Azelastine/fluticasone and allergic rhinitis in clinical practice
(Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - September 13, 2023 Category: ENT & OMF Source Type: research

The Comparative Bioavailability of Fluticasone and Azelastine Delivered as a Single Fixed Dose Combination (MP-AzeFlu) in Comparison to Two Different Formulations of Azelastine and Fluticasone Propionate Following Intranasal Administration in Healthy Chinese Volunteers
(Source: Journal of Asthma and Allergy)
Source: Journal of Asthma and Allergy - June 30, 2023 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development
Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - May 17, 2023 Category: Microbiology Authors: Jasmin Kuratli Cory Ann Leonard Robert Schoborg Nicole Borel Source Type: research

Fluticasone Propionate with Azelastine Versus Standalone Fluticasone Propionate as Nasal Spray in Allergic Rhinitis: A Prospective Comparative Study in a Rural Population of Northern India
Conclusions: According to results obtained from the current study, while both fluticasone propionate with azelastine nasal spray and standalone fluticasone propionate nasal spray are widely used for control of symptoms in PER, the former offers better results with significant reduction of symptoms when compared to the latter. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - May 6, 2023 Category: ENT & OMF Source Type: research

The Rising Cost of Rhinologic Medications
CONCLUSION: The rising cost of highly utilized medications contribute to increased patient acquisition costs and may pose barriers of drug adherence to particularly vulnerable populations.PMID:37098404 | DOI:10.1016/j.anai.2023.04.013 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 25, 2023 Category: Allergy & Immunology Authors: Milind Vasudev Sina J Torabi Lauren Michelle Leo L T Meller Jack L Birkenbeuel Kelsey M Roman Theodore V Nguyen Edward C Kuan Source Type: research