Why poor diets are contributing to a surge in colorectal cancer cases among young people
An alarming trend has emerged in my medical practice in recent years: I’m seeing more and more young adults with colorectal cancer. When I began practicing as a family physician 21 years ago, I never saw patients in their 40s and 50s with the disease, much less ones in their 30s. Now, I diagnose two Read more… Why poor diets are contributing to a surge in colorectal cancer cases among young people originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 26, 2023 Category: General Medicine Authors: Tags: Conditions Gastroenterology Oncology/Hematology Source Type: blogs

Changing the pediatric care landscape: Integrating behavioral and mental health care
One in five children and adolescents will receive a behavioral or mental health diagnosis by 18. That is more than the number of women diagnosed with breast cancer (1 in 8). According to the American Academy of Child and Adolescent Psychiatry, 50 percent of pediatric office visits involve behavioral, social-emotional, or developmental concerns. Seventy percent Read more… Changing the pediatric care landscape: Integrating behavioral and mental health care originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 22, 2023 Category: General Medicine Authors: Tags: Conditions Pediatrics Psychiatry Source Type: blogs

Idaho Public Television and State Health Officials Lie to the Public by Telling them Smoking is Not More Harmful than Vaping
In a public education campaign entitled " Do You Know Vape? " Idaho Public Television in collaboration with the state health districts isinforming the public that: " Vaping isnot safer than cigarette smoking. "The campaign is also making several other alarming claims, including that:vaping causes brain, bone, and lung injury to young people;third-hand aerosol from vaping (i.e., particles that stick to surfaces) can cause "asthma,respiratory illness, increased risk of disease, headaches andincreased risk of cancer" ; and vaping exposes users tometals in the lungs that can cause lung cancer.The Rest of the StoryRather t...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - March 21, 2023 Category: Addiction Source Type: blogs

Fight Aging! Newsletter, January 16th 2023
Conclusions Implanted Hair Follicle Cells Produce Remodeling of Scar Tissue Assessment of Somatic Mosaicism as a Biomarker of Aging The Gut Microbiome of Centenarians https://www.fightaging.org/archives/2023/01/the-gut-microbiome-of-centenarians/ The state of the gut microbiome is arguably as influential on health as exercise. Various microbial species present in the gut produce beneficial metabolites, such as butyrate, or harmful metabolites, such as isoamylamine, or can provoke chronic inflammation in a variety of ways. An individual can have a better or worse microbiome, assessing these and other...
Source: Fight Aging! - January 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, December 5th 2022
In conclusion, the PAAIs examined (i.e. mTOR loss of function, Ghrhr loss of function, intermittent fasting-based version of dietary restriction) often influenced age-sensitive traits in a direct way and not by slowing age-dependent change. Previous studies often failed to include young animals subjected to PAAI to account for age-independent PAAI effects. However, any study not accounting for such age-independent intervention effects will be prone to overestimate the extent to which an intervention delays the effects of aging on the phenotypes studied. This can result in a considerable bias of our view on how modifiable a...
Source: Fight Aging! - December 4, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, November 21st 2022
In this study researchers added new insight, showing that high-intensity aerobic exercise, which derives its energy from sugar, can reduce the risk of metastatic cancer by as much as 72%. If so far the general message to the public has been 'be active, be healthy', now researchers can explain how aerobic activity can maximize the prevention of the most aggressive and metastatic types of cancer. The study combined an animal model in which mice were trained under a strict exercise regimen, with data from healthy human volunteers examined before and after running. The human data, obtained from an epidemiological study ...
Source: Fight Aging! - November 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, November 14th 2022
In this study, we show that TXNIP is vital for the cell fate choice when cells are challenged by various stress signals. Furthermore, prolonged IGF1 treatment leads to the establishment of a premature senescence phenotype characterized by a unique senescence network signature. Combined IGF1/TXNIP-induced premature senescence can be associated with a typical secretory inflammatory phenotype that is mediated by STAT3/IL-1A signaling. Finally, these mechanistic insights might help with the understanding of basic aspects of IGF1-related pathologies in the clinical setting. Investigating the Ability of Type 2 Diabetes...
Source: Fight Aging! - November 13, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, November 7th 2022
In conclusion, the national prevalence of dementia and MCI in 2016 found in this cross-sectional study was similar to that of other US-based studies. Clearing Microglia Reverses Age-Related Disruption of Sleeping Patterns in Mice https://www.fightaging.org/archives/2022/11/clearing-microglia-reverses-age-related-disruption-of-sleeping-patterns-in-mice/ Microglia are innate immune cells of the central nervous system. They are analogous to macrophages in the rest of the body, but undertake additional duties relating to the function of neurons and in brain tissue. Microglia become overly active and inflamm...
Source: Fight Aging! - November 6, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

An old interview with one of this year ’ s Nobel Chemists – Carolyn Bertozzi
This was an interview for my Personal Reactions column on the old ChemWeb site from 1999 featuring Carolyn Bertozzi, who this week was announced as one of three recipients of the 2022 Nobel Prize in Chemistry. Biography: Professor Carolyn Ruth Bertozzi, born 10th October 1966. Boston Massachusetts. Position: Associate Professor of Chemistry, University of California at Berkeley How did you get your current job? The usual way. I applied for faculty positions in 1995 in response to advertisements in C&E News What do you think clinched the deal? Good fortune and a strong publication record from my graduate and postdoctora...
Source: David Bradley Sciencebase - Songs, Snaps, Science - October 7, 2022 Category: Science Authors: David Bradley Tags: Chemistry Source Type: blogs

TLC Todd-versations: Todd Linsky in Conversation with Dr. Alan Greene
Todd Linsky, a food and organic industry veteran, hosts the podcast Todd-versations. He interviews guests from around the globe — influencers, leaders, and innovators in their respective fields. In this episode, Todd and Dr. Greene discuss the pediatric roots of longevity, the importance of nutrition in health, Dr. Greene’s reasons for creating DrGreene.com, his next projects, and a whole host of side topics. Transcript of Todd-versation Podcast with Todd Linsky and Dr. Greene 0:00 this conversation is brought to you in part by Calavo Growers the family of fresh! 0:19 hey there everybody good ...
Source: Conversations with Dr Greene - October 6, 2022 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Source Type: blogs

Commentators and Journalists Weigh In On Digital Health And Related Privacy, Safety, Social Media And Security Matters. Lots Of Interesting Perspectives - September 27, 2022.
Conclusions:This study revealed strong and consistent patterns of association between digital health literacy and the use of a web-based PHR. The results indicate potential actions for promoting PHR uptake, including improving digital technology and skill experiences that may improve digital health literacy and willingness to engage in web-based PHR. Uptake may also be improved through more responsive digital services, strengthened health care, and better social support. A holistic approach, including targeted solutions, is needed to ensure that web-based PHR can realize its full potential to help reduce health inequities....
Source: Australian Health Information Technology - September 27, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Weekly Overseas Health IT Links –24th September, 2022.
This article makes the case and explains what will be required to make it happen.We hear a lot about “digital health” these days. As data about our health piles up — thanks to sources like electronic health records, personal fitness apps and gadgets, and home genome test kits — weshould understand a lot more than we used to about what ’s wrong with our health and what to do about it. But having a lot of data is not enough. We have to be aware of what we have, understand what it means, and act on that understanding. While the challenges are in some ways more acute in the United States because of its fragmented sys...
Source: Australian Health Information Technology - September 24, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Fight Aging! Newsletter, August 29th 2022
This study demonstrates that adoptive astrocytic Mt transfer enhances neuronal Mn-SOD-mediated anti-oxidative defense and neuroplasticity in the brain, which potentiate functional recovery following ICH. First Generation Stem Cell Therapies Remain Comparatively Poorly Understood https://www.fightaging.org/archives/2022/08/first-generation-stem-cell-therapies-remain-comparatively-poorly-understood/ We are something like thirty years into the increasingly widespread use of first generation stem cell therapies. Cells are derived from a variety of sources, processed, and transplanted into patients. Near all...
Source: Fight Aging! - August 28, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
August 25, 2022 Edition-----The big story this week has been the multiple PM story in Australia with ScoMo. What an amazing saga!In the UK there seems to be an impending collapse of the economy coming unless some-one takes some really smart steps real soon now.Relatively the US has seemed pretty calm this week – just waiting for an impending recession – along with China and Europe.Fair to say things globally are pretty messy!-----Major Issues.-----https://www.afr.com/markets/equity-markets/every-investing-trend-misfires-as-stock-bears-are-crushed-20220814-p5b9o2Every investing trend misfires as stock bears are crushedD...
Source: Australian Health Information Technology - August 25, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Help me solve this puzzle
The IASP definition of pain is: An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage. Six key notes and etymology: Pain is always a personal experience that is influenced to varying degrees by biological, psychological, and social factors.Pain and nociception are different phenomena. Pain cannot be inferred solely from activity in sensory neurons.Through their life experiences, individuals learn the concept of pain.A person’s report of an experience as pain should be respected.Although pain usually serves an adaptive role, it may ...
Source: HealthSkills Weblog - June 12, 2022 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Clinical reasoning Pain conditions Research healthcare Source Type: blogs