Optogenetic method can reveal how gut microbes affect longevity
(Baylor College of Medicine) Optogenetics offers a direct way to manipulate gut bacterial metabolism in a temporally, quantitatively and spatially controlled manner and enhance host fitness. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 17, 2020 Category: Biology Source Type: news

Maternal diet during lactation shapes functional abilities of milk bacteria
(Baylor College of Medicine) The mother's diet while breastfeeding can shape the profile of human milk oligosaccharides (HMO), a type of complex carbohydrate in the mother's milk. Changing the HMOs, which are food and fodder for healthy microbes, in turn modifies the functional abilities of the milk microbiome. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 16, 2020 Category: International Medicine & Public Health Source Type: news

Novel gene variants that modify the risk of late-onset Alzheimer's disease discovered
(Baylor College of Medicine) Researchers at Baylor College of Medicine and Texas Children's Hospital have identified 216 new genetic modifiers of late-onset Alzheimer's disease. The newly-identified biomarkers could potentially be used in the future to refine risk assessment, patient prognosis and act as therapeutic targets for this untreatable condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 8, 2020 Category: International Medicine & Public Health Source Type: news

A role for the slow oscillations of the neocortex in epileptic spasm generation
(Baylor College of Medicine) Epileptic spasms are a type of brief seizures that are the hallmark of catastrophic seizure disorders and characterized by severe cognitive and motor deficits. Researchers from Baylor College of Medicine and Texas Children's Hospital have found the source and mechanism to explain how cortical neurons generate spasms. This is also the first study to reveal a hitherto unknown relationship between a normal brain state, like sleep, and spasms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 8, 2020 Category: International Medicine & Public Health Source Type: news

The tree of cortical cell types describes the diversity of neurons in the brain
(Baylor College of Medicine) The tree of cortical cell types provides one of the most detailed and complete characterizations of the diversity of neural types in the brain so far. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 2, 2020 Category: International Medicine & Public Health Source Type: news

The future of health care: Experts discuss health care, real estate in a post-COVID world (live webinar recap)
On Tuesday, Nov. 10, 2020, HBJ President and Publisher Bob Charlet sat down, virtually, with our panel of experts to address how the current public health crisis is changing our outlook on business, medicine and the economy and how health systems and companies across the country are reassessing their real estate portfolios as they prepare for a post-COVID-19 environment. Panelist: Dr. Doug Lawson, CEO, St. Luke’s Health; Dr. Paul Klotman, president and CEO, Baylor College of Medicine; Becky… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 1, 2020 Category: Biotechnology Source Type: news

Gloria Echeverria Investigates an Insidious Form of Breast Cancer
The newly minted Baylor College of Medicine faculty member is working to crack the mystery of triple negative breast cancer. (Source: The Scientist)
Source: The Scientist - December 1, 2020 Category: Science Tags: Scientist to Watch Source Type: news

Treatment shows reduction in heart failure after myocardial infarction
(Baylor College of Medicine) Researchers at Baylor College of Medicine identified potential preventative therapies for heart failure after a significant heart attack. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 24, 2020 Category: International Medicine & Public Health Source Type: news

BICRA gene provides answers to patients, doctors and scientists
(Baylor College of Medicine) Researchers identified the BICRA gene as a new disease gene involved in a neurodevelopmental disorder and found evidence that BICRA functions in neural development in humans and flies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 23, 2020 Category: International Medicine & Public Health Source Type: news

Predicting preterm births
(Baylor College of Medicine) Researchers studied how family history can predict preterm birth. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2020 Category: International Medicine & Public Health Source Type: news

How rotavirus causes severe gastrointestinal disease
(Baylor College of Medicine) Using intercellular calcium waves, rotavirus amplifies its ability to cause disease beyond the cells it directly infects. This is the first virus identified to activate ADP-mediated intercellular calcium waves. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2020 Category: International Medicine & Public Health Source Type: news

Maraxilibat reduces debilitating itching in children with Alagille syndrome
(Baylor College of Medicine) On behalf of Childhood Liver Disease Research Network (ChiLDReN), Texas Children's Hospital and Baylor College of Medicine researchers report that prolonged treatment with Maraxilibat resulted in clinically meaningful improvements in debilitating itching (pruritus) and related quality of life outcomes in children with Alagille syndrome. The novel pharmacological approach addresses a major unfulfilled therapeutic need to control severe and relentless itching in pediatric patients with Alagille syndrome. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2020 Category: International Medicine & Public Health Source Type: news

Proteogenomics enhances the identification of therapeutic vulnerabilities in breast cancer
(Baylor College of Medicine) Applying powerful proteogenomics approaches to breast cancer, researchers propose more precise diagnostics, identify new tumor susceptibilities for translation into treatments and implicate new mechanisms involved in breast cancer treatment resistance. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2020 Category: International Medicine & Public Health Source Type: news

Revealing the unexpected structure of iron-exporter ferroportin
(Baylor College of Medicine) The 3D structure of a mammalian ferroportin reveals unexpected characteristics and a mode of action that could lead to innovative therapies. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 17, 2020 Category: Biology Source Type: news

Biological E gets DGCA nod to begin the next phase of trials for its COVID-19 vaccine
This vaccine candidate includes an antigen that was in-licensed from BCM Ventures, which is an integrated commercialisation team of Baylor College of Medicine in Houston, and an advanced adjuvant from the US-based vaccine focused pharmaceutical firm Dynavax Technologies Corporation. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 17, 2020 Category: Pharmaceuticals Source Type: news