A novel neurological disorder associated with the Polycomb complex identified
(Texas Children's Hospital) A multi-institutional study has discovered spontaneous mutations in RNF2 (RING2) gene as the underlying cause of a novel neurological disorder. This Undiagnosed Diseases Network (UDN) study was led by Dr. Shinya Yamamoto, investigator at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children's Hospital and assistant professor at Baylor College of Medicine, and Dr. Vandana Shashi at Duke University Medical Center. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 8, 2021 Category: International Medicine & Public Health Source Type: news

University of Utah and Sloan Kettering Institute Study Sheds Light on How the Body Recognizes “Good” from Bad Bacteria in the Microbiome
Researchers found that early in life intestinal microorganisms “educate” the thymus to develop T cells; findings could lead to improved immune system therapeutics and associated clinical laboratory tests Researchers at the University of Utah and the Sloan Kettering Institute (SKI)—the experimental research division of the Memorial Sloan Kettering Cancer Center (MSKCC) in New York—have uncovered […] The post University of Utah and Sloan Kettering Institute Study Sheds Light on How the Body Recognizes “Good” from Bad Bacteria in the Microbiome appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - June 30, 2021 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Laboratory Pathology Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine anatomic pathology Baylor College of Medicine clinical laboratory clinical pathology commensal microorganisms Dark D Source Type: news

A promising two-punch therapy for Langerhans cell histiocytosis
(Baylor College of Medicine) A novel combination therapy resulted in a significant decrease of disease burden in an animal model of LCH. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 29, 2021 Category: Cancer & Oncology Source Type: news

Baylor St. Luke ’s Medical Center celebrates new O’Quinn Medical Tower topping out
The joint venture between Baylor College of Medicine and St. Luke ’s Health held a topping out ceremony for the new 12-story tower on June 24. The tower is expected to be complete in 2023. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - June 25, 2021 Category: American Health Authors: Olivia Pulsinelli Source Type: news

Mental Health in the Workplace: How the pandemic impacted employees, and what employers should know
Armando Colombo, President& CEO, The Menninger Clinic Kara Hill, MHA, Director of Integrated Health Care Initiative, Mental Health America of Greater Houston Benji T. Kurian, M.D., MPH, Executive Medical Director for the Risk Identification& Outreach (RIO) program, Blue Cross and Blue Shield of Texas Nidal Moukaddam, M.D., PhD, Department of Psychiatry, Harris Health System, Associate Professor, Psychiatry& Behavioral Services, Baylor College of Medicine Bob Charlet, President& Publisher, … (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - June 25, 2021 Category: American Health Source Type: news

'Genomics of Rare Diseases. Understanding Disease Genetics Using Genomic Approaches'
(Baylor College of Medicine) " Genomics of Rare Diseases " offers readers a broad understanding of current knowledge on rare diseases from a genomics perspective. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 25, 2021 Category: International Medicine & Public Health Source Type: news

Glial cells help mitigate neurological damage in Huntington's disease
(Baylor College of Medicine) Glia affected by Huntington's disease respond by tuning down synapse genes, which has a protective effect. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 24, 2021 Category: International Medicine & Public Health Source Type: news

Drug doubles down on bone cancer, metastasis
Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it. Chemist Han Xiao at Rice and biologist Xiang Zhang at Baylor and their labs have developed an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis. (Source: World Pharma News)
Source: World Pharma News - June 23, 2021 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Drug doubles down on bone cancer, metastasis
(Rice University) Researchers at Rice University and Baylor College of Medicine develop an antibody conjugate called BonTarg that delivers drugs to bone tumors and inhibits metastasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 23, 2021 Category: Cancer & Oncology Source Type: news

Rap1 controls the body's sugar levels from the brain
(Baylor College of Medicine) Researchers have discovered a mechanism in a small area of the brain that regulates whole-body glucose balance without affecting body weight. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 22, 2021 Category: International Medicine & Public Health Source Type: news

Most comprehensive RNA-Atlas ever
(Ghent University) By cleverly combining complementary sequencing techniques, researchers of Ghent University, together with Baylor College of Medicine and the world's leading sequencing company, Illumina, have deepened our understanding of the function of known RNA molecules and discovered thousands of new RNAs. A better understanding of our transcriptome is essential to better understand disease processes and uncover novel genes that may serve as therapeutic targets or biomarkers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 17, 2021 Category: International Medicine & Public Health Source Type: news

Understanding the cause of joint and tendon dysfunction in osteogenesis imperfecta
(Baylor College of Medicine) Researchers at Baylor College of Medicine have identified a protein signaling mechanism driving join dysfunction in OI and find that inhibiting this signaling pathway can prevent onset of tendinopathy problems in mouse models. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 14, 2021 Category: International Medicine & Public Health Source Type: news

Reference genome comparison finds exome variant discrepancies in 206 genes
(Baylor College of Medicine) Researchers at the Human Genome Sequencing Center at Baylor College of Medicine have identified genetic variant discrepancies between the hg19 and hg28 reference genomes, creating guidance for laboratories to take advantage of an improved human reference genome. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 14, 2021 Category: Biology Source Type: news

What We Learned About Genetic Sequencing During COVID-19 Could Revolutionize Public Health
You don’t want to be a virus in Dr. David Ho’s lab. Pretty much every day since the COVID-19 pandemic began, Ho and his team have done nothing but find ways to stress SARS-CoV-2, the virus that causes the disease. His goal: pressure the virus relentlessly enough that it mutates to survive, so drug developers can understand how the virus might respond to new treatments. As a virologist with decades of experience learning about another obstinate virus, HIV, Ho knows just how to apply that mutation-generating stress, whether by starving the virus, bathing it in antibodies that disrupt its ability to infect cells, ...
Source: TIME: Health - June 11, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 feature Genetics Magazine Source Type: news

This brain circuit signals when to stop eating; could regulating it help with obesity
(Baylor College of Medicine) At Baylor College of Medicine, Dr. Qi Wu, Dr. Yong Han and their colleagues have uncovered new aspects of little-known neural circuits and neurotransmitters involved in ending food consumption. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 26, 2021 Category: International Medicine & Public Health Source Type: news