1019 Multi-country trial of intrapartum oral azithromycin: cultures of maternal infections
An intrapartum oral dose of azithromycin (AZI) reduced maternal death or sepsis (by WHO clinical criteria). Herein, we compare the frequency of cultures, organisms and antimicrobial resistance from maternal infections by AZI vs. placebo groups. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - January 1, 2024 Category: OBGYN Authors: Alan T. Tita Source Type: research

Vibrio species: development of EUCAST susceptibility testing methods and MIC and zone diameter distributions on which to determine clinical breakpoints
ConclusionsWe demonstrated the validity of using standard BMD and EUCAST disc diffusion methodology for AST of fiveVibrio spp., and generated suitable data to allow EUCAST to determine clinical MIC and zone diameter breakpoints for five pathogenicVibrio spp., including both non-toxigenic and toxigenicV. cholerae. (Source: Journal of Antimicrobial Chemotherapy)
Source: Journal of Antimicrobial Chemotherapy - December 30, 2023 Category: Microbiology Source Type: research

Effects of azithromycin exposure during pregnancy at different stages, doses and courses on testicular development in fetal mice
Biomed Pharmacother. 2023 Dec 27;170:116063. doi: 10.1016/j.biopha.2023.116063. Online ahead of print.ABSTRACTAzithromycin is a commonly used antibiotic during pregnancy, but some studies have suggested its potential developmental toxicity. Currently, the effects and mechanisms of prenatal azithromycin exposure (PAzE) on fetal testicular development are still unclear. The effects of prenatal exposure to the same drug on fetal testicular development could vary depending on different stages, doses, and courses. Hence, in this study, based on clinical medication characteristics, Kunming mice was administered intragastrically ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 28, 2023 Category: Drugs & Pharmacology Authors: Ziyu Kong Lu Zhu Yi Liu Yi Liu Guanghui Chen Tao Jiang Hui Wang Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Effects of azithromycin exposure during pregnancy at different stages, doses and courses on testicular development in fetal mice
Biomed Pharmacother. 2023 Dec 27;170:116063. doi: 10.1016/j.biopha.2023.116063. Online ahead of print.ABSTRACTAzithromycin is a commonly used antibiotic during pregnancy, but some studies have suggested its potential developmental toxicity. Currently, the effects and mechanisms of prenatal azithromycin exposure (PAzE) on fetal testicular development are still unclear. The effects of prenatal exposure to the same drug on fetal testicular development could vary depending on different stages, doses, and courses. Hence, in this study, based on clinical medication characteristics, Kunming mice was administered intragastrically ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 28, 2023 Category: Drugs & Pharmacology Authors: Ziyu Kong Lu Zhu Yi Liu Yi Liu Guanghui Chen Tao Jiang Hui Wang Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Effects of azithromycin exposure during pregnancy at different stages, doses and courses on testicular development in fetal mice
Biomed Pharmacother. 2023 Dec 27;170:116063. doi: 10.1016/j.biopha.2023.116063. Online ahead of print.ABSTRACTAzithromycin is a commonly used antibiotic during pregnancy, but some studies have suggested its potential developmental toxicity. Currently, the effects and mechanisms of prenatal azithromycin exposure (PAzE) on fetal testicular development are still unclear. The effects of prenatal exposure to the same drug on fetal testicular development could vary depending on different stages, doses, and courses. Hence, in this study, based on clinical medication characteristics, Kunming mice was administered intragastrically ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 28, 2023 Category: Drugs & Pharmacology Authors: Ziyu Kong Lu Zhu Yi Liu Yi Liu Guanghui Chen Tao Jiang Hui Wang Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Effects of azithromycin exposure during pregnancy at different stages, doses and courses on testicular development in fetal mice
Biomed Pharmacother. 2023 Dec 27;170:116063. doi: 10.1016/j.biopha.2023.116063. Online ahead of print.ABSTRACTAzithromycin is a commonly used antibiotic during pregnancy, but some studies have suggested its potential developmental toxicity. Currently, the effects and mechanisms of prenatal azithromycin exposure (PAzE) on fetal testicular development are still unclear. The effects of prenatal exposure to the same drug on fetal testicular development could vary depending on different stages, doses, and courses. Hence, in this study, based on clinical medication characteristics, Kunming mice was administered intragastrically ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 28, 2023 Category: Drugs & Pharmacology Authors: Ziyu Kong Lu Zhu Yi Liu Yi Liu Guanghui Chen Tao Jiang Hui Wang Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Effects of azithromycin exposure during pregnancy at different stages, doses and courses on testicular development in fetal mice
Biomed Pharmacother. 2023 Dec 27;170:116063. doi: 10.1016/j.biopha.2023.116063. Online ahead of print.ABSTRACTAzithromycin is a commonly used antibiotic during pregnancy, but some studies have suggested its potential developmental toxicity. Currently, the effects and mechanisms of prenatal azithromycin exposure (PAzE) on fetal testicular development are still unclear. The effects of prenatal exposure to the same drug on fetal testicular development could vary depending on different stages, doses, and courses. Hence, in this study, based on clinical medication characteristics, Kunming mice was administered intragastrically ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 28, 2023 Category: Drugs & Pharmacology Authors: Ziyu Kong Lu Zhu Yi Liu Yi Liu Guanghui Chen Tao Jiang Hui Wang Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research

Antibiotic sensitivity of environmental Legionella pneumophila strains isolated in Poland
CONCLUSIONS: The lowest biocidal concentration was found for levofloxacin, the highest for tetracycline. The highest MIC50 and MIC90 values were found for tetracycline and the lowest for rifampicin. The highest biocidal values were found for azithromycin and the lowest for tetracycline.PMID:38153060 | DOI:10.26444/aaem/167934 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - December 28, 2023 Category: Environmental Health Authors: Iwona G ładysz Agnieszka Sikora Ma łgorzata Wójtowicz-Bobin Adam Szepeluk Renata Matuszewska Marta Bartosik Jan Kazimierz Karczewski Source Type: research