Comprehensive identification of pathogenic microbes and antimicrobial resistance genes in food products using nanopore sequencing-based metagenomics
In conclusion, this comprehensive study offers invaluable data that can contribute to food safety assessments and serve as a basis for quality indicators.PMID:38637066 | DOI:10.1016/j.fm.2024.104493 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Annie Wing-Tung Lee Iain Chi-Fung Ng Evelyn Yin-Kwan Wong Ivan Tak-Fai Wong Rebecca Po-Po Sze Kit-Yu Chan Tsz-Yan So Zhipeng Zhang Sharon Ka-Yee Fung Sally Choi-Ying Wong Wing-Yin Tam Hiu-Yin Lao Lam-Kwong Lee Jake Siu-Lun Leung Chloe Toi-Mei Chan Timothy Source Type: research

Common food preservatives impose distinct selective pressures on Salmonella Typhimurium planktonic and biofilm populations
In conclusion, we showed that preservatives affect biofilm formation and bacterial growth in a compound specific manner. We showed trade-offs between biofilm formation and preservative tolerance, but no antibiotic cross-tolerance. This indicates that bacterial adaptation to continuous preservative exposure, is unlikely to affect food safety or contribute to antibiotic resistance.PMID:38637079 | DOI:10.1016/j.fm.2024.104517 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Justin Abi Assaf Emma R Holden Eleftheria Trampari Mark A Webber Source Type: research

Common food preservatives impose distinct selective pressures on Salmonella Typhimurium planktonic and biofilm populations
In conclusion, we showed that preservatives affect biofilm formation and bacterial growth in a compound specific manner. We showed trade-offs between biofilm formation and preservative tolerance, but no antibiotic cross-tolerance. This indicates that bacterial adaptation to continuous preservative exposure, is unlikely to affect food safety or contribute to antibiotic resistance.PMID:38637079 | DOI:10.1016/j.fm.2024.104517 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Justin Abi Assaf Emma R Holden Eleftheria Trampari Mark A Webber Source Type: research

Comprehensive identification of pathogenic microbes and antimicrobial resistance genes in food products using nanopore sequencing-based metagenomics
In conclusion, this comprehensive study offers invaluable data that can contribute to food safety assessments and serve as a basis for quality indicators.PMID:38637066 | DOI:10.1016/j.fm.2024.104493 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Annie Wing-Tung Lee Iain Chi-Fung Ng Evelyn Yin-Kwan Wong Ivan Tak-Fai Wong Rebecca Po-Po Sze Kit-Yu Chan Tsz-Yan So Zhipeng Zhang Sharon Ka-Yee Fung Sally Choi-Ying Wong Wing-Yin Tam Hiu-Yin Lao Lam-Kwong Lee Jake Siu-Lun Leung Chloe Toi-Mei Chan Timothy Source Type: research

Comprehensive identification of pathogenic microbes and antimicrobial resistance genes in food products using nanopore sequencing-based metagenomics
In conclusion, this comprehensive study offers invaluable data that can contribute to food safety assessments and serve as a basis for quality indicators.PMID:38637066 | DOI:10.1016/j.fm.2024.104493 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Annie Wing-Tung Lee Iain Chi-Fung Ng Evelyn Yin-Kwan Wong Ivan Tak-Fai Wong Rebecca Po-Po Sze Kit-Yu Chan Tsz-Yan So Zhipeng Zhang Sharon Ka-Yee Fung Sally Choi-Ying Wong Wing-Yin Tam Hiu-Yin Lao Lam-Kwong Lee Jake Siu-Lun Leung Chloe Toi-Mei Chan Timothy Source Type: research

Common food preservatives impose distinct selective pressures on Salmonella Typhimurium planktonic and biofilm populations
In conclusion, we showed that preservatives affect biofilm formation and bacterial growth in a compound specific manner. We showed trade-offs between biofilm formation and preservative tolerance, but no antibiotic cross-tolerance. This indicates that bacterial adaptation to continuous preservative exposure, is unlikely to affect food safety or contribute to antibiotic resistance.PMID:38637079 | DOI:10.1016/j.fm.2024.104517 (Source: Food Microbiology)
Source: Food Microbiology - April 18, 2024 Category: Food Science Authors: Justin Abi Assaf Emma R Holden Eleftheria Trampari Mark A Webber Source Type: research

Performing Trichomonas vaginalis culture in research studies in low-resource settings
Trichomonas vaginalis is the most common non-viral sexually transmitted infection (STI) worldwide, with an estimated 156 million new cases per year globally.1 Incidence and prevalence are highest in low-income settings, especially the African region.2 If symptomatic, T. vaginalis causes vaginal discharge and dysuria. Untreated T. vaginalis has been associated with adverse birth outcomes and an increased risk of HIV acquisition and transmission.3 Antimicrobial resistance to 5-nitroimidazole agents such as metronidazole is reported to occur in about 5%–10% of isolates in the USA.4 T. vaginalis can be diagnosed by wet m...
Source: Sexually Transmitted Infections - April 18, 2024 Category: Sexual Medicine Authors: Peters, R. P. H., Mdingi, M. M., Gigi, R. M. S., Lim, L., Medina-Marino, A., Klausner, J. D., Muzny, C. A. Tags: PostScript Source Type: research

BASHH feedback from the 2023 IUSTI-Europe conference in Malta
There is a growing relationship between BASHH and IUSTI.1 In 2023, several BASHH scholars were invited to give feedback on the IUSTI conference in Malta. Asymptomatic STI screening: Chris Kenyon, (Belgium) Despite good evidence for HIV and syphilis screening in asymptomatic patients, evidence is lacking for other STIs, for example, Neisseria gonorrhoeae and Chlamydia trachomatis. Kenyon et al2 highlighted the potential harms of widespread screening for asymptomatic STIs, particularly in HIV-pre-exposure prophylaxis (HIV-PrEP) cohorts, namely increased antimicrobial consumption and antimicrobial resistance (AMR). In Belgium...
Source: Sexually Transmitted Infections - April 18, 2024 Category: Sexual Medicine Authors: Richardson, D., Butler, M., Bull Olozabal, O., Gupta, N., Naser, F., Sultan, B., Caswell, R. J. Tags: BASHH column Source Type: research

Emergence of OXA-48-producing Klebsiella pneumoniae in Lithuania, 2023: a multi-cluster, multi-hospital outbreak
In 2023, an increase of OXA-48-producingKlebsiella pneumoniae was noticed by the Lithuanian National Public Health Surveillance Laboratory. Whole genome sequencing (WGS) of 106 OXA-48-producingK. pneumoniae isolates revealed three distinct clusters of carbapenemase-producingK. pneumoniae high-risk clones, including sequence type (ST) 45 (n = 35 isolates), ST392 (n = 32) and ST395 (n = 28), involving six, six and nine hospitals in different regions, respectively. These results enabled targeted investigation and control, and underscore the value of national WGS-based surveillance for antim...
Source: Eurosurveillance - April 18, 2024 Category: Infectious Diseases Authors: Paulius Grei čius, Marius Linkevicius, Jelena Razmuk, Jekaterina Sinotova, Erik Alm, Olov Svartström, Valeria Bortolaia, Eglė Kudirkienė, Louise Roer, Rene S Hendriksen, Gabija Tamoliūnaitė, Daniel Palm, Dominique L Monnet, Anke Kohlenberg and Algir Source Type: research

Lipase and Protease Production Ability of Multi-drug Resistant Bacteria Worsens the Outcomes of Wound Infections
CONCLUSION: In conclusion, the findings suggest that lipases and proteases produced by bacteria could contribute to drug resistance and act as virulence factors in the development of surgical site infections. Understanding the role of these enzymes may inform strategies for preventing and managing post-surgical wound infections more effectively.PMID:38629357 | DOI:10.2174/0113816128302189240402043330 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - April 17, 2024 Category: Drugs & Pharmacology Authors: Attaur Rahman Saiqa Sardar Zeeshan Niaz Asif Khan None Sheheryar Abdulwahed Fahad Alrefaei Muhammad Hamayun Sajid Ali Source Type: research

Assessment of Antibiotic Resistance Genes in Soils Polluted by Chemical and Technogenic Ways with Poly-Aromatic Hydrocarbons and Heavy Metals
This study focused on assessing the prevalence and distribution of antibiotic-resistance genes in polluted soil ecosystems impacted by industrial enterprises in southern Russia. Metagenomic analysis was conducted on soil samples collected from polluted sites using various approaches, and the prevalence of antibiotic-resistance genes was investigated. The results revealed that efflux-encoding pump sequences were the most widely represented group of genes, while genes whose products replaced antibiotic targets were less represented. The level of soil contamination increased, and there was an increase in the total number of a...
Source: Environmental Research - April 17, 2024 Category: Environmental Health Authors: Ming Hung Wong Tatiana Minkina Nikita Vasilchenko Svetlana Sushkova Yanina Delegan Anuj Ranjan Pallavi Saxena Sarieh Tarigholizadeh Tamara Dudnikova Andrey Barbashev Aleksey Maksimov Alexandr Faenson R ıdvan Kızılkaya Source Type: research

Epidemiology and antimicrobial susceptibility profiles of Enterobacterales causing bloodstream infections before and during COVID-19 pandemic: Results of the Study for Monitoring Antimicrobial Resistance Trends (SMART) in Taiwan, 2018-2021
CONCLUSIONS: The COVID-19 pandemic appears to be associated with a general decrease in antimicrobial susceptibility rates among Enterobacterales causing BSIs in Taiwan. Continuous surveillance is crucial to monitor antimicrobial resistance during the pandemic and in the future.PMID:38632023 | DOI:10.1016/j.jmii.2024.04.004 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 17, 2024 Category: Microbiology Authors: Yu-Lin Lee Chun-Eng Liu Hung-Jen Tang Yu-Tsung Huang Yao-Shen Chen Po-Ren Hsueh SMART Taiwan Group Source Type: research

Lipase and Protease Production Ability of Multi-drug Resistant Bacteria Worsens the Outcomes of Wound Infections
CONCLUSION: In conclusion, the findings suggest that lipases and proteases produced by bacteria could contribute to drug resistance and act as virulence factors in the development of surgical site infections. Understanding the role of these enzymes may inform strategies for preventing and managing post-surgical wound infections more effectively.PMID:38629357 | DOI:10.2174/0113816128302189240402043330 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - April 17, 2024 Category: Drugs & Pharmacology Authors: Attaur Rahman Saiqa Sardar Zeeshan Niaz Asif Khan None Sheheryar Abdulwahed Fahad Alrefaei Muhammad Hamayun Sajid Ali Source Type: research

Burden of antimicrobial prescribing in primary care attributable to sore throat: a retrospective cohort study of patient record data
CONCLUSIONS: Frequency of antibiotic prescribing for sore throat is high and broad, despite Australian Therapeutic guideline recommendations. Multiple, sustained interventions to reduce prescribing, including availability of effective S. pyogenes vaccines that could reduce the incidence of streptococcal pharyngitis, could obviate the need to prescribe antibiotics and support ongoing efforts to promote antimicrobial stewardship.PMID:38632513 | PMC:PMC11022400 | DOI:10.1186/s12875-024-02371-y (Source: Primary Care)
Source: Primary Care - April 17, 2024 Category: Primary Care Authors: Kylie S Carville Niamh Meagher Yara-Natalie Abo Jo-Anne Manski-Nankervis James Fielding Andrew Steer Jodie McVernon David J Price Source Type: research

Assessment of Antibiotic Resistance Genes in Soils Polluted by Chemical and Technogenic Ways with Poly-Aromatic Hydrocarbons and Heavy Metals
This study focused on assessing the prevalence and distribution of antibiotic-resistance genes in polluted soil ecosystems impacted by industrial enterprises in southern Russia. Metagenomic analysis was conducted on soil samples collected from polluted sites using various approaches, and the prevalence of antibiotic-resistance genes was investigated. The results revealed that efflux-encoding pump sequences were the most widely represented group of genes, while genes whose products replaced antibiotic targets were less represented. The level of soil contamination increased, and there was an increase in the total number of a...
Source: Environmental Research - April 17, 2024 Category: Environmental Health Authors: Ming Hung Wong Tatiana Minkina Nikita Vasilchenko Svetlana Sushkova Yanina Delegan Anuj Ranjan Pallavi Saxena Sarieh Tarigholizadeh Tamara Dudnikova Andrey Barbashev Aleksey Maksimov Alexandr Faenson R ıdvan Kızılkaya Source Type: research