Apoptosis induction in human hepatoma cell line HepG2 cells by trans- Anethole via activation of mitochondria-mediated apoptotic pathways
In this study antiproliferative activities of trans-Anethole towards human liver cancer (HepG2), cervical cancer (HeLa) and breast cancer (MCF-7) cells were explored. trans-Anethole showed free radical scavenging potential as assessed by DNA nicking assay. trans-Anethole exhibited strong antiproliferative potential towards HepG2 cells compared to other cell lines. trans-Anethole strongly induced apoptosis in HepG2 cells by significantly upregulating the protein expressions of p53, Caspase-3 and Caspase-9 were assessed by western blotting analysis which highlighted apoptosis-inducing capacity of trans-Anethole against HepG2...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 2, 2023 Category: Drugs & Pharmacology Authors: Steve Harakeh Rajaa Al-Raddadi Turki Alamri Soad Al-Jaouni Mohammed Qari Yousef Qari Ajay Kumar Hanaa M Tashkandi Mohammed Moulay Alia M Aldahlawi Petr Slama Shafiul Haque Source Type: research

Associations of Death Anxiety, Inclusion of Smartphone in the Self, and Affiliation Motivation with Smartphone use and Addiction: A Multiple Mediation Study
This study is the first to apply terror management theory to understanding smartphone addiction by examining the potential indirect effect of death anxiety on smartphone addiction via inclusion of smartphone in the self (i.e., self-expansion), affiliation motivation (the desire to connect with others) for emotional support, and smartphone use. The sample consisted of 1483 Chinese university students between the ages of 18 and 24 (M = 19.14, SD = 1.03) who voluntarily completed an anonymous questionnaire survey. As hypothesized, death anxiety, inclusion of smartphone in the self, affiliation motivation, and smartphone use w...
Source: Omega - July 21, 2023 Category: Palliative Care Authors: Chun Feng Anise M S Wu Ke Yu Wen Zhao Ji-Kang Xu Source Type: research

Associations of Death Anxiety, Inclusion of Smartphone in the Self, and Affiliation Motivation with Smartphone use and Addiction: A Multiple Mediation Study
This study is the first to apply terror management theory to understanding smartphone addiction by examining the potential indirect effect of death anxiety on smartphone addiction via inclusion of smartphone in the self (i.e., self-expansion), affiliation motivation (the desire to connect with others) for emotional support, and smartphone use. The sample consisted of 1483 Chinese university students between the ages of 18 and 24 (M = 19.14, SD = 1.03) who voluntarily completed an anonymous questionnaire survey. As hypothesized, death anxiety, inclusion of smartphone in the self, affiliation motivation, and smartphone use w...
Source: Omega - July 21, 2023 Category: Palliative Care Authors: Chun Feng Anise M S Wu Ke Yu Wen Zhao Ji-Kang Xu Source Type: research

Associations of Death Anxiety, Inclusion of Smartphone in the Self, and Affiliation Motivation with Smartphone use and Addiction: A Multiple Mediation Study
This study is the first to apply terror management theory to understanding smartphone addiction by examining the potential indirect effect of death anxiety on smartphone addiction via inclusion of smartphone in the self (i.e., self-expansion), affiliation motivation (the desire to connect with others) for emotional support, and smartphone use. The sample consisted of 1483 Chinese university students between the ages of 18 and 24 (M = 19.14, SD = 1.03) who voluntarily completed an anonymous questionnaire survey. As hypothesized, death anxiety, inclusion of smartphone in the self, affiliation motivation, and smartphone use w...
Source: Omega - July 21, 2023 Category: Palliative Care Authors: Chun Feng Anise M S Wu Ke Yu Wen Zhao Ji-Kang Xu Source Type: research

Associations of Death Anxiety, Inclusion of Smartphone in the Self, and Affiliation Motivation with Smartphone use and Addiction: A Multiple Mediation Study
This study is the first to apply terror management theory to understanding smartphone addiction by examining the potential indirect effect of death anxiety on smartphone addiction via inclusion of smartphone in the self (i.e., self-expansion), affiliation motivation (the desire to connect with others) for emotional support, and smartphone use. The sample consisted of 1483 Chinese university students between the ages of 18 and 24 (M = 19.14, SD = 1.03) who voluntarily completed an anonymous questionnaire survey. As hypothesized, death anxiety, inclusion of smartphone in the self, affiliation motivation, and smartphone use w...
Source: Omega - July 21, 2023 Category: Palliative Care Authors: Chun Feng Anise M S Wu Ke Yu Wen Zhao Ji-Kang Xu Source Type: research

Associations of Death Anxiety, Inclusion of Smartphone in the Self, and Affiliation Motivation with Smartphone use and Addiction: A Multiple Mediation Study
This study is the first to apply terror management theory to understanding smartphone addiction by examining the potential indirect effect of death anxiety on smartphone addiction via inclusion of smartphone in the self (i.e., self-expansion), affiliation motivation (the desire to connect with others) for emotional support, and smartphone use. The sample consisted of 1483 Chinese university students between the ages of 18 and 24 (M = 19.14, SD = 1.03) who voluntarily completed an anonymous questionnaire survey. As hypothesized, death anxiety, inclusion of smartphone in the self, affiliation motivation, and smartphone use w...
Source: Omega - July 21, 2023 Category: Palliative Care Authors: Chun Feng Anise M S Wu Ke Yu Wen Zhao Ji-Kang Xu Source Type: research

Genomic Characterization of Alphacoronavirus from Mops condylurus bats in Nigeria
Virus Res. 2023 Jul 17:199174. doi: 10.1016/j.virusres.2023.199174. Online ahead of print.ABSTRACTCoronaviruses (CoVs) are responsible for sporadic, epidemic and pandemic respiratory diseases worldwide. Bats have been identified as the reservoir for CoVs. To increase the number of complete coronavirus genomes in Africa and to comprehend the molecular epidemiology of bat Alphacoronaviruses (AlphaCoVs), we used deep metagenomics shotgun sequencing to obtain three (3) near-complete genomes of AlphaCoVs from Mops condylurus (Angolan free-tailed) bat in Nigeria. Phylogenetic and pairwise identity analysis of open reading frame ...
Source: Virus Research - July 19, 2023 Category: Virology Authors: Uwem George Oluwadamilola George Judith Oguzie Oluwadamilola Osasona Babatunde Motayo Joshua Kamani Philomena Eromon Onikepe Folarin Anise Happi Isaac Komolafe Christian Happi Source Type: research

Genomic Characterization of Alphacoronavirus from Mops condylurus bats in Nigeria
Virus Res. 2023 Jul 17:199174. doi: 10.1016/j.virusres.2023.199174. Online ahead of print.ABSTRACTCoronaviruses (CoVs) are responsible for sporadic, epidemic and pandemic respiratory diseases worldwide. Bats have been identified as the reservoir for CoVs. To increase the number of complete coronavirus genomes in Africa and to comprehend the molecular epidemiology of bat Alphacoronaviruses (AlphaCoVs), we used deep metagenomics shotgun sequencing to obtain three (3) near-complete genomes of AlphaCoVs from Mops condylurus (Angolan free-tailed) bat in Nigeria. Phylogenetic and pairwise identity analysis of open reading frame ...
Source: Virus Research - July 19, 2023 Category: Virology Authors: Uwem George Oluwadamilola George Judith Oguzie Oluwadamilola Osasona Babatunde Motayo Joshua Kamani Philomena Eromon Onikepe Folarin Anise Happi Isaac Komolafe Christian Happi Source Type: research

Thermal desorption direct analysis in real ‐time high‐resolution mass spectrometry and machine learning allow the rapid authentication of ground black pepper and dried oregano: A proof‐of‐concept study
In this study, TD-DART-HRMS's utility for establishing spice authenticity was examined. To this aim, we directly analyzed authentic (typical) and adulterated (atypical) samples of ground black pepper and dried oregano in positive and negative ion modes. We analyzed a set of authentic ground black pepper samples (n = 14) originating from Brazil, Sri Lanka, Madagascar, Ecuador, Vietnam, Costa Rica, Indonesia, Cambodia, and adulterated samples (n = 25) consisting of mixtures of ground black pepper with this spice's nonfunctional by-products (pinheads or spent) or with different exogenous materials (olive kernel, green...
Source: Journal of Mass Spectrometry - July 4, 2023 Category: Chemistry Authors: Carmela Zacometti, Andrea Massaro, Tommaso Gioia, Stephane Lefevre, Aline Fr égière‐Salomon, Jean‐Louis Lafeuille, Ingrid Fiordaliso Candalino, Michele Suman, Roberto Piro, Alessandra Tata Tags: RESEARCH ARTICLE Source Type: research

Molecules, Vol. 28, Pages 5051: Comparison of Chemical Compositions and Antioxidant Activity of Essential Oils from Litsea Cubeba, Cinnamon, Anise, and Eucalyptus
ng Yanling Li The purpose of this study was to compare the antioxidant activity of litsea cubeba oil (LCO), cinnamon oil (CO), anise oil (AO), and eucalyptus oil (EUC) in vitro. The chemical compositions of the essential oils (EOs) were analyzed using gas chromatography-mass spectrometry (GC-MS). The antioxidant activity of the four EOs was evaluated through scavenging DPPH free radicals, chelating Fe2+, scavenging hydroxyl free radicals, and inhibiting yolk lipid peroxidation. The results showed that the major compounds found in LCO, CO, AO, and EUC are citral (64.29%), cinnamaldehyde (84.25%), anethole (78.51%), an...
Source: Molecules - June 28, 2023 Category: Chemistry Authors: Shutian Liu Chen Zhao Yuwei Cao Yan Li Zhuo Zhang Dechao Nie Weixuan Tang Yanling Li Tags: Article Source Type: research