The adverse and beneficial effects of polyphenols in green and black teas < em > in vitro < /em > and < em > in vivo < /em >
In this study, we investigated the effects of eight green tea samples (G1-G8) and eight black tea samples (R1-R8) from Camellia sinensis, the most popular teas in Asian culture, on RSC96 Schwann neural cells and embryonic cardiomyocyte H9c2 cells. The results showed that the IC50 (mg/ml, weight/volume) of both tea types were inversely proportional to their polyphenol content, suggesting a relationship between toxicity and polyphenol levels in both green and black tea. Interestingly, green teas generally have higher polyphenol content than black teas. We also assessed the protective effects of tea in vitro by pretreating ce...
Source: International Journal of Medical Sciences - October 3, 2023 Category: Biomedical Science Authors: Mei-Hui Wu Jer-Yuh Liu Fang Ling Tsai Jyuan-Jen Syu Ciao-Sin Yun Liang-Ying Chen Je-Chiuan Ye Source Type: research

Research progress on alternative kombucha substrate transformation and the resulting active components
This article aimed to bridge this gap by providing an in-depth review of the biological transformation pathways of kombucha metabolites and alternative substrates. The review offers valuable insights into kombucha research, including substance metabolism and transformation, efficacy, pharmacological mechanism, and the purification of active components, offering direction and focus for further studies in this field. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - September 14, 2023 Category: Microbiology Source Type: research

Molecules, Vol. 28, Pages 5871: Microbial-Transferred Metabolites of Black Tea Theaflavins by Human Gut Microbiota and Their Impact on Antioxidant Capacity
In conclusion, the results contribute to a more comprehensive understanding of the microbial metabolites and antioxidant capacity of TFs. (Source: Molecules)
Source: Molecules - August 4, 2023 Category: Chemistry Authors: Li Sun You Su Kaiyin Hu Daxiang Li Huimin Guo Zhongwen Xie Tags: Article Source Type: research

Dissecting the role of microorganisms in tea production of different fermentation levels: a multifaceted review of their action mechanisms, quality attributes and future perspectives
AbstractTea is one of the most popular beverages worldwide, with several health benefits attributed for its rich chemical composition and further associated with fermentation process to improve its quality attributes. Most tea types originate from the leaves ofCamellia sinensis with differences in fermentation levels yielding black tea, green tea, pouchong tea, oolong tea. Teas like pu-erh or kombucha to encompass both green and red types are further post-fermented. Tea fermentation is a traditional process involving physical, biochemical, and microbial changes which are associated with improved organoleptic characters, nu...
Source: World Journal of Microbiology and Biotechnology - July 29, 2023 Category: Microbiology Source Type: research

Optimization and synthesis of a novel sorbent composite based on magnetic chitosan-amine-functionalized bimetallic MOF for the simultaneous dispersive solid-phase microextraction of four aflatoxins in real water, herbal distillate, and food samples
Anal Bioanal Chem. 2023 Jul 29. doi: 10.1007/s00216-023-04842-0. Online ahead of print.ABSTRACTAflatoxins (AFs), an important category of pollutants, are formed in many foods and adversely affect human health. Therefore, their determination is critical to ensuring human food health. An efficient dispersive solid-phase microextraction technique was developed as a simple and straightforward sample preparation technique for determination of four aflatoxins using a high-performance liquid chromatography (HPLC) fluorescence detector. A novel efficient, green sorbent for extracting AFs was synthesized based on hydrothermal and c...
Source: Analytical and Bioanalytical Chemistry - July 28, 2023 Category: Chemistry Authors: Mahdi Ghorbani Majid Keshavarzi Maryam Pakseresht Parisa Mohammadi Alireza Shams Abouzar Mehraban Amir Ismailzadeh Source Type: research

Unravelling the anti-inflammatory and antioxidant effects of standardized green and black caffeinated coffee, tea, and their mixtures in an obese male rat model: Insights from biochemical, metabolomic, and histopathological analyses
This study aimed to discern altered metabolic pathways associated with obesity and to pinpoint metabolite biomarkers in serum of obese rats fed on high fructose diet using metabolomics. Further, the effect of standardized green versus black caffeinated aqueous extracts (tea and coffee) in controlling obesity and its comorbidities through monitoring relevant serum biomarkers viz. Leptin, adiponectin, spexin, malondialdehyde, total antioxidant capacity. Liver tissue oxidative stress (catalase, super oxide dismutase and glutathione) and inflammation (IL-1β and IL-6) markers were assessed for green coffee and its mixture with...
Source: Food and Chemical Toxicology - July 28, 2023 Category: Food Science Authors: Dina M El-Kersh Soheir E Kotob Naglaa M Ammar Ola Mohawed Hanaa H Ahmed Mohamed A Farag Source Type: research

Molecules, Vol. 28, Pages 5573: Ultra-High Adsorption Capacity of Core & ndash;Shell-Derived Magnetic Zeolite Imidazolate Framework-67 as Adsorbent for Selective Extraction of Theophylline
Molecules, Vol. 28, Pages 5573: Ultra-High Adsorption Capacity of Core&ndash;Shell-Derived Magnetic Zeolite Imidazolate Framework-67 as Adsorbent for Selective Extraction of Theophylline Molecules doi: 10.3390/molecules28145573 Authors: Ling-Xiao Chen Shi-Jun Yin Tong-Qing Chai Jia-Li Wang Guo-Ying Chen Xi Zhou Feng-Qing Yang A core&amp;ndash;shell-derived structural magnetic zeolite imidazolate framework-67 (Fe3O4-COOH@ZIF-67) nanocomposite was fabricated through a single-step coating of zeolite imidazolate framework-67 on glutaric anhydride-functionalized Fe3O4 nanosphere for the magnetic soli...
Source: Molecules - July 21, 2023 Category: Chemistry Authors: Ling-Xiao Chen Shi-Jun Yin Tong-Qing Chai Jia-Li Wang Guo-Ying Chen Xi Zhou Feng-Qing Yang Tags: Article Source Type: research

Theaflavin inhibits African swine fever virus replication by disrupting lipid metabolism through activation of the AMPK signaling pathway in virto
In this study, we aimed to investigate the anti-ASF activity of theaflavin (TF), a natural compound mainly isolated from black tea. We found that TF potently inhibited ASFV replication at non-cytotoxic concentrations ex vivo in primary porcine alveolar macrophages (PAMs). Mechanistically, we found that TF inhibited ASFV replication by acting on cells rather than interacting directly with ASFV to inhibit viral replication. Further, we found that TF upregulated the AMPK (5'-AMP-activated protein kinase) signaling pathway in ASFV-infected and uninfected cells, and treatment with the AMPK agonist MK8722 upregulated the AMPK si...
Source: Virus Research - June 29, 2023 Category: Virology Authors: Yang Chen Zhi Wei Zebu Song Hao Chang Yanchen Guo Yankuo Sun Heng Wang Zezhong Zheng Guihong Zhang Source Type: research

Theaflavin inhibits African swine fever virus replication by disrupting lipid metabolism through activation of the AMPK signaling pathway in virto
In this study, we aimed to investigate the anti-ASF activity of theaflavin (TF), a natural compound mainly isolated from black tea. We found that TF potently inhibited ASFV replication at non-cytotoxic concentrations ex vivo in primary porcine alveolar macrophages (PAMs). Mechanistically, we found that TF inhibited ASFV replication by acting on cells rather than interacting directly with ASFV to inhibit viral replication. Further, we found that TF upregulated the AMPK (5'-AMP-activated protein kinase) signaling pathway in ASFV-infected and uninfected cells, and treatment with the AMPK agonist MK8722 upregulated the AMPK si...
Source: Virus Research - June 29, 2023 Category: Virology Authors: Yang Chen Zhi Wei Zebu Song Hao Chang Yanchen Guo Yankuo Sun Heng Wang Zezhong Zheng Guihong Zhang Source Type: research

Microwave-assisted quick synthesis of microcrystalline cellulose from black tea waste (Camellia sinensis) and characterization
Int J Biol Macromol. 2023 Jun 13:125354. doi: 10.1016/j.ijbiomac.2023.125354. Online ahead of print.ABSTRACTTea wastes generated in the industries during tea production processes show excellent potential to be used as a renewable, abundant, and cheap source for the extraction of microcrystalline cellulose. In the current work, MCC was isolated from black tea waste through microwave heating instead of using conventional heating and avoiding the traditional acid hydrolysis method. Microwave increased the reaction speed significantly and resulted in very quick delignification and bleaching of black tea waste to isolate MCC in...
Source: International Journal of Biological Macromolecules - June 15, 2023 Category: Biochemistry Authors: Banhisikha Debnath Prangan Duarah Mihir Kumar Purkait Source Type: research