Fight Aging! Newsletter, October 15th 2018
This study suggests that exocrine glands can be induced from pluripotent stem cells for organ replacement regenerative therapy.
Replacement of Aged Microglia Partially Reverses Cognitive Decline in Mice
https://www.fightaging.org/archives/2018/10/replacement-of-aged-microglia-partially-reverses-cognitive-decline-in-mice/
Researchers here report on a compelling demonstration that shows the degree to which dysfunctional microglia contribute to age-related neurodegeneration. The scientists use a pharmacological approach to greatly deplete the microglial population and then allow it to recover naturally. Th...
Source: Fight Aging! - October 14, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Few More Reasons Not to Become Overweight and Obese
Being obese or overweight is, for the overwhelming majority of such individuals, a choice. There is plenty of ink spilled over how hard or easy the choice of body weight is to make, but it is nonetheless a choice. Want to weigh less? Then persist in eating fewer calories in the context of a sanely balanced diet. It really is as simple as that. The only way to fail is to fail to eat fewer calories. That this is eternally a challenge, and that obesity is increasingly prevalent in an environment of cheap calories, tells us more about human nature than it does about our biology.
The present consensus on the effects of e...
Source: Fight Aging! - October 11, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Why Do We Forgive?
This study, the first to elucidate the cumulative effects of severe stress and forgiveness on mental health, led authors to suggest development of a more forgiving coping strategy may be beneficial in reducing stress-caused disorders and conditions.
We Choose to Forgive
Considered a forgiveness trailblazer by Time Magazine and other media, Robert D. Enright, professor of psychology at the University of Wisconsin, Madison and president of the International Forgiveness Institute at UWMadison, is the author of Forgiveness Is a Choice: A Step-by-Step Process for Resolving Anger and Restoring Hope. In this self-help book, Enrig...
Source: World of Psychology - October 6, 2018 Category: Psychiatry & Psychology Authors: Suzanne Kane Tags: Ethics & Morality Family Friends Inspiration & Hope Source Type: blogs
Quite Simply: UNACCEPTABLE
Last week, my mom stunned me with bad news: A young woman named Tiffany Costa died. She was diagnosed with breast cancer in 2002 and died two weeks ago from stage II breast cancer at just 29 years old. She was metastatic for many years.
Tiffany’s extended family members are dear friends of my mom. I came to “meet” Tiffany because of an email my mom forwarded to me. She was being treated with Doxil. There was (and it would appear there still IS) a shortage of Doxil and she was trying to raise money to have the drugs brought into this country from Europe. The cost was exorbitant. I remember reading the email and I reca...
Source: Disruptive Women in Health Care - September 25, 2018 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Uncategorized Source Type: blogs
The Best Natural Sleep Aides
Melatonin should be the first nutritional supplement choice for restoring sleep patterns.
Melatonin is not a sleeping pill, as it does not share the characteristics of prescription sleeping pills: It does not adversely modify sleep patterns, it does not become habit-forming, and there is no withdrawal process when stopped. It simply “resets” your circadian clock to make your brain and body receptive to sleep. Numerous other benefits have been identified, including 70 percent reduction in tension headaches, 50 percent reduction in migraine headaches, reduction in chronic pain, and reduction in symptoms of irritable bowe...
Source: Wheat Belly Blog - September 20, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates 5-Hydroxytrptophan Dr. Davis health melatonin Natural Sleep Aides tryptophan undoctored wheat belly Source Type: blogs
Better Sleep . . . With Benefits
There are a handful of strategies that can augment or improve sleep quality while remaining consistent with the Wheat Belly lifestyle. Many people who banish all wheat and grains from their diet experience improvement in sleep duration and quality, further enhanced by our efforts to cultivate bowel flora. (Bowel flora metabolites have a major influence on sleep and dreams.) But, given life stress, transitional changes as you get further into this lifestyle, bad habits, and other factors sometimes make additional efforts necessary. But getting sufficient quality sleep can take you further down the path of health.
Melatonin ...
Source: Wheat Belly Blog - September 20, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates 5-Hydroxytrptophan Dr. Davis health melatonin Natural Sleep Aides oxytocin reuteri tryptophan undoctored wheat belly yogurt Source Type: blogs
FDA Launches New Campaign to Warn Kids about the Dangers of E-Cigarettes
The FDA launched a new, comprehensive campaign to warn kids about the dangers of e-cigarette use as part of the agency’s Youth Tobacco Prevention Plan.
“The Real Cost” Youth E-Cigarette Prevention Campaign will target nearly 10.7 million at-risk youth through digital platforms, social media, and in-school ads nationwide. With its tagline, “Know the Real Cost of Vaping,” the campaign aims to educate youth that using e-cigarettes, just like cigarettes, puts them at risk for addiction and other health consequences. The messages highlight that nicotine can rewire the brain to crave more nicotine, particularly because...
Source: BHIC - September 19, 2018 Category: Databases & Libraries Authors: Michelle Burda Tags: Children and Teens General Source Type: blogs
Writing as an antidote to loneliness
It may not seem possible to be able to write your way to better health. But as a doctor, a public health practitioner, and a poet myself, I know what the scientific data have to say about this: when people write about what’s in their hearts and minds, they feel better and get healthier. And it isn’t just that they’re getting their troubles off their chests.
Writing provides a rewarding means of exploring and expressing feelings. It allows you to make sense of yourself and the world you are experiencing. Having a deeper understanding of how you think and feel — that self-knowledge — provides you with a stronger co...
Source: Harvard Health Blog - September 14, 2018 Category: Consumer Health News Authors: Jeremy Nobel, MD, MPH Tags: Behavioral Health Mental Health Stress Source Type: blogs
Fight Aging! Newsletter, September 10th 2018
In conclusion, HSC ageing is characterised by reduced self-renewal, myeloid and platelet HSC skewing, and expanded clonal haematopoiesis that is considered a preleukaemic state. The underlying molecular mechanisms seem to be related to increased oxidative stress due to ROS accumulation and DNA damage, which are influenced by both cell- and cell non-autonomous mechanisms such as prolonged exposure to infections, inflammageing, immunosenescence, and age-related changes in the HSC niche. Thus, HSC ageing seems to be multifactorial and we are only beginning to connect all the dots.
The Price of Progress or the Waste...
Source: Fight Aging! - September 9, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
MRI Uncovers Missing Contact Lens Found 28 Years Later in Patient ’s Upper Eyelid
In Scotland, a contact lens that had gone missing for nearlythree decades was finally located when the owner of the lens underwent a MRI for upper eyelid swelling and ptosis.The MRI had indicated a cyst with proteinaceous content. When surgeons made an excision of the cyst, a rigid gas permeable (RGO) lens was discovered, deep in the upper eyelid soft tissue.“The features on the MRI were in keeping with a cyst with proteinaceous content. There were no radiological features of a foreign body seen within the cyst,” wrotethe patient ’s ophthalmologists in a report published in BMJ Case Reports.The disappearance of the...
Source: radRounds - August 30, 2018 Category: Radiology Authors: Julie Morse Source Type: blogs
Have You Run Out of Spoons? It ’ s Time to Replenish Your Energy Reserves
A few days ago, a friend indicated on her Facebook page that she had “run out of spoons” and asked for support and energy to be sent her way. I had heard the term but didn’t know what it meant, so I turned to Google and typed in those words and what came up was the explanation that came from a conversation between two friends, one of whom had Lupus.
Christine Miserandino was sitting at a table with her college roommate who asked her what it was like to have a disease that for many people would be considered invisible since overt symptoms may be elusive to the casual observer.
Christine pondered for an ever ...
Source: World of Psychology - August 15, 2018 Category: Psychiatry & Psychology Authors: Edie Weinstein, MSW, LSW Tags: Caregivers Inspiration & Hope Motivation and Inspiration Policy and Advocacy Stigma alone time caregiving Disability Disability Advocacy energy Rejuvenation Source Type: blogs
Fight Aging! Newsletter, August 13th 2018
We report that the disruption of excitation-contraction coupling contributes to impaired force generation in the mouse model of Sod1 deficiency. Briefly, we found a significant reduction in sarcoplasmic reticulum Ca2+ ATPase (SERCA) activity as well as reduced expression of proteins involved in calcium release and force generation. Another potential factor involved in EC uncoupling in Sod1-/- mice is oxidative damage to proteins involved in the contractile response.
In summary, this study provides strong support for the coupling between increased oxidative stress and disruption of cellular excitation contraction mac...
Source: Fight Aging! - August 12, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Call suicide by what it is: the cause of death
As is often the case when flying I was rewarded for offering a greeting to my row mate on the plane with a bit of insight and knowledge I’d have missed had I not simply reached out a hand and said, “Hi, I’m Darrell.” My momentary companion (we each moved to more spacious seats) had been a schoolmate of the recently deceased Kate Spade. He confirmed her years-long struggle with a depression that defied logic and was thus a depression that was as pathological as diabetes or heart disease or cancer. Opening my Sunday papers brings stories from the friends of Anthony Bourdain, also deceased, and his decades-long strugg...
Source: Kevin, M.D. - Medical Weblog - June 17, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/darrell-white" rel="tag" > Darrell White, MD < /a > Tags: Conditions Psychiatry Source Type: blogs
The Unknown Part of Anthony Bourdain
“Last time I saw all this, I think it’s fair to say, I was at a turning point in my life,” Anthony Bourdain says before embarking into the Borneo jungle. He was not afraid to discuss his long battle with substance use, an issue that millions of Americans struggle with.
In fact, recent data shows that annual deaths from opioid misuse have surpassed deaths by car accidents, guns, or breast cancer, highlighting an astoundingly dramatic increase in nationwide substance use disorders. 1, 2
“I have been hardened by the last 10 years. I don’t know what that says about me… but, there it is.” A crooked and nostalg...
Source: World of Psychology - June 9, 2018 Category: Psychiatry & Psychology Authors: Amanda Marie Cardinale Tags: Celebrities Depression General Stigma Suicide anthony bourdain bourdain suicide suicide of anthony bourdain Source Type: blogs
Dying from Dementia, Suffering Often Unnecessary
This discussion and research on Dying with Dementia and the unnecessary care that often accompanies the late stages of dementia is worth discussing and considering.ByAlzheimer's Reading RoomThis topic is often overlooked and avoided until it is too late.I believe these issues should be considered, and when possible,discussed in support groups. This information is worth sharing and discussing with family members.Learn More -Coping with Alzheimer'sSince individuals with advanceddementia cannot report their symptoms, these symptoms often are untreated, leaving them vulnerable to pain, difficulty breathing and various other co...
Source: Alzheimer's Reading Room, The - June 6, 2018 Category: Neurology Tags: Alzheimer's Dementia assisted living and memory care facility care homes for elderly with dementia care of dementia patients care of dementia patients at home dementia care elderly dementia care Source Type: blogs
