Artichoke (Cynara scolymus L.) water extract alleviates palmitate-induced insulin resistance in HepG2 hepatocytes via the activation of IRS1/PI3K/AKT/FoxO1 and GSK-3 β signaling pathway
This study aims to eval... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - December 15, 2023 Category: Complementary Medicine Authors: Aihua Deng, Yun Wang, Kerui Huang, Peng Xie, Ping Mo, Fengying Liu, Jun Chen, Kaiyi Chen, Yun Wang and Bing Xiao Tags: Research Source Type: research
A nutraceutical with Citrus bergamia and Cynara cardunculus improves endothelial function in adults with non-alcoholic fatty liver disease
CONCLUSIONS: A nutraceutical containing bergamot and artichoke extracts improves peripheral vascular endothelial function in adults with hepatic steatosis and early phase of atherosclerosis.PMID:38042043 | DOI:10.1016/j.nut.2023.112294 (Source: Atherosclerosis)
Source: Atherosclerosis - December 2, 2023 Category: Cardiology Authors: Samantha Maurotti Roberta Pujia Yvelise Ferro Rosario Mare Raffaella Russo Adriana Coppola Carmine Gazzaruso Tiziana Montalcini Arturo Pujia Sara Paone Vincenzo Mollace Elisa Mazza Source Type: research
Jerusalem artichoke diversity in T ürkiye: comparative analysis of clone and organ-based biochemical composition
In this study, biochemical analyses were performed for the first time on 22 different Jerusalem artichokes clones collected from different regions of Türkiye and samples from three different organs of each clone, considering the interaction effects. As a result of the study, the interaction effect of clones and sampled organs was found significant for total flavonoids, ascorbic acid, total chlorophyll, pH, H2O2 removal capacity, total dry matter, water soluble dry matter and antioxidant capacity via FRAP. According to the correlation analysis, the highest coefficient among the parameters in the tuber was between titratabl...
Source: Natural Product Research - November 15, 2023 Category: Biochemistry Authors: Fatih Hanci Zelal Inan Akife Dalda Şekerci Ayd ın Uzun Source Type: research
Jerusalem artichoke diversity in T ürkiye: comparative analysis of clone and organ-based biochemical composition
In this study, biochemical analyses were performed for the first time on 22 different Jerusalem artichokes clones collected from different regions of Türkiye and samples from three different organs of each clone, considering the interaction effects. As a result of the study, the interaction effect of clones and sampled organs was found significant for total flavonoids, ascorbic acid, total chlorophyll, pH, H2O2 removal capacity, total dry matter, water soluble dry matter and antioxidant capacity via FRAP. According to the correlation analysis, the highest coefficient among the parameters in the tuber was between titratabl...
Source: Natural Product Research - November 15, 2023 Category: Biochemistry Authors: Fatih Hanci Zelal Inan Akife Dalda Şekerci Ayd ın Uzun Source Type: research
Isolation and Purification of Harpagogenin as an Nrf2-ARE Activator from the Tubers of Chinese Artichoke (Stachys sieboldii)
This study examined the effect of the Chinese artichoke extracts on the nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway that induces the expression of antioxidant enzymes to explore its novel characteristics. Hot water extracts exhibited relatively high ARE activity. ARE activity was observed in two fractions when the hot water extracts were separated in the presence of trifluoroacetic acid using HPLC. Conversely, the highly active fraction disappeared when the hot water extracts were separated in the absence of trifluoroacetic acid. These results indicate that acidic degradati...
Source: Biological and Pharmaceutical Bulletin - November 1, 2023 Category: Drugs & Pharmacology Authors: Yasuhiko Izumi Harue Kataoka Yuki Takada-Takatori Yutaka Koyama Kazuhiro Irie Akinori Akaike Toshiaki Kume Source Type: research
Isolation and Purification of Harpagogenin as an Nrf2-ARE Activator from the Tubers of Chinese Artichoke (Stachys sieboldii)
This study examined the effect of the Chinese artichoke extracts on the nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway that induces the expression of antioxidant enzymes to explore its novel characteristics. Hot water extracts exhibited relatively high ARE activity. ARE activity was observed in two fractions when the hot water extracts were separated in the presence of trifluoroacetic acid using HPLC. Conversely, the highly active fraction disappeared when the hot water extracts were separated in the absence of trifluoroacetic acid. These results indicate that acidic degradati...
Source: Biological and Pharmaceutical Bulletin - November 1, 2023 Category: Drugs & Pharmacology Authors: Yasuhiko Izumi Harue Kataoka Yuki Takada-Takatori Yutaka Koyama Kazuhiro Irie Akinori Akaike Toshiaki Kume Source Type: research
Isolation and Purification of Harpagogenin as an Nrf2-ARE Activator from the Tubers of Chinese Artichoke (Stachys sieboldii)
This study examined the effect of the Chinese artichoke extracts on the nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway that induces the expression of antioxidant enzymes to explore its novel characteristics. Hot water extracts exhibited relatively high ARE activity. ARE activity was observed in two fractions when the hot water extracts were separated in the presence of trifluoroacetic acid using HPLC. Conversely, the highly active fraction disappeared when the hot water extracts were separated in the absence of trifluoroacetic acid. These results indicate that acidic degradati...
Source: Biological and Pharmaceutical Bulletin - November 1, 2023 Category: Drugs & Pharmacology Authors: Yasuhiko Izumi Harue Kataoka Yuki Takada-Takatori Yutaka Koyama Kazuhiro Irie Akinori Akaike Toshiaki Kume Source Type: research
Isolation and Purification of Harpagogenin as an Nrf2-ARE Activator from the Tubers of Chinese Artichoke (Stachys sieboldii)
This study examined the effect of the Chinese artichoke extracts on the nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway that induces the expression of antioxidant enzymes to explore its novel characteristics. Hot water extracts exhibited relatively high ARE activity. ARE activity was observed in two fractions when the hot water extracts were separated in the presence of trifluoroacetic acid using HPLC. Conversely, the highly active fraction disappeared when the hot water extracts were separated in the absence of trifluoroacetic acid. These results indicate that acidic degradati...
Source: Biological and Pharmaceutical Bulletin - November 1, 2023 Category: Drugs & Pharmacology Authors: Yasuhiko Izumi Harue Kataoka Yuki Takada-Takatori Yutaka Koyama Kazuhiro Irie Akinori Akaike Toshiaki Kume Source Type: research
Viruses, Vol. 15, Pages 2170: Identification, Sequencing, and Molecular Analysis of RNA2 of Artichoke Italian Latent Virus Isolates from Known Hosts and a New Host Plant Species
This study adds insights into the variability of AILV and the occurrence of recombination that may condition plant infection. (Source: Viruses)
Source: Viruses - October 28, 2023 Category: Virology Authors: Toufic Elbeaino Amani Ben Slimen Imen Belgacem Mounia Mnari-Hattab Roberta Span ò Michele Digiaro Ahmed Abdelkhalek Tags: Article Source Type: research
Identification and expression analysis of miR396 and its target genes in Jerusalem artichoke under temperature stress
In this study, we successfully cloned and identified three MIR396s (htu-MIR396a/b/c) and their corresponding miR396s (htu-miR396a/b/c). Additionally, we identified nine target genes, comprising seven GRFs (HtGRF3/4/6/9/10/12/13), one WRKY (HtWRKY40), and one SCL (HtSCL33), using comprehensive sRNAome, transcriptome, and degradome data of Jerusalem artichoke. The expression patterns of htu-MIR396s, htu-miR396s, and their targets in tissues and under temperature stress were analyzed by qRT-PCR and RNA-seq. Notably, htu-MIR396s exhibited high expression in seedling stems, while htu-miR396s predominantly expressed in seedling ...
Source: Gene - October 20, 2023 Category: Genetics & Stem Cells Authors: Baishui Ding Yang Yue Xi Chen Xiaohua Long Zhaosheng Zhou Source Type: research
Unveiling HSP40/60/70/90/100 gene families and abiotic stress responses in Jerusalem artichoke
Gene. 2023 Oct 18:147912. doi: 10.1016/j.gene.2023.147912. Online ahead of print.ABSTRACTHeat shock proteins (HSPs) are essential for plant growth, development, and stress adaptation. However, their roles in Jerusalem artichoke are largely unexplored. Using bioinformatics, we classified 143 HSP genes into distinct families: HSP40 (82 genes), HSP60 (22 genes), HSP70 (29 genes), HSP90 (6 genes), and HSP100 (4 genes). Our analysis covered their traits, evolution, and structures. Using RNA-seq data, we uncovered unique expression patterns of these HSP genes across growth stages and tissues. Notably, HSP40, HSP60, HSP70, HSP90,...
Source: Gene - October 20, 2023 Category: Genetics & Stem Cells Authors: Wencai Ren Baishui Ding Wenhan Dong Yang Yue Xiaohua Long Zhaosheng Zhou Source Type: research
Identification and expression analysis of miR396 and its target genes in Jerusalem artichoke under temperature stress
In this study, we successfully cloned and identified three MIR396s (htu-MIR396a/b/c) and their corresponding miR396s (htu-miR396a/b/c). Additionally, we identified nine target genes, comprising seven GRFs (HtGRF3/4/6/9/10/12/13), one WRKY (HtWRKY40), and one SCL (HtSCL33), using comprehensive sRNAome, transcriptome, and degradome data of Jerusalem artichoke. The expression patterns of htu-MIR396s, htu-miR396s, and their targets in tissues and under temperature stress were analyzed by qRT-PCR and RNA-seq. Notably, htu-MIR396s exhibited high expression in seedling stems, while htu-miR396s predominantly expressed in seedling ...
Source: Gene - October 20, 2023 Category: Genetics & Stem Cells Authors: Baishui Ding Yang Yue Xi Chen Xiaohua Long Zhaosheng Zhou Source Type: research
Three arms, double-blind, non-inferiority, randomized clinical study testing the lipid-lowering effect of a novel dietary supplement containing red yeast rice and artichoke extracts compared to Armolipid Plus < sup > ® < /sup > and placebo
CONCLUSIONS: Patients with polygenic hypercholesterolemia experienced a significant improvement in several cardiovascular risk factors in both ATC and Armolipid Plus® groups.PMID:37732047 | PMC:PMC10507752 | DOI:10.5114/aoms/167969 (Source: Archives of Medical Science)
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Arrigo F G Cicero Federica Fogacci Giuliano Tocci Sergio D'Addato Elisa Grandi Maciej Banach Claudio Borghi Source Type: research
