Hyperpolarized < sup > 15 < /sup > N caffeine, a potential probe of liver function and perfusion
CONCLUSION: These results establish the feasibility of hyperpolarization of hyperpolarized 15 N-caffeine, but further work is necessary to establish the role of this new agent to probe liver metabolism and perfusion.PMID:38469685 | DOI:10.1002/mrm.30070 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - March 12, 2024 Category: Radiology Authors: Cornelius von Morze Ashley Shaw Tyler Blazey Source Type: research
The neuroprotective effect of exogen melatonin upon fetal hippocampus damage caused by high-dose caffeine administration in pregnant rats
CONCLUSION: It is concluded that high-dose CAF administration causes a delay in neurogenesis of the fetal hippocampus, and exogenous MEL is able to mitigate its deleterious effects.PMID:38469915 | DOI:10.1002/jdn.10323 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - March 12, 2024 Category: Neuroscience Authors: Ya ğmur Köse Cans ın Şirin Ali Çağlar Turgut Canberk Tomruk Yi ğit Uyanıkgil Mehmet Turgut Source Type: research
Hyperpolarized < sup > 15 < /sup > N caffeine, a potential probe of liver function and perfusion
CONCLUSION: These results establish the feasibility of hyperpolarization of hyperpolarized 15 N-caffeine, but further work is necessary to establish the role of this new agent to probe liver metabolism and perfusion.PMID:38469685 | DOI:10.1002/mrm.30070 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - March 12, 2024 Category: Radiology Authors: Cornelius von Morze Ashley Shaw Tyler Blazey Source Type: research
The neuroprotective effect of exogen melatonin upon fetal hippocampus damage caused by high-dose caffeine administration in pregnant rats
CONCLUSION: It is concluded that high-dose CAF administration causes a delay in neurogenesis of the fetal hippocampus, and exogenous MEL is able to mitigate its deleterious effects.PMID:38469915 | DOI:10.1002/jdn.10323 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - March 12, 2024 Category: Neuroscience Authors: Ya ğmur Köse Cans ın Şirin Ali Çağlar Turgut Canberk Tomruk Yi ğit Uyanıkgil Mehmet Turgut Source Type: research
Hyperpolarized < sup > 15 < /sup > N caffeine, a potential probe of liver function and perfusion
CONCLUSION: These results establish the feasibility of hyperpolarization of hyperpolarized 15 N-caffeine, but further work is necessary to establish the role of this new agent to probe liver metabolism and perfusion.PMID:38469685 | DOI:10.1002/mrm.30070 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - March 12, 2024 Category: Radiology Authors: Cornelius von Morze Ashley Shaw Tyler Blazey Source Type: research
The neuroprotective effect of exogen melatonin upon fetal hippocampus damage caused by high-dose caffeine administration in pregnant rats
CONCLUSION: It is concluded that high-dose CAF administration causes a delay in neurogenesis of the fetal hippocampus, and exogenous MEL is able to mitigate its deleterious effects.PMID:38469915 | DOI:10.1002/jdn.10323 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - March 12, 2024 Category: Neuroscience Authors: Ya ğmur Köse Cans ın Şirin Ali Çağlar Turgut Canberk Tomruk Yi ğit Uyanıkgil Mehmet Turgut Source Type: research
Hyperpolarized < sup > 15 < /sup > N caffeine, a potential probe of liver function and perfusion
CONCLUSION: These results establish the feasibility of hyperpolarization of hyperpolarized 15 N-caffeine, but further work is necessary to establish the role of this new agent to probe liver metabolism and perfusion.PMID:38469685 | DOI:10.1002/mrm.30070 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - March 12, 2024 Category: Radiology Authors: Cornelius von Morze Ashley Shaw Tyler Blazey Source Type: research
Hyperpolarized < sup > 15 < /sup > N caffeine, a potential probe of liver function and perfusion
CONCLUSION: These results establish the feasibility of hyperpolarization of hyperpolarized 15 N-caffeine, but further work is necessary to establish the role of this new agent to probe liver metabolism and perfusion.PMID:38469685 | DOI:10.1002/mrm.30070 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - March 12, 2024 Category: Radiology Authors: Cornelius von Morze Ashley Shaw Tyler Blazey Source Type: research
Hyperpolarized < sup > 15 < /sup > N caffeine, a potential probe of liver function and perfusion
CONCLUSION: These results establish the feasibility of hyperpolarization of hyperpolarized 15 N-caffeine, but further work is necessary to establish the role of this new agent to probe liver metabolism and perfusion.PMID:38469685 | DOI:10.1002/mrm.30070 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - March 12, 2024 Category: Radiology Authors: Cornelius von Morze Ashley Shaw Tyler Blazey Source Type: research
Monitoring of Caffeine Consumption Effect on Skin Blood Properties by Diffuse Reflectance Spectroscopy
In this study we investigate the use of diffuse reflectance spectroscopy (DRS) for monitoring of vascular changes in human skin induced by caffeine consumption. DRS spectra were recorded on volar sides of the forearms of eight healthy volunteers at time intervals of 0, 30, 60, 120, and 180 min after consumption of caffeine, while one subject served as a negative control. Analytical diffusion approximation solutions for diffuse reflectance from three-layer structures were used to assess skin composition (e.g. dermal blood volume fraction and oxygen saturation) by fitting these solutions to experimental data. The results dem...
Source: Physiological Research - March 11, 2024 Category: Physiology Authors: M Milanic R Hren J Stergar U Simoncic Source Type: research
Monitoring of Caffeine Consumption Effect on Skin Blood Properties by Diffuse Reflectance Spectroscopy
In this study we investigate the use of diffuse reflectance spectroscopy (DRS) for monitoring of vascular changes in human skin induced by caffeine consumption. DRS spectra were recorded on volar sides of the forearms of eight healthy volunteers at time intervals of 0, 30, 60, 120, and 180 min after consumption of caffeine, while one subject served as a negative control. Analytical diffusion approximation solutions for diffuse reflectance from three-layer structures were used to assess skin composition (e.g. dermal blood volume fraction and oxygen saturation) by fitting these solutions to experimental data. The results dem...
Source: Physiological Research - March 11, 2024 Category: Physiology Authors: M Milanic R Hren J Stergar U Simoncic Source Type: research
Monitoring of Caffeine Consumption Effect on Skin Blood Properties by Diffuse Reflectance Spectroscopy
In this study we investigate the use of diffuse reflectance spectroscopy (DRS) for monitoring of vascular changes in human skin induced by caffeine consumption. DRS spectra were recorded on volar sides of the forearms of eight healthy volunteers at time intervals of 0, 30, 60, 120, and 180 min after consumption of caffeine, while one subject served as a negative control. Analytical diffusion approximation solutions for diffuse reflectance from three-layer structures were used to assess skin composition (e.g. dermal blood volume fraction and oxygen saturation) by fitting these solutions to experimental data. The results dem...
Source: Physiological Research - March 11, 2024 Category: Physiology Authors: M Milanic R Hren J Stergar U Simoncic Source Type: research
Caffeine in Hepatocellular Carcinoma: Cellular Assays, Animal Experiments, and Epidemiological Investigation
(Source: Journal of Inflammation Research)
Source: Journal of Inflammation Research - March 11, 2024 Category: Allergy & Immunology Tags: Journal of Inflammation Research Source Type: research
Early versus late caffeine and/or non-steroidal anti-inflammatory drugs (NSAIDS) for prevention of intermittent hypoxia-induced neuroinflammation in the neonatal rat
Int J Dev Neurosci. 2024 Mar 8. doi: 10.1002/jdn.10321. Online ahead of print.ABSTRACTPreterm infants often experience frequent intermittent hypoxia (IH) episodes which are associated with neuroinflammation. We tested the hypotheses that early caffeine and/or non-steroidal inflammatory drugs (NSAIDs) confer superior therapeutic benefits for protection against IH-induced neuroinflammation than late treatment. Newborn rats were exposed to IH or hyperoxia (50% O2 ) from birth (P0) to P14. For early treatment, the pups were administered: 1) daily caffeine (Caff) citrate (Cafcit, 20 mg/kg IP loading on P0, followed by 5 mg/kg f...
Source: International Journal of Developmental Neuroscience - March 9, 2024 Category: Neuroscience Authors: Myra Batool Charles L Cai Jacob V Aranda Ivan Hand Kay D Beharry Source Type: research
Early versus late caffeine and/or non-steroidal anti-inflammatory drugs (NSAIDS) for prevention of intermittent hypoxia-induced neuroinflammation in the neonatal rat
Int J Dev Neurosci. 2024 Mar 8. doi: 10.1002/jdn.10321. Online ahead of print.ABSTRACTPreterm infants often experience frequent intermittent hypoxia (IH) episodes which are associated with neuroinflammation. We tested the hypotheses that early caffeine and/or non-steroidal inflammatory drugs (NSAIDs) confer superior therapeutic benefits for protection against IH-induced neuroinflammation than late treatment. Newborn rats were exposed to IH or hyperoxia (50% O2 ) from birth (P0) to P14. For early treatment, the pups were administered: 1) daily caffeine (Caff) citrate (Cafcit, 20 mg/kg IP loading on P0, followed by 5 mg/kg f...
Source: International Journal of Developmental Neuroscience - March 9, 2024 Category: Neuroscience Authors: Myra Batool Charles L Cai Jacob V Aranda Ivan Hand Kay D Beharry Source Type: research
