Form of severe malnutrition linked to DNA modification
(Baylor College of Medicine) Researchers identified significant differences at the epigenetic level -- the chemical tags in DNA that help regulate gene expression -- between two clinically distinct forms of acute childhood malnutrition known as edematous severe acute malnutrition (ESAM) and non-edematous SAM (NESAM). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 19, 2019 Category: International Medicine & Public Health Source Type: news

Are herpes virus infections linked to Alzheimer's disease?
(Baylor College of Medicine) Researchers refute the link between increased levels of herpes virus and Alzheimer's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 18, 2019 Category: International Medicine & Public Health Source Type: news

New assay assesses multiple cellular pathways at once
(Baylor College of Medicine) A novel technological approach developed by researchers at Baylor College of Medicine expands from 2 to 6 the number of molecular pathways that can be studied simultaneously in a cell sample with the dual luciferase assay, a type of testing method commonly used across biomedical fields. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 13, 2019 Category: Biology Source Type: news

New potential cancer players revealed by extensive tumor protein analysis
(Baylor College of Medicine) Analysis of all the proteins of more than 500 cancers from five different tissue sites revealed novel molecular pathways to be considered for further study regarding their potential involvement in cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 12, 2019 Category: Cancer & Oncology Source Type: news

Hyperactive FOXA1 reprograms endocrine-resistant breast cancer to become metastatic
(Baylor College of Medicine) A team led by researchers at Baylor College of Medicine and Harvard Medical School has unveiled a novel mechanism that helps explain how endocrine-resistant breast cancer acquires metastatic behavior, opening the possibility of new therapeutic strategies. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 11, 2019 Category: Cancer & Oncology Source Type: news

New bone healing mechanism has potential therapeutic applications
(Baylor College of Medicine) A new mechanism that contributes to adult bone maintenance and repair opens the possibility of developing therapeutic strategies for improving bone healing. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2019 Category: International Medicine & Public Health Source Type: news

Immune checkpoint therapy for ER+ breast cancers, a missed opportunity?
(Baylor College of Medicine) A subset of endocrine therapy-resistant luminal B breast cancers activates immune responses that could be amenable to manipulation with immunotherapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 5, 2019 Category: Cancer & Oncology Source Type: news

Scientists create 'epigenetic couch potato' mouse
(Baylor College of Medicine) A study in mice shows for the first time that epigenetics -- the molecular mechanisms that determine which genes are turned on or off -- plays a key role in determining an individual's innate drive to exercise. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 4, 2019 Category: International Medicine & Public Health Source Type: news

Big Study Finds Many Heart Procedures Won ’t Cut Risk of Having Heart Attack
This study clearly goes against what has been the common wisdom for the last 30, 40 years” and may lead to less testing and invasive treatment for such patients in the future, said Dr. Glenn Levine, a Baylor College of Medicine cardiologist with no role in the research. Some doctors still may quibble with the study, but it was very well done “and I think the results are extremely believable,” he said. About 17 million Americans have clogged arteries that crimp the heart’s blood supply, which can cause periodic chest pain. Cheap and generic aspirin, cholesterol-lowering drugs and blood pressure medic...
Source: TIME: Health - November 16, 2019 Category: Consumer Health News Authors: ARILYNN MARCHIONE / AP Tags: Uncategorized onetime Research Source Type: news

Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find
Drug therapy alone may save lives as effectively as bypass or stenting procedures, a large federal study showed. (Source: NYT Health)
Source: NYT Health - November 16, 2019 Category: Consumer Health News Authors: Gina Kolata Tags: Heart Stents (Medical Devices) Angina Drugs (Pharmaceuticals) Surgery and Surgeons Doctors American Heart Assn Baylor College of Medicine Brigham and Women ' s Hospital New York University Stanford University Source Type: news

How maternal Zika virus infection results in newborn microcephaly
(Baylor College of Medicine) Researchers have discovered that the Zika virus protein NS4A disrupts brain growth by hijacking a pathway that regulates the generation of new neurons. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 14, 2019 Category: Infectious Diseases Source Type: news

'Give me the calcium!' Tulane virus takes over cellular calcium signaling to replicate
(Baylor College of Medicine) Researchers uncover the first piece of functional evidence suggesting that Tulane virus and human norovirus use viroporins to control cellular calcium signaling. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 13, 2019 Category: International Medicine & Public Health Source Type: news

Learning to stop cancer at its roots
(Baylor College of Medicine) Leukemia stem cells initiate and sustain leukemia, but researchers have found a way to steer them toward a path of self-destruction. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 7, 2019 Category: International Medicine & Public Health Source Type: news

Disaster research planning pays off after hurricane
<div class="rxbodyfield">The first data from environmental health studies launched after&nbsp;Hurricane Harvey&nbsp;were shared at a Baylor College of Medicine symposium.</div> (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - October 2, 2019 Category: Environmental Health Source Type: news

Brain implant restores visual perception to the blind
Seven years ago, Jason Esterhuizen was in a horrific car crash that destroyed his eyes, plunging him into total darkness. Today, he ’s regained visual perception and more independence, thanks to an experimental device implanted in his brain by researchers at UCLA Health.“Now I can do things that I couldn’t do before,” said Esterhuizen, 30, who moved from his native South Africa to participate in the clinical trial at UCLA. “I can sort the laundry, find my way in lighted hallways without using a cane and cross the street more safely. It’s making my life mu ch easier.”The device is geared to people who used to...
Source: UCLA Newsroom: Health Sciences - September 18, 2019 Category: Universities & Medical Training Source Type: news