Umbilical Hernias: Systemic Racism, Dogma, And Pediatric Surgery
by Stephanie Preston, MD In the health professions, we have all been taught that some of the most common, chronic, and debilitating diseases in the United States – hypertension, diabetes, heart disease, and most cancers – disproportionately affect Black Americans. As resident surgeons, dogma holds that umbilical hernias are more prevalent in Black children, but without any discussion about underlying drivers. There is no evidence to support that this disparity is related to biologic or genetic differences. However, a recently published study continues to state that umbilical hernias are 8-9x more prevalent among Bla...
Source: blog.bioethics.net - April 13, 2021 Category: Medical Ethics Authors: Blog Editor Tags: Children/Adolescents Ethics Featured Posts Health Care Health Disparities Pediatrics Source Type: blogs

Fight Aging! Newsletter, April 5th 2021
In this study, the research team designed a way to identify small molecules that improve the function of ABCA1 in the body while avoiding unwanted effects to the liver. The researchers honed in on a specific small molecule, CL2-57, due to its ability to stimulate ABCA1 activity with positive effects on liver and plasma triglycerides. The use of this compound showed improved glucose tolerance and insulin sensitivity, as well as reduced weight gain, among other beneficial effects. Age-Related Upregulation of Autophagy as a Possible Contribution to Bat Longevity https://www.fightaging.org/archives/2021/04/age-rel...
Source: Fight Aging! - April 4, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

What ’s your approach to health? Check your medicine cabinet
Do all kids spy? Just me? When I was a child, I spent hours snooping in my parents’ nightstands, Granny’s pocketbook, my older brothers’ dresser drawers. I’m not sure what I was looking for, exactly, other than validation of my suspicion that the teenagers and adults in my life were keeping secrets from me. And no opportunity for sleuthing seemed richer than the twin mirrored medicine cabinets hanging from my parents’ bathroom wall. My mother’s was kind of boring, its glass shelves lined with bottles of aspirin and antacids, plus a dusty jar of jewel-toned bath oil beads. My father’s was a treasure trove ...
Source: Harvard Health Blog - February 16, 2021 Category: Consumer Health News Authors: Suzanne Koven, MD, MFA Tags: Health Healthy Aging Healthy Eating Managing your health care Source Type: blogs

New dietary guidelines: Any changes for infants, children, and teens?
The United States Department of Agriculture (USDA) has published new dietary guidelines to help Americans get and stay healthier across all parts of the lifespan. Babies and toddlers are included for the first time, because the recommendations cover our full lifespan. The guidelines are called “Make Every Bite Count.” If we want to get and stay healthy, we shouldn’t be eating foods that are basically empty calories — or worse, foods that actually do us harm. Because foods can do us harm. Eating an unhealthy diet can lead to obesity, with the cardiovascular disease, diabetes, high blood pressure, and everything else...
Source: Harvard Health Blog - January 26, 2021 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Adolescent health Children's Health Healthy Eating Parenting Source Type: blogs

Fight Aging! Newsletter, January 11th 2021
This study demonstrates the potential of a natural (o-Vanillin) and a synthetic (RG-7112) senolytic compounds to remove senescent IVD cells, decrease SASP factors release, reduce the inflammatory environment and enhance the IVD matrix production. Removal of senescent cells, using senolytics drugs, could lead to improved therapeutic interventions and ultimately decrease pain and a provide a better quality of life of patients living with intervertebral disc degeneration and low back pain. From Ying Ann Chiao of Oklahoma Medical Research Foundation: Mitochondrial dysfunction plays a central role in aging and cardiovasc...
Source: Fight Aging! - January 10, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

My Benjamin Hartman Story
“I need intravenous Beefsteak,” I texted my forever-Beefsteak date Ben Hartman, who others called Benjie or Bean or sometimes Boozey, and who I called Kryptonite or sometimes Sushi Ben. “See you there at 6:30,” he texted back. Since meeting in 2014, we each accommodated the other when it came to Beefsteak — a fast-casual restaurant near George Washington University that served paleo-friendly fare before paleo was cool and offered outdoor seating long before covid-19. My gcalendar archive shows that we made seven Beefsteak dates in advance, though that’s a fraction of our total as most stemmed fro m mi...
Source: cancerslayerblog - December 5, 2020 Category: Cancer & Oncology Tags: death life lessons Source Type: blogs

Fight Aging! Newsletter, November 23rd 2020
In conclusion, the study indicates that HBOT may induce significant senolytic effects that include significantly increasing telomere length and clearance of senescent cells in the aging populations. Data on the Prevalence of Liver Fibrosis in Middle Age https://www.fightaging.org/archives/2020/11/data-on-the-prevalence-of-liver-fibrosis-in-middle-age/ Fibrosis is a consequence of age-related disarray in tissue maintenance processes, leading to the deposition of scar-like collagen that disrupts tissue structure and function. It is an ultimately fatal issue for which there are only poor treatment options ...
Source: Fight Aging! - November 22, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Health Care 101 Continued: The allocation problem
We often hear sentiments to the effect that human life is infinitely precious, that you can ' t put a price on human life. While most people probably think this instinctively, it is conservatives, and particularly religious conservatives, who are most likely to try to apply the concept in reality. Do you remember the ravings about " death panels " when the Affordable Care Act passed? Of course there ' s nothing in the ACA that could conceivably be construed that way, but the scary meme was imported from arguments about single payer or, as in the UK, socialized medicine schemes.To put this in the simplest and starkest terms...
Source: Stayin' Alive - October 23, 2020 Category: American Health Source Type: blogs

Caregiving for Schizophrenia
A third of all people will be a caregiver at some point in their lives. Caregiving for people with schizophrenia presents challenges that many people are ill-prepared for. Host Rachel Star breaks down the principles of caregiving and creative ways to navigate schizophrenia. Dr. Sarah Kopelovich joins to share schizophrenia caregiver specific training. About our Guest Sarah Kopelovich, PhD is a forensically-trained licensed clinical psychologist in the Department of Psychiatry and Behavioral Sciences at the University of Washington School of Medicine. Dr. Kopelovich is an Assistant Professor in the department and holds the...
Source: World of Psychology - October 21, 2020 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Brain and Behavior Caregivers Family Inside Schizophrenia Mental Health and Wellness Psychology Adult Caregiver Caregiver stress Family Caregivers life with schizophrenia Living With Schizophrenia Mental Illness Psychotherapy Sel Source Type: blogs

Inside Schizophrenia: Caregiving for Schizophrenia
A third of all people will be a caregiver at some point in their lives. Caregiving for people with schizophrenia presents challenges that many people are ill-prepared for. Host Rachel Star breaks down the principles of caregiving and creative ways to navigate schizophrenia. Dr. Sarah Kopelovich joins to share schizophrenia caregiver specific training. About our Guest Sarah Kopelovich, PhD is a forensically-trained licensed clinical psychologist in the Department of Psychiatry and Behavioral Sciences at the University of Washington School of Medicine. Dr. Kopelovich is an Assistant Professor in the department and holds the...
Source: World of Psychology - October 21, 2020 Category: Psychiatry & Psychology Authors: Rachel Star Withers Tags: Brain and Behavior Caregivers Family Inside Schizophrenia Mental Health and Wellness Psychology Adult Caregiver Caregiver stress Family Caregivers life with schizophrenia Living With Schizophrenia Mental Illness Psychotherapy Sel Source Type: blogs

Fight Aging! Newsletter, October 12th 2020
We report that FMT from aged donors led to impaired spatial learning and memory in young adult recipients, whereas anxiety, explorative behaviour, and locomotor activity remained unaffected. This was paralleled by altered expression of proteins involved in synaptic plasticity and neurotransmission in the hippocampus. Also, a strong reduction of bacteria associated with short-chain fatty acids (SCFAs) production (Lachnospiraceae, Faecalibaculum, and Ruminococcaceae) and disorders of the CNS (Prevotellaceae and Ruminococcaceae) was observed. Finally, the detrimental effect of FMT from aged donors on the CNS was confir...
Source: Fight Aging! - October 11, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, September 21st 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 20, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Evidence for Familial Longevity to be Largely Cultural Rather than Genetic
It is certainly possible that a small number of people have mutations or genetic variants that confer notable longevity. The small lineage exhibiting a PAI-1 loss of function mutation springs to mind as an example of this sort of thing. But for the overwhelming majority of long-lived lineages, the evidence on genetic contributions to longevity tends to support the hypothesis that familial longevity arises much more from lifestyle and environment than from inherited genetics. The data from very large genetic databases points to genetic variants contributing little to variation in human life span. The data on exercise, diet,...
Source: Fight Aging! - September 14, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs