Toxocariasis: A neglected infection for the Anthropocene epoch.
Abstract While ascariasis, trichuriasis, and hookworm infection dominate global efforts to control human soil-transmitted helminth infections, a picture is unfolding to suggest that toxocariasis is now a fourth and perhaps equally important parasitic disease. Toxocara eggs are widespread in the environment and practically ubiquitous in the soils of many subtropical and tropical regions of Asia, Africa, and the Americas. Human zoonotic infection is also highly prevalent in these areas, based on serologic studies to detect anti-Toxocara antibodies. The relevance of these findings to human and animal disease ...
Source: Advances in Parasitology - May 11, 2020 Category: Parasitology Authors: Hotez PJ Tags: Adv Parasitol Source Type: research

Fungal and Parasitic Infections of the Liver
Hepatosplenic candidiasis and other fungal infections of the liver are uncommon in healthy individuals; however, high index of suspicion is essential in immunocompromised patients with prolonged fever. Parasitic infections are protozoan or helminthic; their distribution and epidemiology are variable among different world regions. Clonorchiasis, opisthorchiasis, fascioliasis, and ascariasis are helminthic infections that commonly involve the biliary systems. Signs and symptoms of cholangitis require prompt management to relieve biliary obstruction; addition of antihelminthic agents is essential. Parasitic infections are mos...
Source: Gastroenterology Clinics of North America - May 8, 2020 Category: Gastroenterology Authors: Sirina Ekpanyapong, K. Rajender Reddy Source Type: research

Anthelmintic drugs for treating ascariasis.
CONCLUSIONS: Single-dose of albendazole, mebendazole, and ivermectin all appeared effective against Ascaris lumbricoides infection, yielding high parasitological cure and large reductions in eggs excreted, with no differences detected between them. The drugs appear to be safe to treat children and adults with confirmed Ascaris infection. There is little to choose between drugs and regimens in terms of cure or adverse events. PMID: 32289194 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 13, 2020 Category: General Medicine Authors: Conterno LO, Turchi MD, Corrêa I, Monteiro de Barros Almeida RA Tags: Cochrane Database Syst Rev Source Type: research

Biliary ascariasis and severe bacterial outcomes: Report of three cases from a paediatric hospital in Brazil
Ascariasis, caused by the nematode Ascaris lumbricoides, is a soil-transmitted helminthiasis that affects about 1 billion people around the world, mainly children and populations living under poor conditions of basic sanitation in developing countries (de Lima Corvino and Horrall, 2019). It is estimated that this disease, which can greatly impact health and quality of life, infects 29.7 million Brazilians (Scholte et al., 2013), leading to harmful conditions such as long-term cognitive impairment and malnutrition (de Lima Corvino and Horrall, 2019). (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 29, 2020 Category: Infectious Diseases Authors: Breno Lima de Almeida, Daniel Vicente Silva, Mateus Santana do Ros ário, Bruno Simões Dias Gonçalves, Míria Guimarães Nunes, André Luis Chukr Mafra Ney, Celia Silvany, Isadora Cristina de Siqueira Tags: Case Report Source Type: research

Biliary Ascariasis and severe bacterial outcomes: Report of three cases from a Pediatric Hospital in Brazil
Ascariasis, caused by the nematode Ascaris lumbricoides, is a soil-transmitted helminthiasis that affects about one billion people around the world, mainly children and populations living under poor conditions of basic sanitation in developing countries (de Lima Corvino and Horrall, 2019). It is estimated that this disease, which can greatly impact health and quality of life, infects 29.7 million Brazilians (Scholte et al., 2013), leading to harmful conditions, such as long-term cognitive impairment and malnutrition (de Lima Corvino and Horrall, 2019). (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - March 29, 2020 Category: Infectious Diseases Authors: Breno Lima de Almeida, Daniel Vicente Silva, Mateus Santana do Ros ário, Bruno Simões Dias Gonçalves, Míria Guimarães Nunes, André Luis Chukr Mafra Ney, Celia Silvany, Isadora Cristina de Siqueira Tags: Case Report Source Type: research