Immune evasion of stem cells in health and cancer
The Agudo lab is focused on the study of immune evasion of stem cells in both autoimmunity and cancer. Our goal is to identify targets to protect tissues for regeneration as well as mechanisms to ensure effective responses to immunotherapy in cancer patients. Dr. Agudo has recently discovered a population of quiescent cancer stem cells in breast cancer that survive during T cell attack and lead to resistance to immunotherapy.Air date: 11/29/2023 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - November 14, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
BME-SIG Lecture with Molly Schoichet
Drug discovery in cancer typically involves screening cells grown on 2-dimensional, hard plastic dishes; however, since human tissue is neither 2D nor plastic, this environment does not sufficiently emulate human disease. To overcome this limitation, we designed materials (i.e., hydrogels) for 3-dimensional cell culture with the goal of screening cells in an environment that mimics that of native tissue. With 3D cell culture, we gain an understanding of both cell invasion and cell viability, thereby providing insights that are inherently limited with traditional 2D cell culture. To achieve a suitable environment, we synthe...
Source: Videocast - All Events - April 24, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Heterogeneity of Breast Cancer Genomes: Going Beyond Therapy to Risk Assessment and Precision Healthcare
NIH Director ’ s Wednesday Afternoon Lecture SeriesThis is the annual Marshall W. Nirenberg Lecture. Speaker Olufunmilayo I. Olopade the consummate physician-scientist with sustained and impactful translational research in genetics that spans more than two decades. She is a pioneer in cancer genetics whose body of work has focused on the molecular genetics of breast cancer progression. Her seminal contributions have provided an understanding of the root causes of aggressive breast cancer in young women, especially young women of African ancestry across the Diaspora. Her laboratory was the first to describe recurrent BRCA...
Source: Videocast - All Events - May 23, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Researchers are working to improve radiologists ’ interpretation of AI data.
The wide range of applications for artificial intelligence alone are impressive. Researchers used mammograms of breast cancer to compare radiologists and AI assessments, to understand how AI and humans look at the images and find regions of potential concern. They learned, when you pair up human ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 12, 2022 Category: Science Source Type: video
Genomic Basis of Breast Cancer Progression in Blacks
This is the annual Marshall W. Nirenberg Lecture. Speaker Olufunmilayo I. Olopade the consummate physician-scientist with sustained and impactful translational research in genetics that spans more than two decades. She is a pioneer in cancer genetics whose body of work has focused on the molecular genetics of breast cancer progression. Her seminal contributions have provided an understanding of the root causes of aggressive breast cancer in young women, especially young women of African ancestry across the Diaspora. Her laboratory was the first to describe recurrent BRCA1 mutations in extended African American families wit...
Source: Videocast - All Events - November 27, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Artificial intelligence can boost breast cancer diagnoses.
Ultrasound breast exams, while an important tool, have caused numerous false breast cancer diagnoses. A team of NSF-funded researchers have developed an AI computer program trained to see distinctive patterns in thousands of ultrasound breast images, helping physicians to diagnose breast cancer ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - November 13, 2021 Category: Science Source Type: video
Advances in detecting, treating breast cancer
Deep Dive: From Google ' s AI for mammograms to clinical trial recruitment, digital health is tackling some of the biggest challenges in the breast cancer space. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - October 20, 2020 Category: Information Technology Tags: Population Health Women In Health IT Source Type: video
Race and the Molecular Biology Of Breast Cancer: A Pathologist ’ s View From the Bench to the Bedside
NIH Director ’ s Wednesday Afternoon Lecture Series
Dr. Gardner is a clinically trained pathologist that studies chromatin based-mechanism of transcriptional control in both cancers of lymphoid and epithelial origin. Recently we have refocused the efforts in my lab to define and reveal how alteration and/or disruption of gene regulation contributes to cancer incidence, evolution, and outcome. An essential and overarching goal of this effort is to translate the biological implications of these observations into principles and tenets that will have a broader impact on the molecular understanding of disease. The ultimate ob...
Source: Videocast - All Events - February 28, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Hereditary Cancer Mutation and Drug Development
NCI ’ s Center for Cancer Research (CCR) Grand Rounds
Dr. Pamela Munster is Co-Director of the Center for BRCA Research, a BRCA-focused clinical and research program at the Helen Diller Family Comprehensive Cancer Center at University of California San Francisco (UCSF). She received her medical degree from the University of Bern, Switzerland; completed her residency in Internal Medicine at Indiana University Medical Center then moved to Memorial Sloan-Kettering Cancer Center, New York for her oncology and hematology fellowship. Dr. Munster served at Memorial Sloan Kettering as a faculty member in the breast cancer progra...
Source: Videocast - All Events - February 3, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
TRACO 2019 - Breast cancer and Childhood cancer
Breast cancer and Childhood cancerFor more information go tohttps://www.cancer.gov/grants-training/training/resources-trainees/courses-fellowships/translational-research-clinical oncologyAir date: 10/21/2019 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - October 1, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
TRACO: Breast cancer and Childhood cancer
Breast cancer and Childhood cancerFor more information go tohttps://www.cancer.gov/grants-training/training/resources-trainees/courses-fellowships/translational-research-clinical oncologyAir date: 10/21/2019 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 16, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Postponed (Date to be Determined) - ORWH Women's Health Seminar Series: Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
The Tomosynthesis Mammographic Imaging Screening Trial (TMIST) is a randomized breast screening trial that will help researchers learn about the best ways to find breast cancer in women who have no symptoms. It compares two Food and Drug Administration-approved types of digital mammography: standard digital mammography (2-D) with a newer technology called tomosynthesis mammography (3-D). Researchers are doing this trial because they do not know if 3-D mammography is better than 2-D mammography for breast cancer screening.For more information go tohttps://orwh.od.nih.gov/Air date: 6/20/2019 1:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 18, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
Elizabeth A. Mittendorf, MD, PhD - On the Cusp of the Era of Immuno-Oncology in Triple-Negative Breast Cancer: Rational Strategies to Make the Most of Immunotherapies and Other Effective Treatment Modalities Throughout the Disease Continuum
Go online to PeerView.com/ZEX860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. Tremendous advances have been made in the treatment of many other subtypes of breast cancer, but treatment of triple-negative breast cancer (TNBC) has remained challenging. However, recent developments suggest that we are on the brink of a new era in TNBC therapy that now brings the novel class of cancer immunotherapies to this population of patients. In this activity, based on a recent live satellite symposium held in Dallas, Texas during the 20th Annual Meeting of The American Society of Br...
Source: Peerview CME/CE Video Podcast - Internal Medicine International - June 17, 2019 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video
Why don't we get more cancer: The importance of ECM Chromatin interactions in tissue-specificity and breast cancer
CCR Grand Rounds
Mina J. Bissel, Ph.D., is a Distinguished Scientist, the highest rank bestowed at Lawrence Berkeley National Laboratory (LBNL) and serves as Senior Advisor to the Laboratory Director on Biology. She is also Faculty of four Graduate Groups in UC Berkeley: Comparative Biochemistry, Endocrinology, Molecular Toxicology, and Bioengineering (UCSF/UCB joint program). Having challenged several established paradigms, Bissell is a pioneer in breast cancer research and her body of work has provided much impetus for the current recognition of the significant role that extracellular matrix (ECM) signaling and microenvi...
Source: Videocast - All Events - June 3, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video
