Uncommon ascaris induced eosinophilic myocarditis simulating acute coronary syndrome without ST segment elevation: A case report
CONCLUSION: The aim of this work was to increase recognition of EM in the light of this clinical case report of ascaris lumbricoides associated myocarditis simulating an acute coronary syndrome without ST segment elevation.PMID:35495403 | PMC:PMC9052135 | DOI:10.1016/j.amsu.2022.103522 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2022 Category: Internal Medicine Authors: Chaimae Toutai Ilham Benahmed Asmae Mrabet Nabila Ismaili Noha Elouafi Source Type: research

Endemic Thoracic Infections in Sub-Saharan Africa
Although many of the thoracic infections endemic to Africa are also present around the world, this article focuses on entities that are emerging or disproportionately affect populations living in sub-Saharan Africa. Important emerging or reemerging viral and bacterial diseases that commonly affect the lung include dengue fever, plague, leptospirosis, and rickettsioses. Most parasitic infections endemic to Africa can also manifest within the thorax, including malaria, amebiasis, hydatid disease, schistosomiasis, paragonimiasis, ascariasis, strongyloidiasis and cysticercosis. Level of sanitation, interaction between humans a...
Source: Radiologic Clinics of North America - May 1, 2022 Category: Radiology Authors: Chara E. Rydzak, Ana Santos Lima, Gustavo S.P. Meirelles Source Type: research

Cross-Sectional Study on Assessment of Frequency of Intestinal Helminth Infections and Its Related Risk Factors among School Children from Adola Town, Ethiopia
Biomed Res Int. 2022 Apr 11;2022:5908938. doi: 10.1155/2022/5908938. eCollection 2022.ABSTRACTThe three main intestinal helminth infections (IHIs), ascariasis, trichuriasis, and hookworm, are common clinical disorders worldwide. These IHIs are more prevalent in tropics and subtropical countries especially in developing countries like sub-Saharan Africa responsible for morbidity, mortality, and physical as well as intellectual growth retardation in children. In Ethiopia, the burden of IHIs appears in all ages mainly due to factors like lack of education, low socio-economic status, and inadequate supply of drugs and proper a...
Source: Biomed Res - April 21, 2022 Category: Research Authors: Edaso Amana Husen Geremew Tafesse Sunil Tulshiram Hajare Nitin Mahendra Chauhan Rajesh J Sharma Vijay J Upadhye Source Type: research

Cross-Sectional Study on Assessment of Frequency of Intestinal Helminth Infections and Its Related Risk Factors among School Children from Adola Town, Ethiopia
Biomed Res Int. 2022 Apr 11;2022:5908938. doi: 10.1155/2022/5908938. eCollection 2022.ABSTRACTThe three main intestinal helminth infections (IHIs), ascariasis, trichuriasis, and hookworm, are common clinical disorders worldwide. These IHIs are more prevalent in tropics and subtropical countries especially in developing countries like sub-Saharan Africa responsible for morbidity, mortality, and physical as well as intellectual growth retardation in children. In Ethiopia, the burden of IHIs appears in all ages mainly due to factors like lack of education, low socio-economic status, and inadequate supply of drugs and proper a...
Source: Biomed Res - April 21, 2022 Category: Research Authors: Edaso Amana Husen Geremew Tafesse Sunil Tulshiram Hajare Nitin Mahendra Chauhan Rajesh J Sharma Vijay J Upadhye Source Type: research

Cross-Sectional Study on Assessment of Frequency of Intestinal Helminth Infections and Its Related Risk Factors among School Children from Adola Town, Ethiopia
Biomed Res Int. 2022 Apr 11;2022:5908938. doi: 10.1155/2022/5908938. eCollection 2022.ABSTRACTThe three main intestinal helminth infections (IHIs), ascariasis, trichuriasis, and hookworm, are common clinical disorders worldwide. These IHIs are more prevalent in tropics and subtropical countries especially in developing countries like sub-Saharan Africa responsible for morbidity, mortality, and physical as well as intellectual growth retardation in children. In Ethiopia, the burden of IHIs appears in all ages mainly due to factors like lack of education, low socio-economic status, and inadequate supply of drugs and proper a...
Source: Biomed Res - April 21, 2022 Category: Research Authors: Edaso Amana Husen Geremew Tafesse Sunil Tulshiram Hajare Nitin Mahendra Chauhan Rajesh J Sharma Vijay J Upadhye Source Type: research

Cross-Sectional Study on Assessment of Frequency of Intestinal Helminth Infections and Its Related Risk Factors among School Children from Adola Town, Ethiopia
Biomed Res Int. 2022 Apr 11;2022:5908938. doi: 10.1155/2022/5908938. eCollection 2022.ABSTRACTThe three main intestinal helminth infections (IHIs), ascariasis, trichuriasis, and hookworm, are common clinical disorders worldwide. These IHIs are more prevalent in tropics and subtropical countries especially in developing countries like sub-Saharan Africa responsible for morbidity, mortality, and physical as well as intellectual growth retardation in children. In Ethiopia, the burden of IHIs appears in all ages mainly due to factors like lack of education, low socio-economic status, and inadequate supply of drugs and proper a...
Source: Biomed Res - April 21, 2022 Category: Research Authors: Edaso Amana Husen Geremew Tafesse Sunil Tulshiram Hajare Nitin Mahendra Chauhan Rajesh J Sharma Vijay J Upadhye Source Type: research

Resurgence of intestinal ascariasis among adults: radiological diagnosis and clinical implications
AbstractTo report the radiological features of intestinal ascariasis and to review the clinical implications of this re-emerging disease for adult population of the USA. This retrospective observational study involved 12 adult patients, whose radiological examinations disclosed unsuspected presence of ascaris in their intestinal tract. They were evaluated by computed tomography of the abdomen with oral contrast, small bowel series with barium, and magnetic resonance enterography. This series included 7 men and 5 women, who ranged in age from 19 to 72  years (mean age 48 years). The typical configuration of ascaris within...
Source: Abdominal Imaging - January 11, 2022 Category: Radiology Source Type: research

ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Ascaris suum Infection
Control of human ascariasis, the most prevalent neglected tropical disease globally affecting 450 million people, mostly relies on mass drug administration of anthelmintics. However, chemotherapy alone is not efficient due to the high re-infection rate for people who live in the endemic area. The development of a vaccine that reduces the intensity of infection and maintains lower morbidity should be the primary target for infection control. Previously, our group demonstrated that immunization with crude Ascaris antigens in mice induced an IgG-mediated protective response with significant worm reduction. Here, we aimed to d...
Source: Frontiers in Immunology - December 21, 2021 Category: Allergy & Immunology Source Type: research

Transient < i > Ascaris suum < /i > larval migration induces intractable chronic pulmonary disease and anemia in mice
by Yifan Wu, Evan Li, Morgan Knight, Grace Adeniyi-Ipadeola, Li-zhen Song, Alan R. Burns, Ana Clara Gazzinelli-Guimaraes, Ricardo Fujiwara, Maria Elena Bottazzi, Jill E. Weatherhead Ascariasis is one of the most common infections in the world and associated with significant global morbidity.Ascaris larval migration through the host ’s lungs is essential for larval development but leads to an exaggerated type-2 host immune response manifesting clinically as acute allergic airway disease. However, whetherAscaris larval migration can subsequently lead to chronic lung diseases remains unknown. Here, we demonstrate that a si...
Source: PLoS Neglected Tropical Diseases - December 16, 2021 Category: Tropical Medicine Authors: Yifan Wu Source Type: research

The yin and yang of human soil-transmitted helminth infections
Int J Parasitol. 2021 Nov 10:S0020-7519(21)00304-0. doi: 10.1016/j.ijpara.2021.11.001. Online ahead of print.ABSTRACTThe major soil-transmitted helminths (STHs) that infect humans are the roundworms, whipworms and hookworms. STH infections rank among the most important neglected tropical diseases in terms of morbidity, and almost one billion people are still infected with at least one species. While anthelmintic drugs are available, they do not offer long term protection against reinfection, precipitating the need for vaccines that provide long-term immunologic defense. Vaccine discovery and development is in advanced clin...
Source: International Journal for Parasitology - November 14, 2021 Category: Parasitology Authors: Alex Loukas Rick M Maizels Peter J Hotez Source Type: research

The yin and yang of human soil-transmitted helminth infections
Int J Parasitol. 2021 Nov 10:S0020-7519(21)00304-0. doi: 10.1016/j.ijpara.2021.11.001. Online ahead of print.ABSTRACTThe major soil-transmitted helminths (STHs) that infect humans are the roundworms, whipworms and hookworms. STH infections rank among the most important neglected tropical diseases in terms of morbidity, and almost one billion people are still infected with at least one species. While anthelmintic drugs are available, they do not offer long term protection against reinfection, precipitating the need for vaccines that provide long-term immunologic defense. Vaccine discovery and development is in advanced clin...
Source: International Journal for Parasitology - November 14, 2021 Category: Parasitology Authors: Alex Loukas Rick M Maizels Peter J Hotez Source Type: research

Retrospective analysis and time series forecasting with automated machine learning of ascariasis, enterobiasis and cystic echinococcosis in Romania
The objective was to gain deep understanding of the epidemiological distribution of three selected and highly endemic parasitic diseases, namely, ascariasis, enterobiasis and cystic echinococcosis (CE), during this period and forecast their courses for the ensuing two years. Through descriptive and inferential analysis, we observed a decline in case numbers for all three NTD. Several distributional particularities at regional level e merged. Furthermore, we performed predictions using a novel automated time series (AutoTS) machine learning tool and could interestingly show a stable course for these parasitic NTD. Such pred...
Source: PLoS Neglected Tropical Diseases - November 1, 2021 Category: Tropical Medicine Authors: Johannes Benecke Source Type: research

Soil-transmitted helminthiasis in China: A national survey in 2014-2015
Conclusions/SignificanceThis survey demonstrated the continuous decrease of STH in rural China. However, endemicity still prevails in the western areas of the country. Hookworm, especiallyN.americanus, is becoming the predominant species. Older farmers in western China should be prioritized for control due to the high prevalence of hookworm. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - October 19, 2021 Category: Tropical Medicine Authors: Ying-Dan Chen Source Type: research