What We Learned About Genetic Sequencing During COVID-19 Could Revolutionize Public Health

You don’t want to be a virus in Dr. David Ho’s lab. Pretty much every day since the COVID-19 pandemic began, Ho and his team have done nothing but find ways to stress SARS-CoV-2, the virus that causes the disease. His goal: pressure the virus relentlessly enough that it mutates to survive, so drug developers can understand how the virus might respond to new treatments. As a virologist with decades of experience learning about another obstinate virus, HIV, Ho knows just how to apply that mutation-generating stress, whether by starving the virus, bathing it in antibodies that disrupt its ability to infect cells, or bombarding it with enough promising antiviral drug candidates to make it blink. “We actually have more mutants [of SARS-CoV-2] selected in the lab than I suspect most labs do,” says Ho. “We just need the will and leadership and especially the public to demand that the devastation of COVID-19 is something that shouldn’t have happened and that we never want to have happen again.” “Viruses mutate. It’s what they do.” [time-brightcove not-tgx=”true”] As a result of that work, “we have basically been seeing viral evolution happen in front of our eyes for the past year and a half,” he says. Ho, director of the Aaron Diamond AIDS Research Center at Columbia University, is among the vanguard of researchers aggressively finding ways to dismantle SARS-CoV-2 from the inside out—by mining t...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 feature Genetics Magazine Source Type: news

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Conclusion: This article outlines the evaluation of a new program demonstrating that medical oncology practices can make improvements in the care of their underserved populations if provided with the proper tools, methods, and coaching. The use of formative evaluation methodology also identified opportunities for improvement and ultimately resulted in additional funding for more practices to participate in the program.
Source: Quality Management in Healthcare - Category: Health Management Tags: Methods and Instruments Source Type: research
Health care systems have encountered unprecedented challenges during the coronavirus disease-2019 (COVID-19) pandemic, such as standardizing care in the absence of high-quality data. As an emblematic example, preliminary data and early anecdotal experience suggested that a major driver of COVID-19 pathophysiology was hypercoagulability, suggesting the need for aggressive anticoagulation. In this article, we describe the rapid guidance process for the development of an anticoagulation protocol for COVID-19. Preliminary evidence was collected from multidisciplinary experts within our institution to inform the first protocol ...
Source: Quality Management in Healthcare - Category: Health Management Tags: Commentary Source Type: research
ConclusionWe showed distinct patterns of diffuse brain SWI susceptibilities in critically-ill patients who underwent mechanical ventilation/ECMO. The etiology of these foci remains uncertain, but the association with mechanical ventilation, prolonged respiratory failure, and hypoxemia seems probable explanations.
Source: Neuroradiology - Category: Radiology Source Type: research
Abstract: Human papillomavirus (HPV) is a leading cause of cancer. Increasing HPV vaccination recommendations by primary care providers to patients decreases the burden of this viral infection. Providers need to be educated about this condition and the available options for immunization to feel confident in making strong recommendations and thereby increase HPV immunization rates.
Source: The Nurse Practitioner - Category: Nursing Tags: Feature Source Type: research
No abstract available
Source: The Nurse Practitioner - Category: Nursing Tags: Department: Preventing, Treating, and Surviving Cancer Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
AbstractThe COVID-19 pandemic has called for and generated massive novel government regulations to increase social distancing for the purpose of reducing disease transmission. A number of studies have attempted to guide and measure the effectiveness of these policies, but there has been less focus on the overall efficiency of these policies. Efficient social distancing requires implementing stricter restrictions during periods of high viral prevalence and rationing social contact to disproportionately preserve gatherings that produce a good ratio of benefits to transmission risk. To evaluate whether U.S. social distancing ...
Source: Risk Analysis - Category: International Medicine & Public Health Authors: Tags: Original Research Article Source Type: research
A federal appeals court has issued a temporary injunction against a Covid-19 vaccine mandate for New York City educators set to go into...
Source: Reuters: Health - Category: Consumer Health News Source Type: news
New York City schools have been temporarily blocked from enforcing a vaccine mandate for its teachers and other workers by a federal appeals judge days before it was to take effect
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Alaska, where ICU hospitalizations rose 14%, has the highest rate of Covid-19 cases by far.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Tags: Healthcare /healthcare Innovation /innovation Breaking breaking-news Coronavirus Source Type: news
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