Anti-chlamydial effects of azelastine hydrochloride and the impact of the histamine H1 receptor on chlamydial development

Conclusion. Accordingly, we conclude that azelastine anti-chlamydial effects are not restricted to a specific chlamydial species, strain or culture model, and are probably not mediated by H1R antagonism. Thus, it appears likely that off-target mechanisms of azelastine may explain our observations.PMID:37195751 | DOI:10.1099/jmm.0.001691
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research