The impact of nasal use of azelastine and mometasone furoate on drug-induced sleep endoscopy
CONCLUSIONS: This study first investigated nasal mometasone furoate and azelastine on DISE. This study showed that prior use of nasal mometasone furoate or azelastine before DISE did not affect the amount of secretion, tolerance level, severity, and configuration of obstruction.PMID:38436176 | DOI:10.26355/eurrev_202402_35464 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: H I Altiner Y Basal U O Akyildiz Source Type: research

The impact of nasal use of azelastine and mometasone furoate on drug-induced sleep endoscopy
CONCLUSIONS: This study first investigated nasal mometasone furoate and azelastine on DISE. This study showed that prior use of nasal mometasone furoate or azelastine before DISE did not affect the amount of secretion, tolerance level, severity, and configuration of obstruction.PMID:38436176 | DOI:10.26355/eurrev_202402_35464 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 4, 2024 Category: Drugs & Pharmacology Authors: H I Altiner Y Basal U O Akyildiz Source Type: research

The impact of nasal use of azelastine and mometasone furoate on drug-induced sleep endoscopy
CONCLUSIONS: This study first investigated nasal mometasone furoate and azelastine on DISE. This study showed that prior use of nasal mometasone furoate or azelastine before DISE did not affect the amount of secretion, tolerance level, severity, and configuration of obstruction.PMID:38436176 | DOI:10.26355/eurrev_202402_35464 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: H I Altiner Y Basal U O Akyildiz Source Type: research

The impact of nasal use of azelastine and mometasone furoate on drug-induced sleep endoscopy
CONCLUSIONS: This study first investigated nasal mometasone furoate and azelastine on DISE. This study showed that prior use of nasal mometasone furoate or azelastine before DISE did not affect the amount of secretion, tolerance level, severity, and configuration of obstruction.PMID:38436176 | DOI:10.26355/eurrev_202402_35464 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 4, 2024 Category: Drugs & Pharmacology Authors: H I Altiner Y Basal U O Akyildiz Source Type: research

The impact of nasal use of azelastine and mometasone furoate on drug-induced sleep endoscopy
CONCLUSIONS: This study first investigated nasal mometasone furoate and azelastine on DISE. This study showed that prior use of nasal mometasone furoate or azelastine before DISE did not affect the amount of secretion, tolerance level, severity, and configuration of obstruction.PMID:38436176 | DOI:10.26355/eurrev_202402_35464 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: H I Altiner Y Basal U O Akyildiz Source Type: research

Method validation and characterization of stress degradation products of azelastine hydrochloride using LC-UV/PDA and LC-Q/TOF-MS studies
CONCLUSIONS: Six degradation products generated from stress degradation studies on azelastine HCl were adequately resolved through LC-UV/PDA studies followed by method validation. These were successfully identified and characterized through LC-Q/TOF-MS studies, and the degradation pathways for the generation of these products from the drug have been postulated.PMID:38351666 | DOI:10.1002/rcm.9712 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - February 14, 2024 Category: Chemistry Authors: Sudhanshu Shekhar Alka Bali Source Type: research

Fluticasone Furoate versus Fluticasone Propionate/Azelastine in Moderate-to-Severe Persistent Perennial Allergic Rhinitis from Thai Adult chronic Rhinitis prospective Cohort (TARhiC)
According to the 2-week randomized trials in patients with seasonal allergic rhinitis, intranasal corticosteroid (INCS)/intranasal antihistamine was more effective than INCS monotherapy. However, studies longer than 2-week duration in perennial allergic rhinitis (PAR) comparing their efficacy are limited. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Piyaporn Chokevittaya, Chamard Wongsa, Irin Vichara-Anont, Thanachit Krikeerati, Mongkhon Sompornrattanaphan, Kawita Atipas, Dichapong Kanjanawasee, Triphoom Suwanwech, Pongsakorn Tantilipikorn, Torpong Thongngarm Source Type: research

Viruses, Vol. 15, Pages 2300: Antiviral Potential of Azelastine against Major Respiratory Viruses
Valeria Szijarto The Coronavirus Disease 2019 (COVID-19) pandemic and the subsequent increase in respiratory viral infections highlight the need for broad-spectrum antivirals to enable a quick and efficient reaction to current and emerging viral outbreaks. We previously demonstrated that the antihistamine azelastine hydrochloride (azelastine-HCl) exhibited in vitro antiviral activity against SARS-CoV-2. Furthermore, in a phase 2 clinical study, a commercial azelastine-containing nasal spray significantly reduced the viral load in SARS-CoV-2-infected individuals. Here, we evaluate the efficacy of azelastine-HCl agains...
Source: Viruses - November 23, 2023 Category: Virology Authors: Katrin Fischhuber Zolt án Bánki Janine Kimpel Natalie Kragl Annika R össler Annika Bolze Brigitte Muellauer Joachim Angerer G ábor Nagy Eszter Nagy Valeria Szijarto Tags: Article Source Type: research