Longer Duration DAPT in Medically Treated MI: What is the Strength of the Evidence?
A few studies have demonstrated the benefit of dual antiplatelet therapy (DAPT) during the first 3-12 months after AMI in medically managed patients (1-3). However, the benefit of more prolonged DAPT is poorly defined. The guidelines from national societies on the use of antiplatelet therapy after acute coronary syndromes (ACS) with or without percutaneous coronary intervention (PCI)/stenting continue to evolve, with more recent guidelines recommending a reduced duration and intensity of therapy in certain situations (4, 5). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Jeffrey L Anderson Tags: Editorial Source Type: research
How much data is enough data for imaging-guided PCI?
It is almost unanimously acknowledged that imaging guided percutaneous coronary intervention (PCI) improves outcomes, particularly in complex cases, where there's a mortality reduction of up to 50% [1,2]. Numerous studies have permeated the interventional landscape, that it is very difficult not to recommend intracoronary imaging when embarking on a more complex PCI. Just as no one questions the prescription of statins, for example, which reduce all-cause mortality by approximately 20 –30% (for both primary and secondary prevention) [3–5]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Alexandru Achim Source Type: research
Efficacy and safety of proton pump inhibitors on cardiovascular events and inflammatory factors in patients with upper gastrointestinal bleeding undergoing dual antiplatelet therapy
ConclusionMelena was the most frequent clinical manifestation in UGIB patients. The use of PPIs did not increase the risk of CVEs, and different PPI drugs did not affect the occurrence of CVEs. Furthermore, PPIs lowered CRP and TNF- α levels in serum of these patients. (Source: Inflammopharmacology)
Source: Inflammopharmacology - April 20, 2024 Category: Drugs & Pharmacology Source Type: research
Outcomes of Percutaneous Revascularization in Severe Ischemic Left Ventricular Dysfunction
This article presents a comprehensive review of coronary revascularization versus optimal medical therapy (OMT) in patients with severe ischemic left ventricular dysfunction.Recent FindingsThe REVIVED-BCIS2 trial randomized 700 patients with extensive coronary artery disease and left ventricular (LV) ejection fraction (LVEF) ≤ 35% and viability in more than four dysfunctional myocardial segments to percutaneous coronary intervention (PCI) plus OMT versus OMT alone. Over a median duration of 41 months, there was no difference in the composite of all-cause mortality, heart failure hospitalization, or improvement i n ...
Source: Current Cardiology Reports - April 20, 2024 Category: Cardiology Source Type: research
Longer-Duration Dual Antiplatelet Therapy in Medically-Treated Myocardial Infarction: What is the Strength of the Evidence?
A few studies have demonstrated the benefit of dual antiplatelet therapy (DAPT) during the first 3 to 12 months after acute myocardial infarction (AMI) in medically managed patients.1 –3 However, the benefit of more prolonged DAPT is poorly defined. The guidelines from national societies on the use of antiplatelet therapy after acute coronary syndromes (ACS) with or without percutaneous coronary intervention (PCI)/stenting continue to evolve, with more recent guidelines recomme nding a reduced duration and intensity of therapy in certain situations. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 20, 2024 Category: Cardiology Authors: Jeffrey L. Anderson Tags: Editorial Source Type: research
Impact of baseline yellow plaque assessed by coronary angioscopy on vascular response after stent implantation
CONCLUSIONS: Baseline YP affected the incidence of neoatherosclerosis as well as poor neointimal coverage at 11 months after stent implantation.PMID:38641319 | DOI:10.1016/j.jjcc.2024.04.004 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 19, 2024 Category: Cardiology Authors: Takuya Tsujimura Isamu Mizote Takayuki Ishihara Daisuke Nakamura Naotaka Okamoto Tatsuya Shiraki Naoki Itaya Mitsuyoshi Takahara Takaharu Nakayoshi Osamu Iida Yosuke Hata Masami Nishino Takafumi Ueno Daisaku Nakatani Shungo Hikoso Shinsuke Nanto Toshiaki Source Type: research
Efficacy of drug-coated balloon catheters for patients with short-term recurrent dysfunction of arteriovenous fistula
CONCLUSION: For AVFs that require frequent PTA over a short period of time, DCB improved the patency rate 3 months after PTA, but the improvement effect at 6 months was limited. The effect of DCB on prolonging the patency rate of AVFs that require frequent PTA over a short period of time may be correlated with the RI value before and after PTA.PMID:38641588 | DOI:10.1177/11297298241245853 (Source: The Journal of Vascular Access)
Source: The Journal of Vascular Access - April 19, 2024 Category: Surgery Authors: Sadanori Shintaku Hideki Kawanishi Masataka Banshodani Misaki Moriishi Naoko Takahashi Shinichiro Tsuchiya Source Type: research
Prognostic value of triglyceride-glucose index for left ventricular remodeling in nondiabetic ST-elevation myocardial infarction patients
Conclusion: A high TyG index level may contribute to the prediction of LVR in nondiabetic STEMI patients undergoing successful primary percutaneous coronary intervention.PMID:38639732 | DOI:10.2217/bmm-2024-0015 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - April 19, 2024 Category: Internal Medicine Authors: Tolga Han Efe Engin Alg ül Source Type: research
Evaluation on mortality predictors after emergent percutaneous coronary intervention in acute myocardial infarction with ventricular arrhythmias: Details not to be ignored?
We have read the article “Predictors of 30-day survival after emergent percutaneous coronary intervention following ventricular tachyarrhythmias complicating acute myocardial infarction” by Kohei Ukita et al [1]. In the study Immediate CPR and single-vessel CAD were significant predictors of 30-day survival after emerge nt PCI following VF or pulseless VT complicating AMI in patients . In univariate analysis, absence of diabetes and low arterial lactate value were associated with 30-day survival. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 19, 2024 Category: Cardiology Authors: Aytu ğ Al, Erdi Babayiğit, Bülent Görenek Source Type: research
Isthmin-1 alleviates cardiac ischemia/reperfusion injury through cGMP-PKG signaling pathway
CONCLUSION: ISM1 can protect against cardiac I/R injury through cGMP-PKG signaling pathway, and it is a promising therapeutic and predictive target of cardiac I/R injury.PMID:38637328 | DOI:10.1093/cvr/cvae077 (Source: Cell Research)
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Min Hu Xin Zhang Can Hu Zhen-Guo Ma Sha-Sha Wang Teng Teng Xiao-Feng Zeng Qi-Zhu Tang Source Type: research
Clinical and economic outcomes of assigning percutaneous coronary intervention patients to contrast-sparing strategies based on the predicted risk of contrast-induced acute kidney injury
CONCLUSIONS.: Assignment to contrast-sparing regimens at a predicted risk threshold close to the underlying incidence of CI-AKI is projected to result in significant clinical and economic benefits.PMID:38632967 | DOI:10.1080/13696998.2024.2334180 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 18, 2024 Category: Health Management Authors: Robert I Griffiths Aparna Bhave Alysha M McGovern Liesl M Hargens Craig A Solid Amit P Amin Source Type: research
Acute myocardial infarction with e ‐cigarette or vaping‐use associated lung injury in a young Filipino vape user
We present a 22-year-old Filipino male with sudden chest pain. He had no known comorbidities but had a two-year history of daily vape use. Work-up revealed elevated cardiac markers, anteroseptal ST-elevation myocardial infarction, hypokinesia of the anterior wall and interventricular septum, and an ejection fraction of 30%. Chest radiography showed consolidation pneumonia but culture studies and Biofire Pneumonia Panel were negative for microbial detection. Coronary angiography revealed chronic total obstruction of the mid-left anterior descending (LAD) and right coronary arteries (RCA). Percutaneous coronary angioplasty o...
Source: Respirology Case Reports - April 18, 2024 Category: Respiratory Medicine Authors: Margarita Isabel C. Fernandez,
Margaret Francine Co,
Janine Bianca Marie Rafael,
Regiel Christian Mag ‐usara,
Vanessa Ediza,
Rafael Luis Gavino,
Jan Christian Feliciano,
Nigel Jeronimo Santos,
Mark Andrian Yano,
Julian Alexander Huibonhoa,
Ric Tags: CASE REPORT Source Type: research
Evaluation of the efficacy of combined device strategies for long femoropopliteal artery disease
AbstractOne of the major problems associated with bare nitinol stent implantation is stent fracture, particularly in the popliteal artery. The purpose of this study was to determine whether drug coated balloons (DCB), interwoven stents (IWS), or plain old balloon angioplasty (POBA) would be suitable for use in distal femoropopliteal (FP) long lesions when an Eluvia stent was implanted proximal to a lesion. This was a multi-center retrospective study enrolling patients undergoing concomitant use of Eluvia with DCB, IWS or POBA for symptomatic atherosclerotic femoropopliteal disease (lesion length > 15 cm) [Rutherf...
Source: Cardiovascular Intervention and Therapeutics - April 18, 2024 Category: Cardiology Source Type: research
Is Stent Retraction to ReLieve Arterial Cerebral VaSospasm Caused by SAH (Stent-ReLACSS) Using PRELAX the Long-awaited Solution for Treatment of Posthemorrhagic Cerebral Vasospasm?
ConclusionBased on the presented data it appears that Stent-ReLACSS with pRELAX does not pose any additional risks when used to treat CVS and might be superior to SA, especially concerning mid-term and long-term efficacy. The mechanism of action may be an effect on the endothelium rather than mechanical vasodilation. As many patients with CVS are diagnosed too late, prophylactic treatment of high-risk patients (e.g., poor grade, young, female) is potentially viable. (Source: Clinical Neuroradiology)
Source: Clinical Neuroradiology - April 18, 2024 Category: Neurology Source Type: research
