UIC to lead national COPD clinical trial
(University of Illinois at Chicago) The University of Illinois at Chicago will lead a $14.6 million, multi-center research project to determine which of two drugs -- azithromycin, an antibiotic, or roflumilast, an anti-inflammatory medication -- is the most effective at treating chronic obstructive pulmonary disease, which is also known as COPD. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 9, 2019 Category: International Medicine & Public Health Source Type: news

Doxycycline vs. Azithromycin
Title: Doxycycline vs. AzithromycinCategory: MedicationsCreated: 5/7/2019 12:00:00 AMLast Editorial Review: 5/7/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - May 7, 2019 Category: Drugs & Pharmacology Source Type: news

New drug combination could be effective for treatment-resistant gonorrhoea
Gentamicin with azithromycin was found to be almost as effective as the currently used first-line treatment for gonorrhoea Related items fromOnMedica Promise to end new HIV transmissions in England by 2030 Use condoms to cut spread of drug-resistant gonorrhoea HPV programme linked to dramatic fall in cervical disease Uptake of PrEP coincides with less condom use Gonorrhoea becoming difficult or impossible to treat, warns WHO (Source: OnMedica Latest News)
Source: OnMedica Latest News - May 7, 2019 Category: UK Health Source Type: news

Azithromycin May Reduce Treatment Failure for COPD Exacerbations Azithromycin May Reduce Treatment Failure for COPD Exacerbations
An extended course of low-dose azithromycin may significantly reduce treatment failure in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (COPD), new data suggest.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - May 6, 2019 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

Azithromycin May Reduce Treatment Failure for COPD
Exacerbations (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 6, 2019 Category: General Medicine Source Type: news

Impact of Azithromycin Studied in Acute Exacerbation of COPD
Azithromycin leads to significant drops in treatment intensification and step - up in hospital care (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - May 3, 2019 Category: Respiratory Medicine Tags: Internal Medicine, Critical Care, Pharmacy, Pulmonology, Journal, Source Type: news

Impact of Azithromycin Studied in Acute Exacerbation of COPD
FRIDAY, May 3, 2019 -- Three months of azithromycin did not significantly reduce treatment failure (TF) among patients hospitalized for an acute exacerbation of chronic obstructive pulmonary disease (AECOPD), according to a study published online... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 3, 2019 Category: Pharmaceuticals Source Type: news

Azithromycin appears to reduce treatment failure in severe, acute COPD exacerbations
(American Thoracic Society) The antibiotic azithromycin may reduce treatment failure in patients hospitalized for an acute exacerbation of chronic obstructive pulmonary disease (COPD), according to a randomized, controlled trial published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 3, 2019 Category: International Medicine & Public Health Source Type: news

Drug combination could be effective for treatment-resistant gonorrhea
(National Institute for Health Research) Scientists comparing treatments for gonorrhea have identified a drug combination that could be an effective back-up for patients not responding to current therapy. The research team, from University Hospitals Birmingham, found that a treatment of the antibiotic gentamicin with azithromycin worked almost as well as the currently used ceftriaxone for genital gonorrhea. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 2, 2019 Category: Infectious Diseases Source Type: news

Gonorrhoea: Drug resistance compromises recommended treatment in Europe
(European Centre for Disease Prevention and Control (ECDC)) Gonorrhoea is the second most commonly notified sexually transmitted infection across the EU/EEA countries with almost 500 000 reported cases between 2007 and 2016. The infection is treatable but Neisseria gonorrhoeae keep showing high levels of azithromycin resistance according to latest results of the European Gonococcal Antimicrobial Surveillance Programme. This antibiotic agent is part of the currently recommended therapy regimen for gonorrhoea and observed resistance patterns threaten its effectiveness. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 28, 2019 Category: Infectious Diseases Source Type: news

Antibiotics for treating urogenital Chlamydia trachomatis infection in men and nonpregnant women
This review of 14 RCTs (n=2715) concludes in men, regimens with azithromycin are less effective than doxycycline for microbiological failure, but no difference for clinical failure; in women, it is uncertain whether azithromycin vs doxycycline increases risk of microbiological failure (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 27, 2019 Category: Consumer Health News Source Type: news

Azasite (Azithromycin Ophthalmic Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Several antibiotics appear effective against early-stage Lyme disease
This meta-analysis suggests that when symptoms of the disease are confined to a localised skin infection, treatment failures are relatively infrequent, only 2% at 12 months. Effective antibiotics include penicillin V, doxycycline, azithromycin, cefuroxime, amoxicillin and ceftriaxone plus doxycycline.The research has significant limitations, but choice, dose and duration of antibiotics appear to have little impact on outcomes. This research does not suggest that guidelines need to be reviewed. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 15, 2019 Category: Consumer Health News Source Type: news

Malaria Tx Plus Azithromycin Fails to Cut Deaths, Hospital Time (CME/CE)
(MedPage Today) -- African kids taking azithromycin had less frequent rates of GI infections and more (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - February 4, 2019 Category: American Health Source Type: news

Azithromycin Add-On Fails to Cut Malaria Deaths, Hospital Stays
(MedPage Today) -- But less frequent infections seen in African kids who received the antibiotic (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - January 30, 2019 Category: American Health Source Type: news

My High-risk Flu Patients Get Antibiotics, and Here ’s Why
Of course they get oseltamivir--but our author has been adding azithromycin for his high-risk patients since the 2015-16 season. He explains why. (Source: ConsultantLive)
Source: ConsultantLive - January 23, 2019 Category: Internal Medicine Authors: C. Andrew Schroeder, MD Tags: Respiratory Diseases Source Type: news

Featured Review: Adverse events in people taking macrolide antibiotics versus placebo for any indication
The review 'Adverse events in people taking macrolide antibiotics'   asked, “Will people taking a macrolide antibiotic experience more adverse events than those treated with placebo?”Macrolide antibiotics are one of many types of antibiotic. They are commonly used to treat both acute and chronic infections. The four most commonly used macrolides are azithromycin, clarithromycin, erythromycin, and roxithromycin. People taking macrolide antibiotics are at risk of experiencing adverse events such as nausea, diarrhoea or rashes.Lead author of the review Malene Plejdrup Hansen explains, “This review was u...
Source: Cochrane News and Events - December 17, 2018 Category: Information Technology Authors: Katie Abbotts Source Type: news

Antibiotics could extend your life by culling older cells that can no longer divide
Salford University scientists made the discovery using azithromycin, which treats infections ranging from gonorrhoea to Lyme disease. (Source: the Mail online | Health)
Source: the Mail online | Health - November 27, 2018 Category: Consumer Health News Source Type: news

Aurobindo Pharma gets USFDA nod for infections treatment drug
The company has received final approval from the US Food and Drug Administration (USFDA) to manufacture and market Azithromycin Oral suspension 100 mg /5 mL and 200 mg/5 mL. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - October 11, 2018 Category: Pharmaceuticals Source Type: news

Azithromycin (Azasite) Ophthalmic Solution 1% (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 4, 2018 Category: Drugs & Pharmacology Source Type: news

Amoxicillin-Clavulanate Remains Top Choice for Bronchiectasis Exacerbations in Kids Amoxicillin-Clavulanate Remains Top Choice for Bronchiectasis Exacerbations in Kids
Although azithromycin is noninferior to amoxicillin-clavulanate for resolving bronchiectasis exacerbations in children, the shorter time to resolution with amoxicillin-clavulanate makes it the better choice for first-line empirical antibiotic treatment, according to results from the BEST-2 trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 28, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Subbing Azithromycin for Augmentin Flops in Pediatric Bronchiectasis
(MedPage Today) -- But macrolide is option for penicillin-hypersensitive kids (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - September 19, 2018 Category: Infectious Diseases Source Type: news

Drug-resistance of gonorrhea in the EU: persistent but stable
(European Centre for Disease Prevention and Control (ECDC)) Neisseria gonorrhoea continues to show high levels of resistance to azithromycin across the European Union and European Economic Area, according to the 2016 results of the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP). This threatens the effectiveness of the currently recommended dual therapy regimen for gonorrhea. Overall, the rates of resistance to cefixime, ceftriaxone and azithromycin have remained stable when compared to recent years. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 30, 2018 Category: Infectious Diseases Source Type: news

Zimbabwe:Drug Resistant Typhoid Is Real
[The Herald] This strain of typhoid is not responding to traditionally used medicines such as ciprofloxacin and health workers have resorted to using the last line of antibiotics, azithromycin in defence against typhoid while waiting for approvals to embark on mass vaccinations. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - August 21, 2018 Category: African Health Source Type: news

FDA Warns Against Long - Term Azithromycin Use for Some
Warning for blood cancer patients who have undergone donor stem cell transplant (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 13, 2018 Category: Cancer & Oncology Tags: Infections, Oncology, Pharmacy, Pulmonology, Journal, Source Type: news

FDA Warns Against Long-Term Azithromycin Use for Some
MONDAY, Aug. 13, 2018 -- The U.S. Food and Drug Administration is warning patients with cancers of the blood or lymph nodes who undergo a donor stem cell transplant not to take azithromycin, as long-term use of the antibiotic has been associated... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 13, 2018 Category: Pharmaceuticals Source Type: news

FDA: Don't Use Azithromycin for Lung Condition in Cancer Patients FDA: Don't Use Azithromycin for Lung Condition in Cancer Patients
The FDA warns of an increased risk for relapse of hematologic malignancy and for death when azithromycin is used to prevent bronchiolitis obliterans syndrome in hematopoietic stem cell transplant patients.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 3, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

FDA warns about increased risk of cancer relapse with long-term use of azithromycin (Zithromax, Zmax) antibiotic after donor stem cell transplant
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 3, 2018 Category: Drugs & Pharmacology Source Type: news

Blood biomarker can help predict disease progression in patients with COPD
(Elsevier) Some patients with COPD demonstrate signs of accelerated aging. In a new study published in the journal CHEST ® researchers report that measuring blood telomeres, a marker of aging of cells, can be used to predict future risk of the disease worsening or death. Further, they have determined that the drug azithromycin may help patients with short telomeres, an indicator of more rapid biological aging, stave off negative clinical outcomes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 12, 2018 Category: International Medicine & Public Health Source Type: news

Azithromycin Cuts Pulmonary Exacerbation in CF With Early Pa
WEDNESDAY, June 27, 2018 -- For children with cystic fibrosis (CF) and early Pseudomonas aeruginosa (Pa) infection, the risk of pulmonary exacerbation is significantly reduced with the addition of azithromycin to tobramycin inhalation solution... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 27, 2018 Category: Pharmaceuticals Source Type: news

Pfizer announces extension of Zithromax ® Antibiotic Donation Program through 2025 to help eliminate world's leading infectious cause of blindness
Pfizer Inc. will extend its donation of the antibiotic Zithromax® (azithromycin) to the International Trachoma Initiative through 2025, building on the company's 20-years of work to help eliminate the world's leading infectious cause of blindness. Approximately 163 million people are at risk of developing the disease and this recommitment ensures that Pfizer, through the International Trachoma Initiative (ITI), will continue to provide trachoma endemic countries with donated antibiotics that are a critical component of the global strategy to eliminate this neglected tropical disease (NTD). (Source: World Pharma News)
Source: World Pharma News - June 14, 2018 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news

Macrolide antibiotics for bronchiectasis
This Cochrane Review of 15 RCTs found that long-term macrolide therapy may reduce the frequency of exacerbations and improve quality of life, although supporting evidence is derived mainly from studies of azithromycin, and predominantly among adults rather than children. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - June 1, 2018 Category: Consumer Health News Source Type: news

Randomised controlled trial tests azithromycin efficacy for asthma exacerbation
Wed, 05/16/2018 - 15:05News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - May 16, 2018 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Azithromycin: A Generic Antibiotic That Continues To Provide Surprising Life-Saving Benefits
Decades after it was synthesized in a lab in Groton, Connecticut, new uses of azithromycin are still being found to save lives. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 15, 2018 Category: Pharmaceuticals Authors: John LaMattina, Contributor Source Type: news

Trovan - Zithromax (Trovafloxacin and Azithromycin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 14, 2018 Category: Drugs & Pharmacology Source Type: news

Azithromycin (Azasite) Ophthalmic Solution 1% (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - May 9, 2018 Category: Drugs & Pharmacology Source Type: news

Zithromax (Azithromycin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - May 8, 2018 Category: Drugs & Pharmacology Source Type: news

Common antibiotic significantly reduces child deaths across Africa
Giving the antibiotic azithromycin twice a year to young children in sub-Saharan Africa reduced childhood deaths by 13.5%, a new study has shown. (Source: CNN.com - Health)
Source: CNN.com - Health - April 26, 2018 Category: Consumer Health News Source Type: news

Preventive use of common antibiotic reduces child mortality in sub-Saharan Africa
(University of California - San Francisco) Treating young children in Sub-Saharan Africa with azithromycin, a safe, inexpensive, and widely used antibiotic, significantly reduced deaths of children under five in a large randomized trial led by scientists at UC San Francisco. The finding could help speed progress toward the United Nations' goal of ending preventable child deaths by 2030. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 25, 2018 Category: Infectious Diseases Source Type: news

The World ’s First Case of Drug-Resistant ‘Super Gonorrhea’ Has Been Confirmed
This report is one more confirmation of our greatest fear: drug-resistant gonorrhea spreading around the globe,” David Harvey, executive director of the National Coalition of STD Directors, told CNN. The patient, who first sought medical care in early 2018, is being treated with an intravenous course of ertapenem, a powerful antibiotic typically used, at least in the U.S., for “serious infections in hospitalized patients,” according to the National Institutes of Health. The results of his next test are expected in mid-April. Gonorrhea is one of the world’s most common STIs, affecting 78 million peop...
Source: TIME: Health - March 30, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime public health Source Type: news

U.K. Man Has World's Worst Case of Super-Gonorrhea
It's the first case of the sexually-transmitted disease that could not be cured with the main antibiotic treatment, a combination of azithromycin and ceftriaxone, according to Public Health England, BBC News reported. (Source: WebMD Health)
Source: WebMD Health - March 29, 2018 Category: Consumer Health News Source Type: news

How A Man Caught The World's Strongest Super Gonorrhea To Date
This is the first reported case in the world of N. gonorrhea which has both high-level resistance to azithromycin and resistance to ceftriaxone. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 29, 2018 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

How A Man Caught The World's Strongest Super Gonorrhea To Date
This is the first reported case in the world of N. gonorrhea which has both high-level resistance to azithromycin and resistance to ceftriaxone. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - March 29, 2018 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

Azithromycin: Hope for Idiopathic Pulmonary Fibrosis? Azithromycin: Hope for Idiopathic Pulmonary Fibrosis?
Dr Nicholas Gross on a flawed but promising study of patients with acute exacerbations of this too-often fatal condition.Medscape Pulmonary Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 23, 2018 Category: Consumer Health News Tags: Pulmonary Medicine Viewpoint Source Type: news

Gonorrhea in China shows waning susceptibility to WHO-recommended antibiotics
(PLOS) Neisseria gonorrhoeae strains resistant to azithromycin and/or with decreased susceptibility to ceftriaxone are common in China, according to a prevalence study published this week in PLOS Medicine. The study also showed that the prevalence of dual resistance in N. gonorrhoeae isolates increased from 2013 to 2016. The results suggest that dual therapy with azithromycin and ceftriaxone, recommended by WHO and many countries to treat gonorrhea, may not prove effective in China. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 6, 2018 Category: Infectious Diseases Source Type: news

Can I Give Cholera Vaccine?
Discussion Cholera is caused by more than 200 serogroups of Vibrio cholerae, a Gram-negative rod that is waterborne. Only two (serogroup O1 which causes about 99% of the cases, and O139) cause disease. There are biotypes of each of these serotypes. The only known hosts are humans. The organism colonizes the epithelial lining of the gut. Cholera toxin is produced by some species and if produced binds to specific receptors on host cells, activating a series of steps which cases massive loss of sodium, potassium, chloride, hydrogen carbonate, and fluids in vomitus and feces. A review of causes of diarrhea can be found here. ...
Source: PediatricEducation.org - November 27, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Single Dose of Azithromycin Effective for Latent Yaws Single Dose of Azithromycin Effective for Latent Yaws
Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - November 12, 2017 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

No Added Value of a Macrolide in Pediatric Pneumonia No Added Value of a Macrolide in Pediatric Pneumonia
The combination of a macrolide like azithromycin with a beta-lactam is no more effective than a beta-lactam alone in treating children hospitalized with pneumonia, according to results from the Etiology of Pneumonia in the Community Study.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - November 2, 2017 Category: Allergy & Immunology Tags: Pediatrics News Source Type: news