Early training delays symptom onset in mouse model of Rett syndrome
(Baylor College of Medicine) Researchers found that in a mouse model of Rett syndrome, intensive training beginning before symptoms appear dramatically improved the performance of specific motor and memory tasks and substantially delayed the appearance of symptoms. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - March 24, 2021 Category: International Medicine & Public Health Source Type: news

Identifying rare genetic variants that increase risk for lung cancer
(Baylor College of Medicine) New research led by Baylor College of Medicine identified 25 new rare pathogenic variants associated with lung cancer susceptibility and validated five of those variants. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 18, 2021 Category: Cancer & Oncology Source Type: news

Researchers identify DNA elements that affect MECP2 expression
(Baylor College of Medicine) Researchers have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 18, 2021 Category: International Medicine & Public Health Source Type: news

Proteomics analysis identifies potential drug targets for aggressive human cancers
(Baylor College of Medicine) Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 4, 2021 Category: Cancer & Oncology Source Type: news

Deep brain stimulation and exercise restore movement in ataxia
(Baylor College of Medicine) New research from Baylor College of Medicine scientists shows that a combination of deep brain stimulation (DBS) and exercise has potential benefits for treating ataxia, a rare genetic neurodegenerative disease characterized by progressive irreversible problems with movement. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 26, 2021 Category: International Medicine & Public Health Source Type: news

Study: Which Mesothelioma Patients Will Immunotherapy Benefit?
This study also is designed to better understand the biological mechanisms affecting the immune system. The goal is to use both the cellular organization and molecular pathways to develop a test that can predict the response to the checkpoint inhibitor drugs. Upon completion, a clinical trial would follow, in which treatment would depend on the results of the individual’s test. “Within the next year or two, we’ll have a good idea of whether these components are working,” Burt said. The post Study: Which Mesothelioma Patients Will Immunotherapy Benefit? appeared first on Mesothelioma Center - Vital S...
Source: Asbestos and Mesothelioma News - February 23, 2021 Category: Environmental Health Authors: Amy Edel Source Type: news

Targeting MAPK4 emerges as a promising therapy for prostate cancer
(Baylor College of Medicine) New research opens the possibility that targeting the enzyme MAPK4 in human prostate cancer might provide a novel therapeutic strategy for this disease that is the second leading cause of cancer death in American men. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 19, 2021 Category: Cancer & Oncology Source Type: news

Study seeks to identify biological markers that predict mesothelioma response to treatment
(Baylor College of Medicine) The goal of this study is to develop a clinically relevant test that would enable physicians to determine whether a patient would be most likely or less likely to respond to a form of immunotherapy before the patient gets treatment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 16, 2021 Category: Cancer & Oncology Source Type: news

SRC-3 is a novel regulator of human immune T regulatory cells
(Baylor College of Medicine) SRC-3, a prognostic marker for aggressive human breast and other cancers, also regulates human immune T regulatory cells (Tregs), which are involved in fighting cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 11, 2021 Category: International Medicine & Public Health Source Type: news

Phages can anticipate bacteria's location and destroy them before they cause an infection
(Baylor College of Medicine) A novel strategy has the potential of becoming a game changer in the fight against antibiotic-resistant bacteria that live in hard-to-reach places. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 9, 2021 Category: International Medicine & Public Health Source Type: news

VA ’s ‘Million Veterans Program’ Research Study Receives Its 100,000th Human Genome Sequence
With improved genetic sequencing comes larger human genome databases that could lead to new diagnostic and therapeutic biomarkers for clinical laboratories As the COVID-19 pandemic grabbed headlines, the human genome database at the US Department of Veterans Affairs Million Veterans Program (MVP) quietly grew. Now, this wealth of genomic information—as well as data from other […] The post VA’s ‘Million Veterans Program’ Research Study Receives Its 100,000th Human Genome Sequence appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - February 5, 2021 Category: Laboratory Medicine Authors: Jude Tags: Laboratory Management and Operations Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations Precision Medicine All of Us anatomic pathology Baylor College of Medicine biomarkers Brad Oze Source Type: news

Duration of antibody response varies among adults naturally reinfected with RSV
(Baylor College of Medicine) Researchers at Baylor College of Medicine found that while most individuals responded to respiratory syncytial virus (RSV) natural reinfection with a typical sustained antibody response associated with protection, a few individuals surprisingly responded atypically, not being able to sustain the antibody response, which declined to levels that made the individuals susceptible to RSV reinfection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 4, 2021 Category: Infectious Diseases Source Type: news

3-D printed Biomesh minimizes hernia repair complications
(Baylor College of Medicine) A newly-designed 3D-printed Biomesh effectively minimized postsurgical complications of hernia repair in an animal model. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 25, 2021 Category: International Medicine & Public Health Source Type: news

The U.S. Fumbled Its Early Vaccine Rollout. Will the Biden Administration Put America Back on Track?
On a frigid morning in January, Trudy Ronnel settled into her favorite sofa chair at the Westminster Place senior-living community in Evanston, Ill., pulled down the neckline on her red blouse and braced herself for a shot she’d anticipated for almost a year. At 92 years old, with multiple medical conditions, she spent most of 2020 fearful of contracting the COVID-19 plague that ravaged the world outside her first-floor window. To protect herself, for the past few months she’d avoided Westminster’s communal rooms, which had provided a means to stay active and engaged but risked becoming a pathogenic petri...
Source: TIME: Health - January 21, 2021 Category: Consumer Health News Authors: W.J. Hennigan, Alice Park and Jamie Ducharme Tags: Uncategorized COVID-19 feature Magazine Source Type: news

Triggering tumor antiviral immune response in triple negative breast cancer
(Baylor College of Medicine) Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 14, 2021 Category: Cancer & Oncology Source Type: news