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Music, Science, PARP And The Meaning Of A New Drug For Metastatic Breast Cancer With BRCA Mutations
So far, data from the OlympiAD trial for Lynparza in breast cancer are not impressive in a " Wow " kind of way. But the potential application of this, and other PARP inhibitors, is huge. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 19, 2018 Category: Pharmaceuticals Authors: Elaine Schattner, Contributor Source Type: news

Immediate breast reconstruction after mastectomy does not delay start of chemotherapy or radiotherapy – but may increase risk of complications and readmission
Having immediate reconstruction following a mastectomy does not delay the start of a patient ’ s adjuvant breast cancer therapy but may increase the likelihood of complications requiring hospital readmission in the first six weeks after surgery, according to new research led by researchers at the University of Bristol and the Royal Liverpool University Hospital presented at the UK Interdisciplinary Breast Cancer Symposium (UKIBCS) in Manchester – hosted by leading charity Breast Cancer Now. (Source: University of Bristol news)
Source: University of Bristol news - January 19, 2018 Category: Universities & Medical Training Tags: Health, International; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Faculty of Health Sciences, Population Health Sciences; Press Release Source Type: news

Researchers find link between breast cancer and two gene mutations
(Springer) Individuals with Lynch syndrome, a genetic condition that has long been known to carry dramatically increased risk of colorectal cancer and uterine cancer, now also have an increased risk of breast cancer. This is the conclusion of a study in the journal Genetics in Medicine which is published by Springer Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: news

Factor that doubles the risk of death from breast cancer identified
(Karolinska Institutet) Researchers at Karolinska Institutet in Sweden have discovered that the risk of death from breast cancer is twice as high for patients with high heterogeneity of the oestrogen receptor within the same tumour as compared to patients with low heterogeneity. The study, published in The Journal of the National Cancer Institute, shows that the higher risk of death is independent of other known tumour markers and also holds true for Luminal A breast cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: news

MIT Portugal is developing a compression sleeve for breast cancer patients
(MIT Portugal Program) The project developed by the MIT Portugal Ph.D. Student at the University of Minho Carlos Gon ç alves, was considered the most innovative of the nine projects incubated during 10 weeks by Startup Nano, a pioneer incubation and acceleration program for nanotechnology innovation promoted by Startup Braga in a partnership with the International Iberian Nanotechnology Laboratory and the Centre for Nanotechnology and Smart Materials (CeNTI) both located in Braga. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: news

Obamacare Led to Rise in Breast Cancer Screening
(Source: Cancercompass News: Breast Cancer)
Source: Cancercompass News: Breast Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: news

The Pill Lowers Ovarian Cancer Risk, Even for Smokers
(Source: Cancercompass News: Breast Cancer)
Source: Cancercompass News: Breast Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: news

Testing all women over 30 could prevent 80k cancer cases  
Currently only women known to have family with the dangerous genes are offered DNA blood tests. But experts at Barts Cancer Institute in London calculated 64,500 could be spared breast cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - January 18, 2018 Category: Consumer Health News Source Type: news

New HHS civil rights division charged with protecting health-care workers with moral objections
Acting Health and Human Services secretary Eric Hargan on Thursday announced the creation of a new conscience and religious freedom division aimed at protecting doctors, nurses and other health-care workers who decline to participate in care that goes against their moral or religious convictions. Speaking at an event featuring Republican lawmakers and religious leaders, Hargan noted that […]Related:FDA to release more clinical trial information for newly approved drugsCDC postpones session on ‘preparing for the unthinkable’: a nuclear blastFirst treatment approved for breast cancer with BRCA ge...
Source: Washington Post: To Your Health - January 18, 2018 Category: Consumer Health News Source Type: news

Obamacare Led to Rise in Breast Cancer Screening
After the rule went into effect, the study found, the number of women in Medicare Advantage plans who got mammography screening rose by 5.5 percentage points: from just under 60 percent in the two years before the rule, to 65.4 percent in the two years after. (Source: WebMD Health)
Source: WebMD Health - January 18, 2018 Category: Consumer Health News Source Type: news

Obamacare Led to Rise in Breast Cancer Screening
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 18, 2018 Category: Cancer & Oncology Tags: Family Medicine, Oncology, Radiology, News, Source Type: news

Radioactive Seed Localization or Wire-guided Localization of Nonpalpable Invasive and In Situ Breast Cancer: A Randomized, Multicenter, Open-label Trial
This research article has led to a Practice Changing Update in DynaMed Plus. It concludes that radioactive seed localization may have similar positive margin but higher successful placement rates compared to wire localization in women having breast-conserving surgery for nonpalpable invasive breast cancer or ductal carcinoma in situ (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 18, 2018 Category: Consumer Health News Source Type: news

Obamacare Led to Rise in Breast Cancer Screening
THURSDAY, Jan. 18, 2018 -- More American women started getting recommended mammography screening after an " Obamacare " rule made the tests free, a new study finds. The rule meant that Medicare and most private insurers could no longer require women... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - January 18, 2018 Category: General Medicine Source Type: news

Obamacare Led to Rise in Breast Cancer Screening
Title: Obamacare Led to Rise in Breast Cancer ScreeningCategory: Health NewsCreated: 1/18/2018 12:00:00 AMLast Editorial Review: 1/18/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - January 18, 2018 Category: Cancer & Oncology Source Type: news

What's the best way to follow up breast cancer survivors?
How should women with breast cancer be tracked after lumpectomy or mastectomy?...Read more on AuntMinnie.comRelated Reading: Women don't know about breast cancer treatment options At-risk women not receiving breast MRI scans Most women prefer annual breast cancer screening Screening breast MRI alone OK for high-risk women Mammography guidelines don't change screening intervals (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 18, 2018 Category: Radiology Source Type: news

Proteomic Profiling of Breast Cancer Metabolism Proteomic Profiling of Breast Cancer Metabolism
What is the relationship between metabolism-associated proteins and survival in patients with breast cancer?Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 18, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Can mice really mirror humans when it comes to cancer?
(Michigan State University) A new Michigan State University study is helping to answer a pressing question among scientists of just how close mice are to people when it comes to researching cancer. The findings reveal how mice can actually mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 18, 2018 Category: Cancer & Oncology Source Type: news

Two new breast cancer genes emerge from lynch syndrome gene study
(Columbia University Medical Center) Columbia University researchers have identified two new breast cancer genes that also cause Lynch syndrome. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 18, 2018 Category: Cancer & Oncology Source Type: news

Testing could prevent 80,000 cancer cases  
Currently only women known to have family with the dangerous genes are offered DNA blood tests. But experts at Barts Cancer Institute in London calculated 64,500 could be spared breast cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - January 18, 2018 Category: Consumer Health News Source Type: news

More women get breast screening after ACA bans copays
More women participated in mammography screening when they no longer had to...Read more on AuntMinnie.comRelated Reading: What are the risks of risk-based breast cancer screening? Study: ACA led to more early-stage cancer diagnoses Women overestimate breast cancer risk, prefer biopsy Study: ACA leads to earlier breast cancer diagnoses Study links ACA with earlier cancer diagnosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 17, 2018 Category: Radiology Source Type: news

Late Recurrence in ER- Positive Breast Cancer: Banking on Biomarkers Late Recurrence in ER- Positive Breast Cancer: Banking on Biomarkers
Evaluation of biomarkers after 5 years of standard therapy for hormone-positive breast cancer may help determine those at risk for recurrence and those who may need further endocrine therapy.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 17, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Dr Reddy's recalls over 1,000 vials of cancer drug from US
Health regulators raised a red flag over a defect in the sealing of Docetaxel injection vials- a drug used for treating breast cancer. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 17, 2018 Category: Pharmaceuticals Source Type: news

The Biomarker Disruptor
Would you rather get a biopsy or a blood test to check for prostate cancer? Quanterix chairman/CEO Kevin Hrusovsky said with the help of his company's latest product, the SR-X Ultra-Sensitive Biomarker Detection System, a simple blood test could replace, or complement, invasive diagnostic procedures. Using digital technology, the SR-X can detect cancer, neurological disorders, inflammatory and infectious diseases, and heart events months or even years earlier, and less invasively, than existing technology.   Using Quanterix's single molecule array (Simoa) science, which is similar to a digital enzyme-linked immunosorb...
Source: MDDI - January 16, 2018 Category: Medical Devices Authors: Heather R. Johnson Tags: IVD Source Type: news

New Analytical Tool May Determine How DCIS Invasion Occurs
A new analytical tool called topographic single-cell sequencing can reveal a direct genomic lineage between in situ and invasive tumor subpopulations, which may help decipher how and why some DCIS become invasive. (Source: CancerNetwork)
Source: CancerNetwork - January 16, 2018 Category: Cancer & Oncology Authors: John Schieszer Tags: Breast Cancer News Source Type: news

FDA to release more clinical trial information for newly approved drugs
The Food and Drug Administration is taking steps to make it easier for doctors, patients and researchers to get access to clinical trial data amassed during the process of approving new drugs, Commissioner Scott Gottlieb said Tuesday. Gottlieb announced the actions just before a speech on FDA transparency at a Washington forum. The meeting, attended by […]Related:CDC postpones session on ‘preparing for the unthinkable’: a nuclear blastFirst treatment approved for breast cancer with BRCA genetic mutationCDC says, ‘There’s lots of flu in lots of places.’ And it’s not going away...
Source: Washington Post: To Your Health - January 16, 2018 Category: Consumer Health News Source Type: news

Roles of BCCIP Deficiency in Mammary Tumorigenesis Roles of BCCIP Deficiency in Mammary Tumorigenesis
New research helps uncover how BCCIP protein deficiency modulates breast cancer development.Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 16, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

FDA Approves Olaparib for Patients with Metastatic Breast Cancer and BRCA Mutation
The FDA has expanded the approval of olaparib (Lynparza) for patients with metastatic breast cancer who have a germline BRCA genetic mutation. Olaparib, a PARP... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 16, 2018 Category: Primary Care Source Type: news

Two Agents Offer Similar pCR Rates in ETNA Breast Cancer Trial (CME/CE)
(MedPage Today) -- Tumor subtype most significant factor for response among ERBB/HER2-negative patients (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - January 15, 2018 Category: Hematology Source Type: news

NHS breast cancer screening not offered to trans men
Women who believe they are men are not being offered routine NHS screening for breast and cervical cancer but men living as women are being invited for cervical smear tests. (Source: the Mail online | Health)
Source: the Mail online | Health - January 15, 2018 Category: Consumer Health News Source Type: news

Young-Onset Breast Cancer Survival Unaffected by BRCA Status (CME/CE)
(MedPage Today) -- But exception seen in triple-negative disease (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - January 13, 2018 Category: OBGYN Source Type: news

Teens are daring each other to eat Tide pods. We don ’ t need to tell you that ’ s a bad idea.
First, it was the “gallon challenge” and the “cinnamon challenge.” Then some teenagers started playing the “bath-salt challenge.” They have dared each other to pour salt in their hands and hold ice till it burns, douse themselves in rubbing alcohol and set themselves ablaze, and throw boiling water on unsuspecting peers. Now videos circulating on […]Related:CDC postpones session on ‘preparing for the unthinkable’: a nuclear blastFirst treatment approved for breast cancer with BRCA genetic mutationCDC says, ‘There’s lots of flu in lots of places.’ And ...
Source: Washington Post: To Your Health - January 13, 2018 Category: Consumer Health News Source Type: news

Tumor Genetic Factors Linked to Poor Survival in Metastatic Triple-negative Breast Cancer Tumor Genetic Factors Linked to Poor Survival in Metastatic Triple-negative Breast Cancer
Increased cell-free DNA (cfDNA) tumor fraction and certain somatic copy number alterations (SCNAs) are associated with worse survival in women with metastatic triple-negative breast cancer (TNBC), according to results from a retrospective study.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 13, 2018 Category: Pathology Tags: Hematology-Oncology News Source Type: news

BRCA Breast Cancer Gene Doesn't Affect Patient Survival: Study
(Source: Cancercompass News: Breast Cancer)
Source: Cancercompass News: Breast Cancer - January 13, 2018 Category: Cancer & Oncology Source Type: news

FDA Approves First Drug for Tumors Tied to Breast Cancer Genes
(Source: Cancercompass News: Breast Cancer)
Source: Cancercompass News: Breast Cancer - January 13, 2018 Category: Cancer & Oncology Source Type: news

CDC postpones session on ‘ preparing for the unthinkable ’ : a nuclear blast
The Centers for Disease Control and Prevention has rescheduled a teaching session on the public health response to a nuclear blast that was supposed to take place Tuesday. The session, which was to feature presentations from U.S. experts on public health preparedness and response and radiation, included a session titled "Preparing for the Unthinkable." The […]Related:First treatment approved for breast cancer with BRCA genetic mutationCDC says, ‘There’s lots of flu in lots of places.’ And it’s not going away anytime soon.FDA warns against giving kids cough and cold medicines with co...
Source: Washington Post: To Your Health - January 12, 2018 Category: Consumer Health News Source Type: news

FDA approves first drug for inherited breast cancer
AstraZeneca PLC's Lynparza is for patients with inherited BRCA gene mutations ​ who have undergone chemotherapy (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - January 12, 2018 Category: Consumer Health News Source Type: news

FDA Approves Lynparza (olaparib tablets) for Germline BRCA-Mutated Metastatic Breast Cancer
January 12, 2018 -- The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - January 12, 2018 Category: Drugs & Pharmacology Source Type: news

US OKs 1st drug aimed at women with inherited breast cancer
U.S. regulators have approved the first drug aimed at breast cancer patients who have an inherited mutation in the BRCA gene (Source: ABC News: Health)
Source: ABC News: Health - January 12, 2018 Category: Consumer Health News Tags: Health Source Type: news

CDC says, ‘There ’ s lots of flu in lots of places. ’ And it ’ s not going away anytime soon.
A nasty flu season is in full swing across the United States, with a sharp increase in the number of older people and young children getting hospitalized, federal health officials said Friday. The latest weekly data from the Centers for Disease Control and Prevention show influenza has spread across the country. “Flu is everywhere in the United States […]Related:First treatment approved for breast cancer with BRCA genetic mutationFDA warns against giving kids cough and cold medicines with codeine or hydrocodoneNew study on abortion pill shows high success, low rate of complications (Source: Wash...
Source: Washington Post: To Your Health - January 12, 2018 Category: Consumer Health News Source Type: news

Olaparib OK'd for Metastatic Breast Ca with Mutated BRCA
(MedPage Today) -- First PARP inhibitor to win breast cancer indication (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - January 12, 2018 Category: American Health Source Type: news

BRCA Breast Cancer Gene Doesn't Affect Survival
BRCA mutations are inherited and increase the risk of breast and ovarian cancers. Between 45 percent and 90 percent of women with a BRCA mutation develop breast cancer, compared with about 12.5 percent of women in the general population. (Source: WebMD Health)
Source: WebMD Health - January 12, 2018 Category: Consumer Health News Source Type: news

FDA Approves First Drug for Tumors Tied to Breast Cancer Genes
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 12, 2018 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pharmacy, Research, News, Source Type: news

BRCA Breast Cancer Gene Doesn ’ t Affect Patient Survival: Study
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 12, 2018 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Nursing, Oncology, Research, Surgery, News, Source Type: news

First treatment approved for breast cancer with BRCA genetic mutation
The Food and Drug Administration on Friday cleared the first treatment for patients with advanced breast cancer caused by BRCA mutations, which are genetic defects that raise the risk of malignancies. The drug, called Lynparza, already is approved for certain patients with advanced ovarian cancer associated with the same mutations. Richard Pazdur, director of the […]Related:FDA warns against giving kids cough and cold medicines with codeine or hydrocodoneNew study on abortion pill shows high success, low rate of complicationsHe was 21 and fit. He tried to push through the flu — and it killed him. (Source: Wash...
Source: Washington Post: To Your Health - January 12, 2018 Category: Consumer Health News Source Type: news

First Drug for BRCA Breast Cancer: Olaparib First Drug for BRCA Breast Cancer: Olaparib
Olaparib has achieved two firsts in breast cancer: it's the first PARP inhibitor and the first drug for patients carrying the BRCA mutation.FDA Approvals (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 12, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

FDA approves expanded use of AstraZeneca cancer drug
(Reuters) - The U.S. Food and Drug Administration said on Friday it has approved expanded use of AstraZeneca Plc's cancer drug Lynparza to include patients with metastatic breast cancer whose disease is associated with a mutation of the BRCA gene. (Source: Reuters: Health)
Source: Reuters: Health - January 12, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

U.S. FDA approves expanded use of AstraZeneca breast cancer drug
(Reuters) - The U.S. Food and Drug Administration said on Friday it has approved expanded use of AstraZeneca Plc's cancer drug Lynparza to include patients with metastatic breast cancer whose disease is associated with a mutation of the BRCA gene. (Source: Reuters: Health)
Source: Reuters: Health - January 12, 2018 Category: Consumer Health News Tags: healthNews Source Type: news