Empowering Pakistani women: Surviving cancer and challenging traditional norms
We have a female patient admitted to our oncology ward for a week. I’ve known her for a long time. She works in our hospital’s dental department as a technologist. She is currently 40 years old. She was diagnosed with a brain tumor in 2009. She underwent maximum safe resection; it was oligodendroglioma grade 3. Read more… Empowering Pakistani women: Surviving cancer and challenging traditional norms originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 9, 2024 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

IL-15 Improves the Ability of Natural Killer Cells to Attack Cancerous Tissue
Cancerous tissue co-opts the immune system, suppressing its ability to destroy cancerous cells, and even gaining the assistance of immune cells in encouraging the growth of a tumor. There are many different mechanisms by which this happens, varied by immune cell type and form of cancer, comparatively few of which are well mapped and well understood. The active and well-funded cancer research community continues to explore the potential to interfere in these harmful interactions between cancer and immune system. The approach noted here is one of many, and typical of this sort of research program in that it targets a specifi...
Source: Fight Aging! - February 9, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Death of Death, in English
The authors of the Death of Death are regulars on the conference circuit for aging research, the longevity industry, and patient advocacy for the treatment of aging as a medical condition. The book was originally in Spanish, and has finally been translated into English. It is a popular science overview of progress towards technologies that will first slow aging, then enable the control of aging, and eventually, at some point, produce large gains in healthy human life span, postponing death by aging essentially indefinitely. The book and its authors also unapologetically and straightforwardly stand in opposition to the horr...
Source: Fight Aging! - February 8, 2024 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

Hackers, Breaches And The Value Of Health Data: 2024 E-Book Update
As solutions like remote care are becoming the norm, 3D printing disrupts the normal supply chain and the number of life science studies on tools like artificial intelligence (AI) skyrocket, it’s become clear that we are not anticipating the digital health era; we are in the digital health era. This was to come sooner or later, but the pandemic accelerated the process by years. However, along with the enhanced healthcare landscape that digital health brings along, there is the pressing issue of privacy. To put it bluntly, there is no digital health without sacrificing a part of our privacy. The advanced technolo...
Source: The Medical Futurist - February 8, 2024 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine Health Sensors & Trackers Healthcare Policy Security & Privacy facebook data privacy google data security deepmind EHR Hospital cybersecurity genetic sequencing smartphone data breach big t Source Type: blogs

Who to Blame for Health Costs: The Poisoned Chalice of “ Moral Hazard ”
By JEFF GOLDSMITH How the Search for Perfect Markets has Damaged Health Policy Sometimes ideas in healthcare are so powerful that they haunt us for generations even though their link to the real world we all live in is tenuous. The idea of “moral hazard” is one of these ideas.   In 1963, future Nobel Laureate economist Kenneth Arrow wrote an influential essay about the applicability of market principles to medicine entitled “Uncertainty and the Welfare Economics of Medical Care”.     One problem Arrow mentioned in this essay was “moral hazard”- the enhancement of demand for something people us...
Source: The Health Care Blog - February 8, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Health Care Costs Jeff Goldsmith Kenneth Arrow Medicare Moral Hazard Source Type: blogs

Advocating for Epigenetic Reprogramming as a Potential Rejuvenation Therapy
Partial epigenetic reprogramming emerges from the intersection of understanding how cells behave in cancerous tissue and during embryonic development. In the developing embryo there is a point at which adult germline cells convert themselves into embryonic stem cells, discarding forms of damage and dysfunction characteristic of adult cells and restoring a youthful pattern of the epigenetic markers attached to the genome that control its shape in the cell nucleus and thus gene expression. Some of the genes involved are known to also operate in cancers, in which replication and reprogramming runs wild, but which use many of ...
Source: Fight Aging! - February 6, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Will Patients Have To Pay For Using AI In Their Healthcare?
This article discussed how the author was asked if she wanted to pay $40 extra for additional AI analysis in mammography. In her case a Manhattan radiology clinic offered an AI analysis of their mammogram for an additional $40, not covered by insurance. This scenario was echoed at a clinic in suburban Baltimore, where patients were similarly offered AI-assisted mammography for a $40 fee. These instances mark the initial real-world applications of AI in patient care but also introduce new factors to the healthcare equation.  To make things more complicated, we can’t look for a single, universal solution here. Heal...
Source: The Medical Futurist - February 6, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine AI in healthcare AI in medicine Source Type: blogs

Hope, healing, and challenges in eating disorder recovery [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Jillian Rigert, an oral medicine specialist and radiation oncology research fellow. In this episode, we delve into the world of eating disorders, drawing from Jillian’s unique perspective as both a patient and a health care professional. We explore topics such as maintaining hope Read more… Hope, healing, and challenges in eating disorder recovery [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 6, 2024 Category: General Medicine Authors: Tags: Podcast Obesity Source Type: blogs

The Money ’ s in the Wrong Place. How to Fund Primary Care
By MATTHEW HOLT I was invited on the Health Tech Talk Show by Kat McDavitt and Lisa Bari and I kinda ranted (go to 37.16 here) about why we don’t have primary care, and where we should find the money to fix it. I finally got around to writing it up. It’s a rant but a rant with a point! We’re spending way too much money on stuff that is the wrong thing. 30 years ago, I was taught that we were going to have universal health care reform. And then we were going to have capitated at-risk entities. then below that, you have all these tech enabled services, which are going to make all this stuff work an...
Source: The Health Care Blog - February 5, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Matthew Holt ACA ACO CVS FQHCs Health Systems hedge funds Hospitals Medisync primary care Walgreens Walmart Source Type: blogs

poem
 Winter BreakAfter the end of year holiday rushWhen nothing is ever enoughNo matter how muchYou think you have given,When innocence is negligence,Extravagance forgets its shameAnd the long con unravelsInto scraps of New Year ’s Eve confetti,We come to the southern beach Ostensibly to be refreshed By the predictableCrashing of waves against a wetGraveyard of broken bones, wavesThat flatten like black tongues And retreat with seized Fragments of old shieldsCeded by soft bodiesForever lost.It ’s too cold in January, even down Here just north of the Tropic of Cancer.We ’re wearing sweaters a...
Source: Buckeye Surgeon - February 5, 2024 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs

Fight Aging! Newsletter, February 5th 2024
In conclusion, the Immunity and Redox Clocks allow BA quantification in mice and both the ImmunolAge and RedoxAge in mice relate to lifespan. « Back to Top Senolytic CAR T Cell Therapy Improves Health in Aged Mice https://www.fightaging.org/archives/2024/01/senolytic-car-t-cell-therapy-improves-health-in-aged-mice/ To the degree that senescent cells in a tissue exhibit distinctive surface features, one can deploy technologies such as chimeric antigen receptor T cells to selectively destroy them. T cells will destroy whatever cell binds to the chimeric antigen receptor they are equipped w...
Source: Fight Aging! - February 4, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Gene therapy breakthroughs: a new era in genetic disorder treatment
In a significant leap forward for medical science, recent breakthroughs in gene therapy are ushering in a new era of treatment for various human diseases. The field of gene therapy, which involves manipulating or introducing genetic material into a person’s cells to treat or prevent disease, has seen remarkable advancements, with several gene therapy drugs Read more… Gene therapy breakthroughs: a new era in genetic disorder treatment originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 4, 2024 Category: General Medicine Authors: Tags: Meds Oncology/Hematology Source Type: blogs

The hand from behind the curtain
It has been almost two decades since I worked at this hospital. This is where I grew up as a physician. After my home, I have spent most of my life within these walls and walking these hallways. The hospital used to have two main buildings, but a few years ago, the administration decided to Read more… The hand from behind the curtain originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 3, 2024 Category: General Medicine Authors: Tags: Physician Oncology/Hematology Source Type: blogs

Making a Mouse that Exhibits Human Telomere Dynamics
Telomerase acts to extend telomeres, the repeated DNA sequences at the ends of chromosomes. With every cell division, some of the telomere repeats are lost. Cells with critically short telomeres become senescent or undergo programmed cell death, having reached the Hayflick limit on replication. Some cells employ telomerase to adjust the countdown of telomere length. In humans, only stem cells use telomerase. In other species, such as mice, telomerase is much more widely expressed. There has been some interest in the research community in upregulation of telomerase as a way to improve stem cell and tissue function in old ag...
Source: Fight Aging! - February 2, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

What films get wrong about cancer – and why it matters
There are more cancer types than there are organ systems, but, according to Hollywood, there is essentially just “Cancer.” Capital C. Period. Cancer-inflicted characters on the silver screen also primarily face just one outcome: death. This usually follows a montage of chemotherapy treatments that leave movie stars bald and purple under the eyes. There is Read more… What films get wrong about cancer – and why it matters originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 2, 2024 Category: General Medicine Authors: Tags: Physician Oncology/Hematology Source Type: blogs