Fertility-Sparing Surgery for Ovarian Cancer
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published in English ...
Source: Clinical Breast Cancer - September 28, 2021 Category: Cancer & Oncology Authors: Geoffroy Canlorbe Nathalie Chabbert-Buffet Catherine Uzan Source Type: research

Fertility-Sparing Surgery for Ovarian Cancer
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published in English ...
Source: Clinical Genitourinary Cancer - September 28, 2021 Category: Cancer & Oncology Authors: Geoffroy Canlorbe Nathalie Chabbert-Buffet Catherine Uzan Source Type: research

Fertility-Sparing Surgery for Ovarian Cancer
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published in English ...
Source: Clinical Breast Cancer - September 28, 2021 Category: Cancer & Oncology Authors: Geoffroy Canlorbe Nathalie Chabbert-Buffet Catherine Uzan Source Type: research

Fertility-Sparing Surgery for Ovarian Cancer
J Clin Med. 2021 Sep 18;10(18):4235. doi: 10.3390/jcm10184235.ABSTRACT(1) Background: although most patients with epithelial ovarian cancer (EOC) undergo radical surgery, patients with early-stage disease, borderline ovarian tumor (BOT) or a non-epithelial tumor could be offered fertility-sparing surgery (FSS) depending on histologic subtypes and prognostic factors. (2) Methods: we conducted a systematic review to assess the safety and fertility outcomes of FSS in the treatment of ovarian cancer. We queried the MEDLINE, PubMed, Cochrane Library, and Cochrane ("Cochrane Reviews") databases for articles published in English ...
Source: Clinical Genitourinary Cancer - September 28, 2021 Category: Cancer & Oncology Authors: Geoffroy Canlorbe Nathalie Chabbert-Buffet Catherine Uzan Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research

Decreased Gastric Gland Mucin-specific < em > O < /em > -glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours
Acta Histochem Cytochem. 2021 Aug 25;54(4):115-122. doi: 10.1267/ahc.21-00032. Epub 2021 Jul 7.ABSTRACTOvarian primary mucinous tumours (OPMTs) show an adenoma-borderline-carcinoma sequence with gastrointestinal metaplasia. Gastric gland mucin-specific O-glycans are unique with an α1,4-linked N-acetylglucosamine (αGlcNAc) residue attached to mucin 6 (MUC6). Although αGlcNAc is expected to be expressed in OPMTs, the relationship between αGlcNAc expression and OPMT progression remains unknown. Here, we analysed 104 areas of benign mucinous tumours (benign), 55 areas of borderline mucinous tumours (borderline), and 18 are...
Source: Acta Histochemica et Cytochemica - September 13, 2021 Category: Biochemistry Authors: Ayumi Ohya Hisanori Matoba Yasunari Fujinaga Jun Nakayama Source Type: research