Fight Aging! Newsletter, January 16th 2023

Conclusions Implanted Hair Follicle Cells Produce Remodeling of Scar Tissue Assessment of Somatic Mosaicism as a Biomarker of Aging The Gut Microbiome of Centenarians https://www.fightaging.org/archives/2023/01/the-gut-microbiome-of-centenarians/ The state of the gut microbiome is arguably as influential on health as exercise. Various microbial species present in the gut produce beneficial metabolites, such as butyrate, or harmful metabolites, such as isoamylamine, or can provoke chronic inflammation in a variety of ways. An individual can have a better or worse microbiome, assessing these and other functional contributions to health. With age, the balance of populations shifts towards fewer benefits and greater harm, unfortunately. Since the composition of the microbiome can be assessed accurately and cheaply via 16S rRNA sequencing, understanding of the gut microbiome is advancing rapidly. There is no one optimal gut microbiome, but some species are more helpful than others. Looking at human populations, researchers are beginning to see patterns emerge from the study of the gut microbiome in healthier and more long-lived people. Today's open access paper is an example of this sort of work, in which the microbiomes of centenarians are assessed and compared with the broader population. This is all interesting, but a short-cut to improving the aged gut microbiome does exist, in advance on understanding all of the desired component species,...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs