The inspirational reason girl, 7, who lost her leg to cancer had her limb attached BACKWARDS
Amelia Eldred, 7, from Tamworth, had her left leg amputated because of a rare form of bone cancer, but her lower leg has been reattached so her ankle can act as a knee when she gets a prosthetic leg. (Source: the Mail online | Health)
Source: the Mail online | Health - April 20, 2018 Category: Consumer Health News Source Type: news

Morris Animal Foundation awards $775K to test osteosarcoma immunotherapy vaccine in dogs
(Morris Animal Foundation) Morris Animal Foundation has awarded a $775,000 grant to the University of Pennsylvania to test a vaccine that could improve longevity and quality of life for dogs with the deadly bone tumor, osteosarcoma. The research team will conduct clinical trials to evaluate a novel immunotherapy treatment which combines a molecule expressed by cancer cells with a modified live form of the bacteria Listeria monocytogenes. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 17, 2018 Category: Biology Source Type: news

Pregnant woman, 29, diagnosed with terminal cancer after scan 17 weeks into her first pregnancy
Laura King, a nursery director from Surrey, beat breast cancer in 2017. After the all-clear, she and her husband decided to start a family. Weeks later, she was diagnosed with secondary bone cancer. (Source: the Mail online | Health)
Source: the Mail online | Health - April 13, 2018 Category: Consumer Health News Source Type: news

A potential new therapeutic target for Ewing sarcoma
(IDIBELL-Bellvitge Biomedical Research Institute) IDIBELL researchers correlate EphA2 membrane receptor with the metastatic capacity of tumors in Ewing sarcoma.Ewing sarcoma is the second most frequent bone cancer among children and adolescents, and it is characterized by its aggressiveness and tendency to metastasize.Researchers are currently working on nanoengineering a molecule capable of blocking EphA2 and deliver drugs in a targeted manner.Research was possible thanks to the backing of Alba P é rez Foundation. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 5, 2018 Category: Cancer & Oncology Source Type: news

Greehey Institute team finds link between BRCA1 and Ewing sarcoma
(University of Texas Health Science Center at San Antonio) Scientists with the Greehey Children's Cancer Research Institute at UT Health San Antonio have discovered a surprising connection between a breast cancer protein, BRCA1, and a pediatric cancer called Ewing sarcoma. Their findings were made public March 7 online in the journal Nature. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 7, 2018 Category: Cancer & Oncology Source Type: news

PET imaging could help personalize cancer treatment
Researchers have developed a same-day, noninvasive PET imaging approach to...Read more on AuntMinnie.comRelated Reading: FDG-PET/CT predicts outcomes in pediatric osteosarcoma Artificial intelligence guides lower PET tracer dose PET tracer could better assess lung ailments SNMMI posts criteria for somatostatin receptor PET Deep learning analyzes PET for signs of dementia (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - March 2, 2018 Category: Radiology Source Type: news

Gemcitabine Plus Sirolimus for Osteosarcoma Gemcitabine Plus Sirolimus for Osteosarcoma
The combination of gemcitabine and sirolimus may be a safe and effective option for patients with relapsed unresectable osteosarcoma.Annals of Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 23, 2018 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Scientists tackle the aberrant epigenetic programming underlying childhood cancers
(Write Science Right) Researchers at UFRGS and the US NIH have targeted proteins that regulate chromatin in Ewing sarcoma cells, hindering malignant tumor growth. They induced chromatic relaxation by treating the cells with histone deacetylase inhibitors, reducing expression of the EWSR1-FLI-1 oncogene and other pluripotency/cell viability genes, while impairing sarcoma cell survival and growth. Decreased survival of stem-like cancer cells and re-expression of a neuronal differentiation marker were also observed. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2018 Category: International Medicine & Public Health Source Type: news

Unique research approach finds FDA-approved drug shuts down Ewing sarcoma cells in lab
(Georgetown University Medical Center) Based on a novel approach to drug discovery, researchers at Georgetown Lombardi Comprehensive Cancer Center say an agent approved to treat a type of leukemia might also help young people with a much rarer and aggressive form of cancer, Ewing sarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 30, 2018 Category: Cancer & Oncology Source Type: news

Cancer Researchers Hit Bullseye with New Drug Target for Ewing Sarcoma
The revelation brings a surge of hope to the field of pediatric oncology which has long been challenged to find new drugs against childhood cancers (Source: Disabled World)
Source: Disabled World - January 26, 2018 Category: Disability Tags: Cancer - Tumors Source Type: news

Alex Huang, M.D., Ph.D., receives $450,000 from Pediatric Cancer Research Foundation
(Case Western Reserve University) Leading cancer researcher, Alex Huang M.D., Ph.D., has received a $450,000 Basic Science grant from Pediatric Cancer Research Foundation to study targeted approaches for effectively eliminating metastatic osteosarcoma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 25, 2018 Category: International Medicine & Public Health Source Type: news

Cancer researchers hit a bullseye with new drug target for Ewing sarcoma
(Boston Children's Hospital) Kimberly Stegmaier of Dana-Farber/Boston Children's Cancer and Blood Disorders Center and collaborators have found that Ewing sarcoma cells die if an enzyme called CDK12 is knocked out genetically or chemically inhibited. What's more, when a CDK12 inhibitor is combined with another drug, called a PARP inhibitor, the two drugs double down to deliver a lethal punch to Ewing sarcoma cells. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 25, 2018 Category: Biology Source Type: news

FDG-PET/CT predicts outcomes in pediatric osteosarcoma
The best way to predict a good outcome for pediatric patients with osteosarcoma...Read more on AuntMinnie.comRelated Reading: UC Davis group reports progress on total-body PET/CT FDA issues guidance on lowering pediatric x-ray dose FDG-PET, DWI-MRI help predict osteosarcoma chemo response FDG-PET/CT a good option for imaging pediatric osteosarcoma (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 19, 2018 Category: Radiology Source Type: news

Promising Experimental Drug Treating Dogs With Cancer
NORTH GRAFTON (CBS) – When it comes to cancer research, dogs just might be the key to unlock vital clues needed to find a cure. Veterinarians in central Massachusetts are excited about some recent results and it’s also making for some extremely thankful pet owners. “They gave me my best friend back and they gave him more time, quality time,” said Edward Sloan, whose dog, Dozer, a 7-year-old bull mastiff, became sick last fall. “All of sudden he went blind, overnight,” Sloan said. “He was scared.  He was sad.” Dozer had cancer. Dozer, a 7-year-old bull mastiff, is being trea...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 13, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Cancer Dr. Mallika Marshall Source Type: news

Molecular imaging technique identifies lung nodules for resection in osteosarcoma patient
(SPIE--International Society for Optics and Photonics) Utility of near-infrared molecular imaging in a patient undergoing pulmonary metastasectomy for osteosarcoma has been reported by researchers from Perelman School of Medicine at the University of Pennsylvania and Purdue University. The work is reported in an article in the Journal of Biomedical Optics published this week by SPIE, the international society for optics and photonics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 5, 2018 Category: International Medicine & Public Health Source Type: news