The Effect of a Diet Enriched with < em > Jerusalem artichoke < /em > , Inulin, and Fluoxetine on Cognitive Functions, Neurogenesis, and the Composition of the Intestinal Microbiota in Mice
Curr Issues Mol Biol. 2023 Mar 21;45(3):2561-2579. doi: 10.3390/cimb45030168.ABSTRACTThe aim of the study was to assess the effect of long-term administration of natural prebiotics: Jerusalem artichoke (topinambur, TPB) and inulin (INU) as well as one of the most popular antidepressants, fluoxetine (FLU), on the proliferation of neural stem cells, learning and memory functions, and the composition of the intestinal microbiota in mice. Cognitive functions were assessed using the Morris Water Maze (MWM)Test. Cells were counted using a confocal microscope and ImageJ software. We performed 16S rRNA sequencing to assess changes...
Source: Current Issues in Molecular Biology - March 28, 2023 Category: Molecular Biology Authors: Aleksandra Szewczyk Marta Andres-Mach Miros ław Zagaja Agnieszka Kaczmarczyk-Ziemba Maciej Maj Joanna Szala-Rycaj Source Type: research
The Effect of a Diet Enriched with < em > Jerusalem artichoke < /em > , Inulin, and Fluoxetine on Cognitive Functions, Neurogenesis, and the Composition of the Intestinal Microbiota in Mice
Curr Issues Mol Biol. 2023 Mar 21;45(3):2561-2579. doi: 10.3390/cimb45030168.ABSTRACTThe aim of the study was to assess the effect of long-term administration of natural prebiotics: Jerusalem artichoke (topinambur, TPB) and inulin (INU) as well as one of the most popular antidepressants, fluoxetine (FLU), on the proliferation of neural stem cells, learning and memory functions, and the composition of the intestinal microbiota in mice. Cognitive functions were assessed using the Morris Water Maze (MWM)Test. Cells were counted using a confocal microscope and ImageJ software. We performed 16S rRNA sequencing to assess changes...
Source: Current Issues in Molecular Biology - March 28, 2023 Category: Molecular Biology Authors: Aleksandra Szewczyk Marta Andres-Mach Miros ław Zagaja Agnieszka Kaczmarczyk-Ziemba Maciej Maj Joanna Szala-Rycaj Source Type: research
The Effect of a Diet Enriched with < em > Jerusalem artichoke < /em > , Inulin, and Fluoxetine on Cognitive Functions, Neurogenesis, and the Composition of the Intestinal Microbiota in Mice
Curr Issues Mol Biol. 2023 Mar 21;45(3):2561-2579. doi: 10.3390/cimb45030168.ABSTRACTThe aim of the study was to assess the effect of long-term administration of natural prebiotics: Jerusalem artichoke (topinambur, TPB) and inulin (INU) as well as one of the most popular antidepressants, fluoxetine (FLU), on the proliferation of neural stem cells, learning and memory functions, and the composition of the intestinal microbiota in mice. Cognitive functions were assessed using the Morris Water Maze (MWM)Test. Cells were counted using a confocal microscope and ImageJ software. We performed 16S rRNA sequencing to assess changes...
Source: Current Issues in Molecular Biology - March 28, 2023 Category: Molecular Biology Authors: Aleksandra Szewczyk Marta Andres-Mach Miros ław Zagaja Agnieszka Kaczmarczyk-Ziemba Maciej Maj Joanna Szala-Rycaj Source Type: research
Molecules, Vol. 28, Pages 2475: Wild Artichoke (Cynara cardunculus subsp. sylvestris, Asteraceae) Leaf Extract: Phenolic Profile and Oxidative Stress Inhibitory Effects on HepG2 Cells
In this study, the phenolic profile and cell-free antioxidant properties of the leaf aqueous extract of wild artichokes grown in Sicily (Italy) were investigated. The crude extract was also tested in cells for its antioxidant characteristics and potential oxidative stress inhibitory effects. To resemble the features of the early stage of mild steatosis in humans, human HepG2 cells treated with free fatty acids at the concentration of 1.5 mM were used. HPLC-DAD analysis revealed the presence of several phenolic acids (caffeoylquinic acids) and flavonoids (luteolin and apigenin derivatives). At the same time, DPPH assay show...
Source: Molecules - March 8, 2023 Category: Chemistry Authors: Rosaria Acquaviva Giuseppe Antonio Malfa Rosa Santangelo Simone Bianchi Francesco Pappalardo Maria Fernanda Taviano Natalizia Miceli Claudia Di Giacomo Barbara Tomasello Tags: Article Source Type: research
Saccharified and Fermented Helianthus tuberosus L. Beverage Attenuates High-Fat Diet-Inducible Metabolic Complications in C57BL/6 Mice
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - February 1, 2023 Category: Nutrition Authors: Hee-Kyoung Son Joomin Lee Jaemin Byun Jae-Joon Lee Source Type: research
Molecules, Vol. 28, Pages 1363: Byproducts of Globe Artichoke and Cauliflower Production as a New Source of Bioactive Compounds in the Green Economy Perspective: An NMR Study
ovich Sobolev
The recovery of bioactive compounds from crop byproducts leads to a new perspective way of waste reutilization as a part of the circular economy. The present study aimed at an exhaustive metabolite profile characterization of globe artichoke and cauliflower byproducts (leaves, stalks, and florets for cauliflower only) as a prerequisite for their valorization and future implementations. The metabolite profile of aqueous and organic extracts of byproducts was analyzed using the NMR-based metabolomics approach. Free amino acids, organic acids, sugars, polyols, polyphenols, amines, glucosinolates, fatty acids...
Source: Molecules - January 31, 2023 Category: Chemistry Authors: Cinzia Ingallina Giacomo Di Matteo Mattia Spano Erica Acciaro Enio Campiglia Luisa Mannina Anatoly Petrovich Sobolev Tags: Article Source Type: research
Molecules, Vol. 28, Pages 1129: Successive Solvent Extraction, Characterization and Antioxidant Activities of Cardoon Waste (Leaves and Stems) Extracts: Comparative Study
ehmi Boufahja
The main interest in the valorization of vegetable wastes is due to the peculiarity of their chemical composition in substances that present important properties. Among these substances, antioxidants could replace those industrially manufactured. In the present study, three solvents of different polarities (hexane, ethanol, and water) were applied for the extraction of phenolic compounds from Cynara cardunculus L. waste using two extraction methods: Soxhlet Extraction (SE) and Ultrasonic-Assisted Extraction (UAE). The obtained extracts were then characterized by Fourier-Transform Infrared (FTIR) spectrosc...
Source: Molecules - January 23, 2023 Category: Chemistry Authors: Meryem Hajji Nabih Hamza Boulika Maryam El Hajam Mohammed I. Alghonaim Noureddine Idrissi Kandri Sulaiman A. Alsalamah Fehmi Boufahja Tags: Article Source Type: research
Optimization of inulinase production using Jerusalem artichoke (Helianthus tuberosus) as cheap substrate and comparison with pure chicory inulin
(Source: Preparative Biochemistry)
Source: Preparative Biochemistry - January 5, 2023 Category: Biochemistry Authors: Canli Tasar, Ozden Tasar, Gani Erhan Source Type: research
Preparation of microcrystalline cellulose from agricultural residues and their application as polylactic acid/microcrystalline cellulose composite films for the preservation of Lanzhou lily
Int J Biol Macromol. 2022 Dec 20;227:827-838. doi: 10.1016/j.ijbiomac.2022.12.198. Online ahead of print.ABSTRACTMicrocrystalline celluloses were isolated from four agricultural residues, including sweet sorghum stalk, Jerusalem artichoke stalk, grains stillage, and Chinese herb residue, and characterized in terms of physicochemical and structural properties. The obtained microcrystalline celluloses were composited with polylactic acid as a packing film for the preservation of Lanzhou lily. All the agricultural residues-derived microcrystalline celluloses were in cellulose Iβ structure with high purity and good thermal st...
Source: International Journal of Biological Macromolecules - December 23, 2022 Category: Biochemistry Authors: Haiwei Ren Zhihang Xu Ming Gao Xueye Xing Zhe Ling Lichao Pan Yaqin Tian Yi Zheng Wenguang Fan Weixia Yang Source Type: research
One-Pot Tandem Transformation of Inulin as Fructose-Rich Platform Towards 5-Hydroxymethylfurfural: Feedstock Advantages, Acid-Site Regulation and Solvent Effects
ChemSusChem. 2022 Dec 22. doi: 10.1002/cssc.202201936. Online ahead of print.ABSTRACTThe valorization of non-grain biomass feedstocks to value-added chemicals, polymers and alternative fuels is a crucial route for the utilization of renewable resources. Inulin belongs to a type of fructans, which is a pivotal platform bridging upstream fructose-rich biomass feedstocks typically represented by Jerusalem artichoke and downstream platform molecules such as alcohols, aldehydes and acids. Fructose can be directly obtained from the inulin hydrolysis and further converted into various platform chemicals, which is a more environme...
Source: ChemSusChem - December 22, 2022 Category: Chemistry Authors: Jian Xiong Xuebin Lu Wei Li Shijie Yang Rui Zhang Xiaoyun Li Jinfeng Han Dan Li Zhihao Yu Source Type: research
Molecules, Vol. 27, Pages 8962: Synchronous Extraction, Antioxidant Activity Evaluation, and Composition Analysis of Carbohydrates and Polyphenols Present in Artichoke Bud
This study investigated the optimization of ultrasonic-assisted aqueous two-phase synchronous extraction of carbohydrates and polyphenols present in artichoke bud, evaluated their antioxidant activities in vitro, and analyzed the composition of carbohydrates and polyphenols by high-performance liquid chromatography (HPLC). The powder mass, ultrasonic time, ammonium sulfate concentration, and alcohol&ndash;water ratio were considered the influencing factors based on the single-factor experiment results, and a dual-response surface model was designed to optimize the synchronous extraction process to extract carbohydr...
Source: Molecules - December 16, 2022 Category: Chemistry Authors: Xiao Lin Xian-Kun Lu Kai-Hao Zhu Xin-Yang Jiang Jiong-Chao Chen Pei-Zheng Yan Dong-Sheng Zhao Tags: Article Source Type: research
Uptake of different pharmaceuticals in soil and mycorrhizal artichokes from wastewater
Environ Sci Pollut Res Int. 2022 Dec 7. doi: 10.1007/s11356-022-24475-7. Online ahead of print.NO ABSTRACTPMID:36474042 | DOI:10.1007/s11356-022-24475-7 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - December 6, 2022 Category: Environmental Health Authors: Francesco De Mastro Gennaro Brunetti Giuseppe De Mastro Claudia Ruta Donato Stea Sapia Murgolo Cristina De Ceglie Giuseppe Mascolo Filomena Sannino Claudio Cocozza Andreina Traversa Source Type: research
Uptake of different pharmaceuticals in soil and mycorrhizal artichokes from wastewater
Environ Sci Pollut Res Int. 2022 Dec 7. doi: 10.1007/s11356-022-24475-7. Online ahead of print.NO ABSTRACTPMID:36474042 | DOI:10.1007/s11356-022-24475-7 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - December 6, 2022 Category: Environmental Health Authors: Francesco De Mastro Gennaro Brunetti Giuseppe De Mastro Claudia Ruta Donato Stea Sapia Murgolo Cristina De Ceglie Giuseppe Mascolo Filomena Sannino Claudio Cocozza Andreina Traversa Source Type: research
An artichoke-derived compound increase [Ca2+]i by inhibiting Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) and activates airway ciliary beating in humans
Conclusions: An artichoke-derived compound A increased CBF via an increase of [cAMP]i induced by elevation of [Ca2+]i due to inhibition of SERCA in human airway ciliary cells. (Source: European Respiratory Journal)
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Todo, N., Noriyama, K., Tamiya, N., Shigeta, M., Nakamura, S., Takayama, K., Ashihara, E., Hosogi, S. Tags: 03.02 - Airway cell biology and immunopathology Source Type: research
Water extract from artichoke ameliorates high-fat diet-induced non-alcoholic fatty liver disease in rats
The “multiple-hit” hypothesis is currently the most widely accepted theory for non-alcoholic fatty liver disease (NAFLD) pathogenesis. The present study aimed to investigate the effects of the water extract of... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - November 24, 2022 Category: Complementary Medicine Authors: Aihua Deng, Fengying Liu, Xuchong Tang, Yun Wang, Peng Xie, Qifu Yang and Bing Xiao Tags: Research Source Type: research
