Four-year-old was diagnosed with cancer after doctors dismissed his weeping eye as a cold 
Harri Cooke, from Tewkesbury, Gloucestershire, was a happy toddler before his mum, Carly, 33, noticed he had a weeping eye. He was later diagnosed with Ewing’s Sarcoma (Source: the Mail online | Health)
Source: the Mail online | Health - November 21, 2018 Category: Consumer Health News Source Type: news

Man is forced to have his leg amputated after developing cancer
Matthew King, from North Yorkshire, was rushed to Darlington Memorial Hospital where he was diagnosed with Ewing Sarcoma -  a rare form of cancer that typically affects young men. (Source: the Mail online | Health)
Source: the Mail online | Health - November 20, 2018 Category: Consumer Health News Source Type: news

Man is forced to have his leg amputated after developing cancer
Matthew King, from North Yorkshire, was rushed to Darlington Memorial Hospital where he was diagnosed with Ewing Sarcoma - a rare form of cancer that typically affects young men. (Source: the Mail online | Health)
Source: the Mail online | Health - November 20, 2018 Category: Consumer Health News Source Type: news

Alex Huang, M.D., Ph.D., awarded $1.35 million to conduct lifesaving childhood cancer research
(Case Western Reserve University) Leading cancer researcher, Alex Huang M.D., Ph.D., has been awarded a three-year, $1.35 million grant from the St. Baldrick's Foundation and the Osteosarcoma Collaborative to develop new ways to treat osteosarcoma, a rare cancer that begins in the bone. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 8, 2018 Category: International Medicine & Public Health Source Type: news

Are We Underdosing Patients With Ewing Sarcoma?
A new study evaluated whether busulfan and melphalan improve EFS and OS when given after vincristine, ifosfamide, doxorubicin, and etoposide induction. (Source: CancerNetwork)
Source: CancerNetwork - October 25, 2018 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

Time to Rethink Chemo Doses in High-Risk, Localized Ewing Sarcoma?
A new study evaluated whether busulfan and melphalan improve EFS and OS when given after vincristine, ifosfamide, doxorubicin, and etoposide induction. (Source: CancerNetwork)
Source: CancerNetwork - October 23, 2018 Category: Cancer & Oncology Authors: John Schieszer Source Type: news

WATCH: Purdue superfan inspires team's unlikely win over Ohio State
Tyler Trent, 20, a Purdue sophomore, has terminal bone cancer and was invited by the team to address the players in the locker room. (Source: ABC News: Health)
Source: ABC News: Health - October 22, 2018 Category: Consumer Health News Tags: GMA Source Type: news

New clinical trials seek treatments for canine cancers, may offer clues on human cancers
(Tufts University) Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 11, 2018 Category: Cancer & Oncology Source Type: news

'My jaw was reconstructed from my shoulder'
When Jen Taylor was diagnosed with bone cancer, she underwent 16 hours of surgery. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 28, 2018 Category: Consumer Health News Source Type: news

Brave eight-year-old boy battles second bout of brain cancer since he was just two
Jaxon Dugger, eight, from Hollis, Oklahoma, was fist diagnosed with Ewing sarcoma when he was just two years old. Three months after being declared cancer-free, his tumor returned. (Source: the Mail online | Health)
Source: the Mail online | Health - September 12, 2018 Category: Consumer Health News Source Type: news

Dancer, 12, who lost leg to rare bone cancer undergoes operation to turn her ankle into a KNEE
Delaney Unger, 12, from Selden, New York, was diagnosed with osteosarcoma, a type of bone cancer, in December 2016 and was told that part of her leg would need to be amputated. (Source: the Mail online | Health)
Source: the Mail online | Health - September 10, 2018 Category: Consumer Health News Source Type: news

Children's bone cancers could remain hidden for years before diagnosis
(Wellcome Trust Sanger Institute) Scientists have discovered that some childhood bone cancers start growing years before they are diagnosed. Researchers at the Wellcome Sanger Institute, UK and Hospital for Sick Children (SickKids), Canada discovered large-scale genetic rearrangements in Ewing Sarcomas and other children's cancers, and showed these can take years to form. The study in Science will help unravel causes of childhood cancers and could help find ways to diagnose and treat these cancers earlier in the future. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 30, 2018 Category: Cancer & Oncology Source Type: news

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors
Sarcomas are cancers of the bone and soft tissue often defined by gene fusions. Ewing sarcoma involves fusions between EWSR1, a gene encoding an RNA binding protein, and E26 transformation-specific (ETS) transcription factors. We explored how and when EWSR1-ETS fusions arise by studying the whole genomes of Ewing sarcomas. In 52 of 124 (42%) of tumors, the fusion gene arises by a sudden burst of complex, loop-like rearrangements, a process called chromoplexy, rather than by simple reciprocal translocations. These loops always contained the disease-defining fusion at the center, but they disrupted multiple additional genes....
Source: ScienceNOW - August 30, 2018 Category: Science Authors: Anderson, N. D., de Borja, R., Young, M. D., Fuligni, F., Rosic, A., Roberts, N. D., Hajjar, S., Layeghifard, M., Novokmet, A., Kowalski, P. E., Anaka, M., Davidson, S., Zarrei, M., Id Said, B., Schreiner, L. C., Marchand, R., Sitter, J., Gokgoz, N., Brun Tags: Genetics, Medicine, Diseases, Online Only r-articles Source Type: news

Modern myths about cancer – from ‘chemicals’ in food to wifi
The idea that lifestyle changes have made the disease more common is a gross exaggeration – but increasingly prevalent. We separate fact from fictionCancer is not up there withthe most likely explanations for what caused the mass extinction 66m years ago of the T rex and the triceratops. That said, at leastone species of dinosaur suffered from blood-vessel tumours – anda 1.7m-year-old toe with bone cancer was discovered in 2016 at a South African world heritage site.Cancer may have been more common in ancient times than we will ever know, because fossilisation will have obliterated most evidence of the disease. However...
Source: Guardian Unlimited Science - August 20, 2018 Category: Science Authors: Naomi Elster Tags: Cancer research Health & wellbeing Society Medical research Science Life and style Source Type: news

MGH team defines the mechanisms of action of key genetic abnormality in Ewing sarcoma
(Massachusetts General Hospital) A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma -- the second most common bone cancer in children and young adults -- unleashes tumor growth. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 2, 2018 Category: Cancer & Oncology Source Type: news