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Night Shifts Increase Breast Cancer Risk, Especially for Nurses Night Shifts Increase Breast Cancer Risk, Especially for Nurses
A meta-analysis confirms an increased risk for cancer, particularly breast cancer, in women working night shifts. The increase was'remarkable'in night nurses.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 8, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Athenex gets closer to clinical trials in China
Athenex Inc. (Nasdaq:ATNX) has taken another step forward in its efforts to bring an oral breast cancer drug to market in Asia.   The Buffalo-based biopharmaceutical firm received an acceptance from the Chinese Food& Drug Administration for an investigational new drug (IND) application for Oraxol, an oral version of its oral formulation of the chemotherapy formulation paclitaxel. It’s the next in a series of okays from FDA groups across the world, including the United States, South America,… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - January 8, 2018 Category: Biotechnology Authors: Tracey Drury Source Type: news

Medical News Today: Night shifts raise women's cancer risk
Women who work long-term night shifts may be at increased risk of developing cancer, especially breast cancer, reveals a new study. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 8, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Night shifts raise women's chances of cancer by 19%
Skin cancer was raised by 41%, breast cancer by 32% and stomach cancer by 18%, found Sichuan University in China. Night-shift nurses were found to have the biggest risk of breast cancer – 58%. (Source: the Mail online | Health)
Source: the Mail online | Health - January 8, 2018 Category: Consumer Health News Source Type: news

Gene test to predict breast cancer recurrence less cost effective in real world practice
(Georgetown University Medical Center) The most commonly used gene expression profile test, Oncotype DX ® , used to help predict breast cancer recurrence may not be as cost-effective as once thought, say a team of researchers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 8, 2018 Category: Cancer & Oncology Source Type: news

Medical News Today: What you should know about breast cancer in teens
A look at breast cancer in teens, a rare condition meaning statistics are hard to find. Included is detail on checking yourself and when to see a doctor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 7, 2018 Category: Consumer Health News Tags: Breast Cancer Source Type: news

Keto Diet Last, DASH First In New Diet Rankings
By Sandee LaMotte, CNN (CNN) — If you’re a fan of the “fat-burning” keto diet, you’ll be fired up about its ranking in the 2018 list of best diets from US News and World Report: It’s tied for last, along with the relatively unknown Dukan diet. Both stress eating a ton of protein and minimal carbs, putting the dieter into “ketosis,” when the body breaks down both ingested and stored body fat into ketones, which it uses as energy. People on such diets often deal with fatigue and light-headedness as they adjust to a lack of carbohydrates. Though the experts on the US News and Wo...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 6, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Weight Loss Source Type: news

Planmed Oy wins FDA nod for Clarity 2D digital mammography system
Planmed Oy said yesterday it won FDA approval for its Planmed Clarity 2D full-field digital mammography system. The company said the Clarity 2D system is designed to provide improved image quality, optimal ergonomics and usability for breast cancer screenings. The system also supports diagnostic work-up examinations and biopsy procedures, Planmed said. “We are excited that we can now introduce our fantastic Planmed Clarity 2D system in the United States. The system received the European Economic Area’s CE mark in early 2016 and it’s also available in Latin America, Africa, Australia, and Asia. The fe...
Source: Mass Device - January 5, 2018 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Imaging Regulatory/Compliance Women's Health Planmed Source Type: news

Take a Number: Cancer Deaths Continue a Steep Decline
More than two million patients have been saved by advances in diagnosis and treatment since 1991, according to new data. (Source: NYT Health)
Source: NYT Health - January 5, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Prostate Cancer Colon and Colorectal Cancer Breast Cancer Lung Cancer Pancreatic Cancer Deaths (Fatalities) American Cancer Society Source Type: news

Medical News Today: Just two sausages per week may raise breast cancer risk
Researchers suggest that eating just 9 grams of processed meats per day, or two sausages per week, could increase women's risk of breast cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 5, 2018 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Collaborative Global Study Casts New Light on Breast Cancer ’s Genetic Roots; Will Soon Provide Anatomic Pathologists and Clinical Laboratories with New Tools to Diagnose and Treat Cancer
In the same way that BRCA1 and BRCA2 mutations helped pathologists identify women with increased breast cancer risks in the late 1990s, this new study isolates an additional 72 mutations medical laboratories may soon use to diagnose breast cancer and assess risk factors For 20 years genetic scientists, anatomic pathologists, and medical laboratories have employed […] (Source: Dark Daily)
Source: Dark Daily - January 5, 2018 Category: Laboratory Medicine Authors: Jude Tags: Digital Pathology Laboratory Management and Operations Laboratory News Laboratory Pathology Laboratory Testing Management & Operations anatomic pathology breast cancer Cambridge University cancer screening Centre for Cancer Genetic Epi Source Type: news

Discuss all options for fertility preservation with patients, clinicians urged
And include transgender people and those with congenital conditions Related items fromOnMedica Fertility treatments may impact on breast cancer risk Infertility UK to expand trials of womb transplants Fertility preservation for girls with cancer ‘haphazard’ Patients face postcode lottery for IVF, new data shows (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 5, 2018 Category: UK Health Source Type: news

U.S. Cancer Deaths Steadily Dropping: Report
(Source: Cancercompass News: Breast Cancer)
Source: Cancercompass News: Breast Cancer - January 5, 2018 Category: Cancer & Oncology Source Type: news

What are the risks of risk-based breast cancer screening?
Could a breast cancer screening protocol based solely on a woman's risk factors...Read more on AuntMinnie.comRelated Reading: Personalized breast cancer screening study launches Risk-based mammo screening misses almost 60% of cancers New study to tackle personalized breast screening Does 'personalized screening' = healthcare rationing? Set your breast clinic apart with risk-based resources (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 4, 2018 Category: Radiology Source Type: news

Antitumor and Bone Effects of Everolimus in Breast Cancer Antitumor and Bone Effects of Everolimus in Breast Cancer
Why does this mTOR inhibitor have bone-protective effects?Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 4, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

New cancer model shows genomic link between early-stage and invasive breast cancer types
(University of Texas M. D. Anderson Cancer Center) A new genetic-based model may explain how a common form of early-stage breast cancer known as ductal carcinoma in situ (DCIS) progresses to a more invasive form of cancer say researchers at The University of Texas MD Anderson Cancer Center. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 4, 2018 Category: Biology Source Type: news

Breast size dissatisfaction affects self-examination
(Anglia Ruskin University) New research shows that women who are dissatisfied with the size of their breasts are less likely to carry out regular self-examinations to screen for breast cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 4, 2018 Category: International Medicine & Public Health Source Type: news

Immunotherapy and a virus could cure breast cancer
Breakthrough research by scientists at Ottawa University, Canada, showed the pairing cured up to 90 per cent of mice plagued by triple negative breast cancer - deemed the deadliest form. (Source: the Mail online | Health)
Source: the Mail online | Health - January 3, 2018 Category: Consumer Health News Source Type: news

Immune Cells Linked to Very Early Spread of Breast Cancer Immune Cells Linked to Very Early Spread of Breast Cancer
Normal immune cells that live near milk ducts in healthy breast tissue may play a key role in helping early breast cancer cells leave the breast for other parts of the body, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 3, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Could THIS combination cure breast cancer?
Breakthrough research by scientists at Ottawa University, Canada, showed the pairing cured up to 90 per cent of mice plagued by triple negative breast cancer - deemed the deadliest form. (Source: the Mail online | Health)
Source: the Mail online | Health - January 3, 2018 Category: Consumer Health News Source Type: news

Novartis Kisqali ® received FDA Breakthrough Therapy designation for initial endocrine-based treatment in premenopausal women with HR+/HER2- advanced breast cancer
Novartis today announced Kisqali® (ribociclib) received US Food and Drug Administration (FDA) Breakthrough Therapy designation for initial endocrine-based treatment of pre- or perimenopausal women with hormone-receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer in combination with tamoxifen or an aromatase inhibitor. (Source: World Pharma News)
Source: World Pharma News - January 3, 2018 Category: Pharmaceuticals Tags: Featured Novartis Business and Industry Source Type: news

ACR calls for summer radiology internship applications
The American College of Radiology (ACR) is accepting applications from first-year...Read more on AuntMinnie.comRelated Reading: ACR revises Appropriateness Criteria ACR names 2018 gold medalists ACR releases breast cancer screening criteria ACR updates Appropriateness Criteria Hillman to step down as editor of JACR (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 3, 2018 Category: Radiology Source Type: news

Novartis breast cancer therapy gets FDA breakthrough designation
ZURICH (Reuters) - Novartis's Kisqali (ribociclib) has won U.S. Food and Drug Administration breakthrough therapy designation for treating some breast cancer patients, the Swiss drugmaker said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - January 3, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Could viruses take cancer immunotherapy to the next level?
(The Ottawa Hospital) Immunotherapy, which helps the body's immune system attack cancer, has revolutionized treatment for cancers such as melanoma and leukemia. However, many other kinds of cancer remain resistant. A new study suggests that a combination of two immunotherapies (oncolytic viruses and checkpoint inhibitors) could be much more successful. This combination could cure 60-90 percent of mice in aggressive breast cancer models. Human trials are ongoing, in other kinds of cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 3, 2018 Category: Cancer & Oncology Source Type: news

Could viruses take cancer immunotherapy to the next level?
(Alliance for Cancer Gene Therapy) A study published in Science Translational Medicine shows a combination of oncolytic viruses and checkpoint inhibitors successfully treated breast cancer with a 60-90 percent cure rate. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 3, 2018 Category: Cancer & Oncology Source Type: news

Trastuzumab: No negative impact on cardiac function
(NRG Oncology) Long-term follow-up results of the NRG Oncology trial NSABP B-31 have shown that the addition of trastuzumab to adjuvant chemotherapy does not negatively affect cardiac function in women with node-positive, human epidermal growth factor receptor 2 (HER2)-positive, early-stage breast cancer who survive without cancer recurrence. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 3, 2018 Category: International Medicine & Public Health Source Type: news

Processed meat 'cancer risk' in older women
New study shows older women who eat processed meats have raised breast cancer risk Related items fromOnMedica Mediterranean diet cuts womb cancer risk Diverticulitis in men linked to high red meat intake Processed meat linked to worsening asthma symptoms Breast cancer risk lower with Mediterranean diet plus oil Dietary intake of veg linked to lower risk of ER-negative breast cancer (Source: OnMedica Latest News)
Source: OnMedica Latest News - January 3, 2018 Category: UK Health Source Type: news

Serum-DNA Methylation Patterns Might Allow Early Identification of Breast, Ovarian Cancer Serum-DNA Methylation Patterns Might Allow Early Identification of Breast, Ovarian Cancer
Methylation patterns in serum DNA might allow for the early identification of disseminated breast cancer and ovarian cancer, according to two new reports from the U.K.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 2, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

CDC Confirms Persisting Racial Disparities in Cancer Survival
Survival disparities for black patients with ovarian, colon, and breast cancer and childhood ALL suggest a need for efforts toward improved screening and treatment adherence in this population. (Source: CancerNetwork)
Source: CancerNetwork - January 2, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Tags: News Practice & Policy Source Type: news

Immune cells linked to very early spread of breast cancer
(Reuters Health) - Normal immune cells that live near milk ducts in healthy breast tissue may play a key role in helping early breast cancer cells leave the breast for other parts of the body, researchers say. (Source: Reuters: Health)
Source: Reuters: Health - January 2, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Will Immunotherapy Be a PANACEA for Breast Cancer? Will Immunotherapy Be a PANACEA for Breast Cancer?
Drs Kathy Miller and Sherene Loi discuss advances in immunotherapy for breast cancer, particularly in HER2-positive disease and TNBC.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 2, 2018 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

PALOMA-3: Fulvestrant, Palbociclib in Advanced Breast Cancer PALOMA-3: Fulvestrant, Palbociclib in Advanced Breast Cancer
New research finds that palbociclib added to fulvestrant improves progression-free survival in Asian patients with metastatic breast cancer.Journal of Global Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 2, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Research finds that minorities don't trust the system, refuse to share samples for genetic cancer studies
(Natural News) Research shows that minorities tend to be underrepresented in precision medicine studies like those of breast cancer, as the willingness to provide samples depends on oncologist engagement or religion, an article in Springer.com reports. Precision medicine is defined as data-driven treatment that takes into account individual factors such as genes, environment, and personal... (Source: NaturalNews.com)
Source: NaturalNews.com - January 2, 2018 Category: Consumer Health News Source Type: news

FDA News: Diabetic Foot Ulcers, Severe Hypotension, and Breast Cancer
Here is some of the latest news from the FDA: Diabetic foot ulcers: The agency has cleared for marketing the first shock wave system to... (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 2, 2018 Category: Primary Care Source Type: news

Ganetespib, Paclitaxel, Trastuzumab for HER2+ Breast Cancer Ganetespib, Paclitaxel, Trastuzumab for HER2+ Breast Cancer
Early research finds that ganetespib added to paclitaxel and trastuzumab shows promise for heavily pretreated patients with HER2+ breast cancer.Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 2, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Genetic Variants and Contralateral Breast Cancer Risk Genetic Variants and Contralateral Breast Cancer Risk
Are the genomic variants known to increase risk of first primary breast cancer also associated with the development of contralateral breast cancer?Journal of the National Cancer Institute (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 2, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Immune cells play key role in early breast cancer metastasis even before a tumor develops
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature Communications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 2, 2018 Category: International Medicine & Public Health Source Type: news

Why are women still being denied breast reconstruction?
Having operated on thousands of women with breast cancer, few people are as familiar with its realities as RUTH WATERS. (Source: the Mail online | Health)
Source: the Mail online | Health - January 2, 2018 Category: Consumer Health News Source Type: news

Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer
Through the tumor necrosis factor (TNF) receptor type II (TNFR2), TNF preferentially activates, expands, and promotes the phenotypic stability of CD4+Foxp3+ regulatory T (Treg) cells. Those Treg cells that have a high abundance of TNFR2 have the maximal immunosuppressive capacity. We investigated whether targeting TNFR2 could effectively suppress the activity of Treg cells and consequently enhance the efficacy of cancer immunotherapy. We found that, relative to a suboptimal dose of the immunostimulatory Toll-like receptor 9 ligand CpG oligodeoxynucleotide (ODN), the combination of the suboptimal dose of CpG ODN with the TN...
Source: Signal Transduction Knowledge Environment - January 2, 2018 Category: Science Authors: Nie, Y., He, J., Shirota, H., Trivett, A. L., Yang, D., Klinman, D. M., Oppenheim, J. J., Chen, X. Tags: STKE Research Articles Source Type: news

The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division
We report protein palmitoylation as a key mechanism for the asymmetric partitioning of the cell fate determinants Numb and β-catenin through the activity of the depalmitoylating enzyme APT1. Using point mutations, we showed that specific palmitoylated residues on Numb were required for its asymmetric localization. By live-cell imaging, we showed that reciprocal interactions between APT1 and the Rho family GTPase CDC42 promoted the asymmetric localization of Numb and β-catenin to the plasma membrane. This, in turn, restricted Notch- or Wnt-responsive transcriptional activity to one daughter cell. Moreover, we show...
Source: Signal Transduction Knowledge Environment - January 2, 2018 Category: Science Authors: Stypulkowski, E., Asangani, I. A., Witze, E. S. Tags: STKE Research Articles Source Type: news

Are women turning to natural cures? New study shows chemotherapy treatments for early stage breast cancer are declining
(Natural News) Rates of breast cancer may be on the rise, but the number of women with the condition who opt for conventional chemotherapy as treatment is reportedly in serious decline. New research published in the Journal of the National Cancer Institute suggests that an increasing number of breast cancer patients are wary of the... (Source: NaturalNews.com)
Source: NaturalNews.com - January 1, 2018 Category: Consumer Health News Source Type: news

For Low-Level HER2 Breast Cancer, Trastuzumab Is a No-Go For Low-Level HER2 Breast Cancer, Trastuzumab Is a No-Go
Although the study didn't turn out as hoped, NSABP B-47 will help inform the decision of whether patients with low-level HER2 breast cancer should receive trastuzumab.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 29, 2017 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news

Cancer Risk Rises With More CV Procedures in Congenital-HD Adults Cancer Risk Rises With More CV Procedures in Congenital-HD Adults
The independently raised cancer risk went up with cumulative radiation exposure in an aging cohort of>24,000; breast cancer was the most common malignancy in women, genitourinary cancer in men.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 29, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

Mylan breast cancer drug approved in Brazil
Mylan NV on Friday said it had received the green light in Brazil for a treatment for breast cancer that it developed with a partner in the country. Biocon LTD (BSE: BIOCON) and Mylan (Nasdaq: MYL) co-developed biosimilar Trastuzumab, which treats overexpressing HER2-positive metastatic breast cancer, HER2-positive early stage breast cancer and HER2-positive advanced gastric cancer. It will be sold in Brazil in Brazil as Zedora by Libbs Farmac eutica. "The approval of Zedora, Brazil's first Trastuzumab… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 29, 2017 Category: Pharmaceuticals Authors: Paul J. Gough Source Type: news

Mylan-Biocon's breast cancer biosimilar gets ANVISA nod
Biosimilar trastuzumab, indicated for breast cancer treatment, has been co-developed by Biocon and Mylan. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - December 29, 2017 Category: Pharmaceuticals Source Type: news

App Helps Women Assess Risk For Breast Cancer
PEABODY (CBS) – Many women have an increased risk of breast cancer and don’t even know it. But as Dr. Mallika Marshall reports, one local hospital is offering a new tool to women undergoing routine mammograms that helps them assess their risk. “My sibling and I joke we have cancer on mom’s side,” said 46-year-old Gia Leach of Lynnfield. “We’re just wondering what kind it’s going to be that’s going to get to us.” Leach has a strong family history of cancer, including breast, so she’s good about getting her routine mammograms. She had her last one in February....
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - December 29, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Dr. Mallika Marshall Lahey Health Peabody Source Type: news

Acupuncture found to be effective at relieving side effects of traditional treatments in breast cancer patients, according to study
(Natural News) Traditional Chinese Medicine (TCM) has been around for years – centuries even – because of its natural approach to human health. An area of TCM that’s getting renown even from Western medicine is acupuncture and based on the findings of a study made by researchers at the NewYork-Presbyterian and Columbia University Irving Medical Center, it could... (Source: NaturalNews.com)
Source: NaturalNews.com - December 28, 2017 Category: Consumer Health News Source Type: news

Help mitigate the toxic effects of traditional cancer treatments with diet: Soy, cruciferous vegetables associated with fewer side effects
(Natural News) Conventional breast cancer treatment is certainly no walk in the park – although taking a walk in the park certainly can help take the edge off the symptoms, if you’re feeling up to it. If you’re not, however, you can help to mitigate the effects by making some smart dietary choices, according to... (Source: NaturalNews.com)
Source: NaturalNews.com - December 28, 2017 Category: Consumer Health News Source Type: news

Ex vivo Natural Killer Cells Against Breast Cancer Cells Ex vivo Natural Killer Cells Against Breast Cancer Cells
Research finds that expanded natural killer cells from breast cancer patients may demonstrate cytotoxic activity.Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 28, 2017 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Does Breast Cancer Risk REACT to Celecoxib? Does Breast Cancer Risk REACT to Celecoxib?
Does this COX-2 inhibitor alter breast cancer risk? Dr Kathy Miller discusses the results of the REACT trial with its primary investigator, Dr Charles Coombes.Medscape Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 27, 2017 Category: Consumer Health News Tags: Hematology-Oncology Commentary Source Type: news