The prevalence of helminthiases in North-Western Siberia rural indigenous and long-term resident people in 1988-89 and 2018-19
Int J Circumpolar Health. 2021 Dec;80(1):1917270. doi: 10.1080/22423982.2021.1917270.ABSTRACTThe aim of this work was to compare the prevalence of opisthorchiasis, diphyllobothriasis, and ascariasis among the rural indigenous and long-term resident people of Khanty-Mansi Autonomous Okrug (KMAO) in the years 1988-89 and 2018-19. Helminth infections were identified by faecal microscopic examinations conducted during health check-ups. We analysed 399 medical records for years 1988-89 and 549 records for 2018-19. There were found a decrease in the prevalence of ascariasis among the indigenous people, but the region remains a h...
Source: International Journal of Circumpolar Health - April 26, 2021 Category: International Medicine & Public Health Authors: Andrey Kozlov Galina Vershubskaya Source Type: research

Rodent Models for the Study of Soil-Transmitted Helminths: A Proteomics Approach
Soil-transmitted helminths (STH) affect hundreds of millions worldwide and are some of the most important neglected tropical diseases in terms of morbidity. Due to the difficulty in studying STH human infections, rodent models have become increasingly used, mainly because of their similarities in life cycle. Ascaris suum and Trichuris muris have been proven appropriate and low maintenance models for the study of ascariasis and trichuriasis. In the case of hookworms, despite most of the murine models do not fully reproduce the life cycle of Necator americanus, their proteomic similarity makes them highly suitable for the de...
Source: Frontiers in cellular and infection microbiology - April 22, 2021 Category: Microbiology Source Type: research

Treatment response and long-term outcomes in biliary ascariasis: A prospective study
Publication date: Available online 19 March 2021Source: Arab Journal of GastroenterologyAuthor(s): Partha Sarathi Patra, Abhishek Das, S.K. Mahiuddin Ahmed, Souveek Mitra, Gopal Krishna Dhali (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - March 20, 2021 Category: Gastroenterology Source Type: research

The Effect of Drug Pricing on Outpatient Payments and Treatment for Three Soil-Transmitted Helminth Infections in the United States, 2010-2017
Am J Trop Med Hyg. 2021 Mar 8:tpmd201452. doi: 10.4269/ajtmh.20-1452. Online ahead of print.ABSTRACTThe price of certain antiparasitic drugs (e.g., albendazole and mebendazole) has dramatically increased since 2010. The effect of these rising prices on treatment costs and use of standard of care (SOC) drugs is unknown. To measure the impact of drug prices on overall outpatient cost and quality of care, we identified outpatient visits associated with ascariasis, hookworm, and trichuriasis infections from the 2010 to 2017 MarketScan Commercial Claims and Encounters and Multi-state Medicaid databases using Truven Health Marke...
Source: Am J Trop Med Hyg - March 8, 2021 Category: Infectious Diseases Authors: Heesoo Joo Junsoo Lee Brian A Maskery Chanhyun Park Jonathan D Alpern Christina R Phares Michelle Weinberg William M Stauffer Source Type: research

The Effect of Drug Pricing on Outpatient Payments and Treatment for Three Soil-Transmitted Helminth Infections in the United States, 2010-2017
Am J Trop Med Hyg. 2021 Mar 8:tpmd201452. doi: 10.4269/ajtmh.20-1452. Online ahead of print.ABSTRACTThe price of certain antiparasitic drugs (e.g., albendazole and mebendazole) has dramatically increased since 2010. The effect of these rising prices on treatment costs and use of standard of care (SOC) drugs is unknown. To measure the impact of drug prices on overall outpatient cost and quality of care, we identified outpatient visits associated with ascariasis, hookworm, and trichuriasis infections from the 2010 to 2017 MarketScan Commercial Claims and Encounters and Multi-state Medicaid databases using Truven Health Marke...
Source: The American Journal of Tropical Medicine and Hygiene - March 8, 2021 Category: Tropical Medicine Authors: Heesoo Joo Junsoo Lee Brian A Maskery Chanhyun Park Jonathan D Alpern Christina R Phares Michelle Weinberg William M Stauffer Source Type: research

The Effect of Drug Pricing on Outpatient Payments and Treatment for Three Soil-Transmitted Helminth Infections in the United States, 2010-2017
Am J Trop Med Hyg. 2021 Mar 8:tpmd201452. doi: 10.4269/ajtmh.20-1452. Online ahead of print.ABSTRACTThe price of certain antiparasitic drugs (e.g., albendazole and mebendazole) has dramatically increased since 2010. The effect of these rising prices on treatment costs and use of standard of care (SOC) drugs is unknown. To measure the impact of drug prices on overall outpatient cost and quality of care, we identified outpatient visits associated with ascariasis, hookworm, and trichuriasis infections from the 2010 to 2017 MarketScan Commercial Claims and Encounters and Multi-state Medicaid databases using Truven Health Marke...
Source: Am J Trop Med Hyg - March 8, 2021 Category: Infectious Diseases Authors: Heesoo Joo Junsoo Lee Brian A Maskery Chanhyun Park Jonathan D Alpern Christina R Phares Michelle Weinberg William M Stauffer Source Type: research

The Effect of Drug Pricing on Outpatient Payments and Treatment for Three Soil-Transmitted Helminth Infections in the United States, 2010-2017
Am J Trop Med Hyg. 2021 Mar 8:tpmd201452. doi: 10.4269/ajtmh.20-1452. Online ahead of print.ABSTRACTThe price of certain antiparasitic drugs (e.g., albendazole and mebendazole) has dramatically increased since 2010. The effect of these rising prices on treatment costs and use of standard of care (SOC) drugs is unknown. To measure the impact of drug prices on overall outpatient cost and quality of care, we identified outpatient visits associated with ascariasis, hookworm, and trichuriasis infections from the 2010 to 2017 MarketScan Commercial Claims and Encounters and Multi-state Medicaid databases using Truven Health Marke...
Source: The American Journal of Tropical Medicine and Hygiene - March 8, 2021 Category: Tropical Medicine Authors: Heesoo Joo Junsoo Lee Brian A Maskery Chanhyun Park Jonathan D Alpern Christina R Phares Michelle Weinberg William M Stauffer Source Type: research

The Effect of Drug Pricing on Outpatient Payments and Treatment for Three Soil-Transmitted Helminth Infections in the United States, 2010-2017
Am J Trop Med Hyg. 2021 Mar 8:tpmd201452. doi: 10.4269/ajtmh.20-1452. Online ahead of print.ABSTRACTThe price of certain antiparasitic drugs (e.g., albendazole and mebendazole) has dramatically increased since 2010. The effect of these rising prices on treatment costs and use of standard of care (SOC) drugs is unknown. To measure the impact of drug prices on overall outpatient cost and quality of care, we identified outpatient visits associated with ascariasis, hookworm, and trichuriasis infections from the 2010 to 2017 MarketScan Commercial Claims and Encounters and Multi-state Medicaid databases using Truven Health Marke...
Source: Am J Trop Med Hyg - March 8, 2021 Category: Infectious Diseases Authors: Heesoo Joo Junsoo Lee Brian A Maskery Chanhyun Park Jonathan D Alpern Christina R Phares Michelle Weinberg William M Stauffer Source Type: research

Socioenvironmental Factors Influencing Distribution and Intensity of Soil-Transmitted Helminthiasis in the Brazilian Amazon: Challenges for the 2030 Agenda
J Trop Med. 2021 Feb 4;2021:6610181. doi: 10.1155/2021/6610181. eCollection 2021.ABSTRACTSoil-transmitted helminthiasis (STHs) are poverty-related diseases with high prevalence rates in developing countries. The present study aims to describe the epidemiological scenario of STHs in an urban population in the Brazilian Amazon. A cross-sectional survey (n = 349 children aged 1-15 years) was carried out to obtain faecal samples and sociodemographic and sanitation data. Among the children, 143 (41%) were positive for at least one STH. Prevalence rates of infections by A. lumbricoides, T. trichiura, and hookworms were 24.4%, 42...
Source: Journal of Tropical Medicine - February 22, 2021 Category: Tropical Medicine Authors: Deiviane Aparecida Calegar Polyanna Ara újo Alves Bacelar Brenda Bulsara Costa Evangelista Kerla Joeline Lima Monteiro J éssica Pereira Dos Santos Mayron Morais Almeida M árcio Neves Bóia Filipe Anibal Carvalho-Costa Source Type: research