India's Biological E. to produce Johnson & Johnson's COVID-19 vaccine
Biological E., based in the southern Indian city of Hyderabad, also plans to produce 75 million to 80 million doses of its own vaccine a month from August. The drug has been developed with Baylor College of Medicine in Houston and Dynavax Technologies Corp. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 18, 2021 Category: Pharmaceuticals Source Type: news
A path to aggressive breast cancer
(Baylor College of Medicine) Following the progression of breast cancer in an animal model revealed a path that transforms a slow-growing cancer type known as estrogen receptor (ER)+/HER2+ into a fast-growing ER-/HER2+ type that aggressively spreads or metastasizes to other organs. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 17, 2021 Category: Cancer & Oncology Source Type: news
Teens Aged 12 to 15 Can Now Get Pfizer-BioNTech COVID-19 Vaccine in the U.S.
On May 10, the U.S. Food and Drug Administration (FDA) extended authorization of the Pfizer-BioNTech COVID-19 vaccine to 12- to 15-year-olds. It’s the first COVID-19 shot authorized for this younger population.
“I cannot tell you how many people have been anxiously awaiting this day to get their kids vaccinated,” says Dr. Flor Munoz, a pediatric infectious disease specialist at Texas Children’s Hospital and Baylor College of Medicine, and a member of the infectious disease committee of the American Academy of Pediatrics.
The green light was based on review of data the two companies released in March...
Source: TIME: Health - May 10, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
In a cell-eat-cell world calcium ions activate 'eat-me' signal in necrotic cells
(Baylor College of Medicine) Researchers discovered what activates the 'eat-me' signal that prompts the elimination of necrotic cells. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 6, 2021 Category: Biology Source Type: news
Fasting lowers blood pressure by reshaping the gut microbiota
(Baylor College of Medicine) For the first time researchers demonstrate that intermittent fasting can reduce hypertension by reshaping the gut microbiota in an animal model. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 29, 2021 Category: International Medicine & Public Health Source Type: news
Sperm development linked to testicular cancer
(The Company of Biologists) Scientists led by Dr Jason Heaney from Baylor College of Medicine in Texas, USA, have found that a failure in the development of sperm cells can lead to the formation of testicular tumours in mice. These findings, published in the journal Development, provide new clues for understanding how testicular cancer arises in mammals. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 28, 2021 Category: Cancer & Oncology Source Type: news
Bone microenvironment fosters breast cancer metastatic behavior
(Baylor College of Medicine) The bone microenvironment reduced ER expression in ER+ breast cancer cells and triggered reprogramming that promoted the cancer cells' ability to metastasize. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 19, 2021 Category: Cancer & Oncology Source Type: news
POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner
(Baylor College of Medicine) Researchers have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 19, 2021 Category: International Medicine & Public Health Source Type: news
Closer to human -- Mouse model more accurately reproduces fatty liver disease
(Baylor College of Medicine) Researchers have developed a novel mouse model that reproduces many key features of human non-alcoholic fatty liver disease (NAFLD), a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 13, 2021 Category: Cancer & Oncology Source Type: news
Novel guidelines help select optimal deconvolution method
(Baylor College of Medicine) Selecting the right deconvolution method to analyze the composition of complex mixtures of cells just got easier. Researchers at Baylor College of Medicine derived clear guidelines scientists can use to determine the deconvolution method that optimally fits their needs. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 13, 2021 Category: Biology Source Type: news
Phase III Trial of Durvalumab for Mesothelioma Underway
The U.S. Food and Drug Administration will be closely watching the latest, international phase III clinical trial for unresectable pleural mesothelioma involving the immunotherapy drug durvalumab.
FDA approval may be coming soon.
“It looks very promising,” Dr. Arkadiusz Dudek, of Regions Hospital Cancer Care Center in St. Paul, Minnesota, told The Mesothelioma Center at Asbestos.com. “The hope is to have the regimen approved by the FDA as front-line therapy. There is a real need today for more options with mesothelioma.”
The goal of the randomized trial – officially known as DREAM3R – is to determine h...
Source: Asbestos and Mesothelioma News - April 1, 2021 Category: Environmental Health Authors: Fran Mannino Source Type: news
GlyNAC improves multiple defects in aging to boost strength and cognition in older humans
(Baylor College of Medicine) GlyNAC - a combination precursors of the natural antioxidant glutathione - improved many age-associated defects in older humans boosting muscle strength and cognition. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 29, 2021 Category: International Medicine & Public Health Source Type: news
Correcting altered brain circuit could tackle coinciding obesity and depression
(Baylor College of Medicine) Researchers have identified and characterized a novel neural circuit that mediates the reciprocal control of obesity and depression in mouse models, and a potential therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 26, 2021 Category: International Medicine & Public Health Source Type: news
Circadian clock gene Rev-erb linked to dawn phenomenon in type 2 diabetes
(Baylor College of Medicine) Researchers found that mice lacking the circadian clock gene called Rev-erb in the brain show characteristics similar to those of human dawn phenomenon in type2 diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 25, 2021 Category: International Medicine & Public Health Source Type: news
Study reveals how long-term infection and inflammation impairs immune response as we age
(Texas Children's Hospital) A study published led by Dr. Katherine King, associate professor at Baylor College of Medicine and Texas Children's Hospital, shows for the first time that long-term infection and chronic inflammation drive CH mediated by the loss of Dnmt3a function. In addition, the study offers key insights into the mechanism by which chronic inflammation leads to CH and demonstrates the critical role of DNMT3a in regulating normal HSC responses to infections. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 25, 2021 Category: International Medicine & Public Health Source Type: news
