...
Source: Fight Aging! - November 21, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Common Signs Of Vitamin D Deficiency
Vitamin D supplementation could lower the risk of dying from cancer-related diseases and increase life expectancy by years. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 20, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Nutrition Source Type: blogs

Bonus Features – November 19, 2023 – Critical access hospitals 16% less likely to participate in data exchange, two-thirds of orgs plan to increase AI spending by 25% in the next three years, plus 36 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News Three U.S. Representatives have introduced the WEAR IT Act, which would let Americans use money from Flexible Spending Accounts or Health Savings Accounts to pay for devices such as blood glucose and EKG monitors or sleep ...
Source: EMR and HIPAA - November 19, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AccurKardia Aiberry Artisight Availity Avel eCare Azalea Health Bamboo Health BAMF Health BioIntelliSense CentralReach CHIME Fall Forum Circular Doccla Edifecs Equality Health Garrett Goldberg GE Healthcare Source Type: blogs

Fight Aging! Newsletter, November 20th 2023
In this study, we attempted to further explain the role, exact mechanism and target of ICA in treating AD from the ferroptosis perspective. We found that ICA could improve the neurobehavioral, memory, and motor abilities of AD mice. It could lower the ferroptosis level and enhance the resistance to oxidative stress. After inhibition of MDM2, ICA could no longer improve the cognitive ability of AD mice, nor could it further inhibit ferroptosis. Network pharmacological analysis revealed that MDM2 might be the target of ICA action. « Back to Top Particulate Air Pollution and Its Effects on the Mechan...
Source: Fight Aging! - November 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs