Characterization and standardization of multiassay platforms for four commonly studied traumatic brain injury protein biomarkers: a TBI Endpoints Development Study
Conclusion: Due to the variability of TBI marker assay in performance and reported values, standardization strategies are recommended when comparing reported biomarker levels across assay platforms.PMID:34674546 | DOI:10.2217/bmm-2021-0284 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 22, 2021 Category: Internal Medicine Authors: George Anis Sarkis Tian Zhu Zhihui Yang Xue Li Yuan Shi Richard Rubenstein Richard A Yost Geoffrey T Manley Kevin K Wang Source Type: research

Urinary biomarkers to predict severe fluid overload after cardiac surgery: a pilot study
Conclusion: Urinary biomarkers on intensive care unit admission might be helpful to predict subsequent severe fluid overload after cardiac surgery.PMID:34672680 | DOI:10.2217/bmm-2021-0283 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 21, 2021 Category: Internal Medicine Authors: Saban Elitok Berend Isermann Sabine Westphal Prasad Devarajan Christian Albert Hermann Kuppe Martin Ernst Rinaldo Bellomo Michael Haase Anja Haase-Fielitz Source Type: research

Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with  heart failure and COVID-19
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0341. Online ahead of print.ABSTRACTAim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Selda Murat Bektas Murat Muhammet Dural Gurbet Ozge Mert Yuksel Cavusoglu Source Type: research

Serum aberrant expression of miR-24-3p and its diagnostic value in Alzheimer's disease
Conclusion: MiR-24-3p has a certain value in the diagnosis of AD and may be a potential biomarker.PMID:34668391 | DOI:10.2217/bmm-2021-0098 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Lina Liu Luran Liu Yunting Lu Tianyuan Zhang Wenting Zhao Source Type: research

Plasma endostatin correlates with hypoxia and mortality in COVID-19-associated acute respiratory failure
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0111. Online ahead of print.ABSTRACTBackground: The contribution of endothelial injury in the pathogenesis of COVID-19-associated acute respiratory distress syndrome (ARDS) and resulting respiratory failure remains unclear. Plasma endostatin, an endogenous inhibitor of angiogenesis and endothelial dysfunction is upregulated during hypoxia, inflammation and progress of pulmonary disease. Aim: To investigate if plasma endostatin is associated to hypoxia, inflammation and 30-day mortality in patients with severe COVID-19 infection. Method: Samples for blood analysis and plasma e...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Sana Asif Thoralph Ruge Anders Larsson Sara B ülow Anderberg Miklos Lipcsey Robert Fritiof Michael Hultstr öm Source Type: research

Low vitamin K status, high sclerostin and mortality risk of stable coronary heart disease patients
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0168. Online ahead of print.ABSTRACTAim: We explored whether matrix Gla protein (MGP, natural calcification inhibitor) and sclerostin (glycoprotein responsible for osteoblast differentiation) interact in terms of mortality risk in coronary patients. Methods: 945 patients after myocardial infarction and/or coronary revascularization were followed in a prospective study. All-cause death, fatal or nonfatal cardiovascular events and heart failure hospitalizations were registered. Results: Either high desphospho-uncarboxylated MGP (dp-ucMGP) or high sclerostin were independently a...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Otto Mayer Jan Bruthans Jitka Seidlerov á Julius Gel žinský Radek Ku čera Petra Karnosov á Mark éta Mateřánková Martina Rycheck á Peter Wohlfahrt Renata C ífková Jan Filipovsk ý Cees Vermeer Source Type: research

The effect of low-flux and high-flux dialysis membrane on plasma concentrations of cardiac troponin I
Conclusion: Dialysis session using low-flux membranes might increase the plasma cTnI.PMID:34668400 | DOI:10.2217/bmm-2021-0149 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Ana Šavuk Tomo Svagu ša Vladimir Trkulja Andrea Radeljak Diana Rudan Boris Kudumija Slava Doko Lucija Kova čević Mija M Pezi ć Valentina Ćorić Ivica Mati ć Ingrid Prka čin Source Type: research

Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with  heart failure and COVID-19
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0341. Online ahead of print.ABSTRACTAim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Selda Murat Bektas Murat Muhammet Dural Gurbet Ozge Mert Yuksel Cavusoglu Source Type: research

Serum aberrant expression of miR-24-3p and its diagnostic value in Alzheimer's disease
Conclusion: MiR-24-3p has a certain value in the diagnosis of AD and may be a potential biomarker.PMID:34668391 | DOI:10.2217/bmm-2021-0098 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Lina Liu Luran Liu Yunting Lu Tianyuan Zhang Wenting Zhao Source Type: research

Plasma endostatin correlates with hypoxia and mortality in COVID-19-associated acute respiratory failure
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0111. Online ahead of print.ABSTRACTBackground: The contribution of endothelial injury in the pathogenesis of COVID-19-associated acute respiratory distress syndrome (ARDS) and resulting respiratory failure remains unclear. Plasma endostatin, an endogenous inhibitor of angiogenesis and endothelial dysfunction is upregulated during hypoxia, inflammation and progress of pulmonary disease. Aim: To investigate if plasma endostatin is associated to hypoxia, inflammation and 30-day mortality in patients with severe COVID-19 infection. Method: Samples for blood analysis and plasma e...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Sana Asif Thoralph Ruge Anders Larsson Sara B ülow Anderberg Miklos Lipcsey Robert Fritiof Michael Hultstr öm Source Type: research

Low vitamin K status, high sclerostin and mortality risk of stable coronary heart disease patients
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0168. Online ahead of print.ABSTRACTAim: We explored whether matrix Gla protein (MGP, natural calcification inhibitor) and sclerostin (glycoprotein responsible for osteoblast differentiation) interact in terms of mortality risk in coronary patients. Methods: 945 patients after myocardial infarction and/or coronary revascularization were followed in a prospective study. All-cause death, fatal or nonfatal cardiovascular events and heart failure hospitalizations were registered. Results: Either high desphospho-uncarboxylated MGP (dp-ucMGP) or high sclerostin were independently a...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Otto Mayer Jan Bruthans Jitka Seidlerov á Julius Gel žinský Radek Ku čera Petra Karnosov á Mark éta Mateřánková Martina Rycheck á Peter Wohlfahrt Renata C ífková Jan Filipovsk ý Cees Vermeer Source Type: research

The effect of low-flux and high-flux dialysis membrane on plasma concentrations of cardiac troponin I
Conclusion: Dialysis session using low-flux membranes might increase the plasma cTnI.PMID:34668400 | DOI:10.2217/bmm-2021-0149 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Ana Šavuk Tomo Svagu ša Vladimir Trkulja Andrea Radeljak Diana Rudan Boris Kudumija Slava Doko Lucija Kova čević Mija M Pezi ć Valentina Ćorić Ivica Mati ć Ingrid Prka čin Source Type: research

Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with  heart failure and COVID-19
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0341. Online ahead of print.ABSTRACTAim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Selda Murat Bektas Murat Muhammet Dural Gurbet Ozge Mert Yuksel Cavusoglu Source Type: research

Serum aberrant expression of miR-24-3p and its diagnostic value in Alzheimer's disease
Conclusion: MiR-24-3p has a certain value in the diagnosis of AD and may be a potential biomarker.PMID:34668391 | DOI:10.2217/bmm-2021-0098 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Lina Liu Luran Liu Yunting Lu Tianyuan Zhang Wenting Zhao Source Type: research

Plasma endostatin correlates with hypoxia and mortality in COVID-19-associated acute respiratory failure
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0111. Online ahead of print.ABSTRACTBackground: The contribution of endothelial injury in the pathogenesis of COVID-19-associated acute respiratory distress syndrome (ARDS) and resulting respiratory failure remains unclear. Plasma endostatin, an endogenous inhibitor of angiogenesis and endothelial dysfunction is upregulated during hypoxia, inflammation and progress of pulmonary disease. Aim: To investigate if plasma endostatin is associated to hypoxia, inflammation and 30-day mortality in patients with severe COVID-19 infection. Method: Samples for blood analysis and plasma e...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Sana Asif Thoralph Ruge Anders Larsson Sara B ülow Anderberg Miklos Lipcsey Robert Fritiof Michael Hultstr öm Source Type: research

Low vitamin K status, high sclerostin and mortality risk of stable coronary heart disease patients
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0168. Online ahead of print.ABSTRACTAim: We explored whether matrix Gla protein (MGP, natural calcification inhibitor) and sclerostin (glycoprotein responsible for osteoblast differentiation) interact in terms of mortality risk in coronary patients. Methods: 945 patients after myocardial infarction and/or coronary revascularization were followed in a prospective study. All-cause death, fatal or nonfatal cardiovascular events and heart failure hospitalizations were registered. Results: Either high desphospho-uncarboxylated MGP (dp-ucMGP) or high sclerostin were independently a...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Otto Mayer Jan Bruthans Jitka Seidlerov á Julius Gel žinský Radek Ku čera Petra Karnosov á Mark éta Mateřánková Martina Rycheck á Peter Wohlfahrt Renata C ífková Jan Filipovsk ý Cees Vermeer Source Type: research

The effect of low-flux and high-flux dialysis membrane on plasma concentrations of cardiac troponin I
Conclusion: Dialysis session using low-flux membranes might increase the plasma cTnI.PMID:34668400 | DOI:10.2217/bmm-2021-0149 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Ana Šavuk Tomo Svagu ša Vladimir Trkulja Andrea Radeljak Diana Rudan Boris Kudumija Slava Doko Lucija Kova čević Mija M Pezi ć Valentina Ćorić Ivica Mati ć Ingrid Prka čin Source Type: research

Prognostic value of D-dimer/fibrinogen ratio on in-hospital outcomes of patients with  heart failure and COVID-19
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0341. Online ahead of print.ABSTRACTAim: In the present study, the relationship between D-dimer/fibrinogen ratio (DFR) and in-hospital outcomes was evaluated in patients with COVID-19 and a diagnosis of heart failure (HF). Materials & methods: In-hospital outcomes were compared in patients with high and low DFR values. Results: With regard to in-hospital outcomes, patients in the third tertile of DFR had a higher rate of mechanical ventilation, cardiogenic shock and death (p
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Selda Murat Bektas Murat Muhammet Dural Gurbet Ozge Mert Yuksel Cavusoglu Source Type: research

Serum aberrant expression of miR-24-3p and its diagnostic value in Alzheimer's disease
Conclusion: MiR-24-3p has a certain value in the diagnosis of AD and may be a potential biomarker.PMID:34668391 | DOI:10.2217/bmm-2021-0098 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Lina Liu Luran Liu Yunting Lu Tianyuan Zhang Wenting Zhao Source Type: research

Plasma endostatin correlates with hypoxia and mortality in COVID-19-associated acute respiratory failure
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0111. Online ahead of print.ABSTRACTBackground: The contribution of endothelial injury in the pathogenesis of COVID-19-associated acute respiratory distress syndrome (ARDS) and resulting respiratory failure remains unclear. Plasma endostatin, an endogenous inhibitor of angiogenesis and endothelial dysfunction is upregulated during hypoxia, inflammation and progress of pulmonary disease. Aim: To investigate if plasma endostatin is associated to hypoxia, inflammation and 30-day mortality in patients with severe COVID-19 infection. Method: Samples for blood analysis and plasma e...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Sana Asif Thoralph Ruge Anders Larsson Sara B ülow Anderberg Miklos Lipcsey Robert Fritiof Michael Hultstr öm Source Type: research

Low vitamin K status, high sclerostin and mortality risk of stable coronary heart disease patients
Biomark Med. 2021 Oct 20. doi: 10.2217/bmm-2021-0168. Online ahead of print.ABSTRACTAim: We explored whether matrix Gla protein (MGP, natural calcification inhibitor) and sclerostin (glycoprotein responsible for osteoblast differentiation) interact in terms of mortality risk in coronary patients. Methods: 945 patients after myocardial infarction and/or coronary revascularization were followed in a prospective study. All-cause death, fatal or nonfatal cardiovascular events and heart failure hospitalizations were registered. Results: Either high desphospho-uncarboxylated MGP (dp-ucMGP) or high sclerostin were independently a...
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Otto Mayer Jan Bruthans Jitka Seidlerov á Julius Gel žinský Radek Ku čera Petra Karnosov á Mark éta Mateřánková Martina Rycheck á Peter Wohlfahrt Renata C ífková Jan Filipovsk ý Cees Vermeer Source Type: research

The effect of low-flux and high-flux dialysis membrane on plasma concentrations of cardiac troponin I
Conclusion: Dialysis session using low-flux membranes might increase the plasma cTnI.PMID:34668400 | DOI:10.2217/bmm-2021-0149 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 20, 2021 Category: Internal Medicine Authors: Ana Šavuk Tomo Svagu ša Vladimir Trkulja Andrea Radeljak Diana Rudan Boris Kudumija Slava Doko Lucija Kova čević Mija M Pezi ć Valentina Ćorić Ivica Mati ć Ingrid Prka čin Source Type: research

Factors associated with baseline and serial changes in circulating NT-proBNP and high-sensitivity cardiac troponin T in a population-based cohort (Dallas Heart Study)
Biomark Med. 2021 Oct 19. doi: 10.2217/bmm-2021-0055. Online ahead of print.ABSTRACTAim: N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin T (hs-cTnT) associate with structural heart disease and heart failure risk in individuals without known cardiovascular disease (CVD). However, few data are available regarding whether factors influencing levels of these two biomarkers are similar or distinct. We performed serial measurement of NT-proBNP and hs-cTnT in a contemporary multiethnic cohort with extensive phenotyping, with the goal of identifying their respective biological determinan...
Source: Future Medicine: Biomarkers in Medicine - October 19, 2021 Category: Internal Medicine Authors: Christopher W Puleo Colby R Ayers Sonia Garg Ian J Neeland Alana A Lewis Ambarish Pandey Mark H Drazner James A de Lemos Source Type: research

Dynamic monitoring of serum ferritin as an adverse prognostic biomarker in patients with multiple myeloma
Conclusion: SF can be used as a prognostic factor at initial diagnosis and relapse in patients with MM.PMID:34651511 | DOI:10.2217/bmm-2020-0849 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yanqing Zhang Jiaqi Pan Xi Chen Lianjie Wang Liyan Chen Yaoyao Tian Wei Wang Source Type: research

Correlation of transrenal DNA with non-small-cell lung cancer in noninvasive disease monitoring
Biomark Med. 2021 Oct 15. doi: 10.2217/bmm-2020-0651. Online ahead of print.ABSTRACTBackground: The study aims to use noninvasive transrenal DNA in advanced non-small-cell lung cancer (NSCLC) patients for treatment monitoring and prognosis. Methods: Urine specimens were collected longitudinally for 103 late-stage NSCLC patients. Detection of targetable mutations in transrenal DNA was achieved by digital droplet PCR. Patients' overall survival outcomes were correlated with levels of transrenal DNA. Results: Corresponding patients' matched tumor results demonstrated concordance rate of 95.6% with transrenal DNA. A significan...
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Ziyang Zhu Fajiu Li Xiaojiang Wang Chenghong Li Qinghua Meng Chuanhai Wang Jie Huang Shi Chen Xiaomu Wu Source Type: research

Machine-learning algorithms predict breast cancer patient survival from UK Biobank whole-exome sequencing data
Conclusion: We showed that machine-learning algorithms can be used to predict overall survival in breast cancer patients from blood-based whole-exome sequencing data.PMID:34651513 | DOI:10.2217/bmm-2021-0280 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Bum-Sup Jang In Ah Kim Source Type: research

PARP1 as a prognostic biomarker for human cancers: a meta-analysis
Conclusion: Our findings confirmed that PARP1 might be a promising biomarker for prognosis in human cancers.PMID:34651514 | DOI:10.2217/bmm-2020-0891 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yan-Hua Huang Sun-Jun Yin Yuan-Yuan Gong Zhi-Ran Li Qin Yang Yu-Xin Fan Tao Zhou Rui Meng Ping Wang Gong-Hao He Source Type: research

Dynamic monitoring of serum ferritin as an adverse prognostic biomarker in patients with multiple myeloma
Conclusion: SF can be used as a prognostic factor at initial diagnosis and relapse in patients with MM.PMID:34651511 | DOI:10.2217/bmm-2020-0849 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yanqing Zhang Jiaqi Pan Xi Chen Lianjie Wang Liyan Chen Yaoyao Tian Wei Wang Source Type: research

Correlation of transrenal DNA with non-small-cell lung cancer in noninvasive disease monitoring
Biomark Med. 2021 Oct 15. doi: 10.2217/bmm-2020-0651. Online ahead of print.ABSTRACTBackground: The study aims to use noninvasive transrenal DNA in advanced non-small-cell lung cancer (NSCLC) patients for treatment monitoring and prognosis. Methods: Urine specimens were collected longitudinally for 103 late-stage NSCLC patients. Detection of targetable mutations in transrenal DNA was achieved by digital droplet PCR. Patients' overall survival outcomes were correlated with levels of transrenal DNA. Results: Corresponding patients' matched tumor results demonstrated concordance rate of 95.6% with transrenal DNA. A significan...
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Ziyang Zhu Fajiu Li Xiaojiang Wang Chenghong Li Qinghua Meng Chuanhai Wang Jie Huang Shi Chen Xiaomu Wu Source Type: research

Machine-learning algorithms predict breast cancer patient survival from UK Biobank whole-exome sequencing data
Conclusion: We showed that machine-learning algorithms can be used to predict overall survival in breast cancer patients from blood-based whole-exome sequencing data.PMID:34651513 | DOI:10.2217/bmm-2021-0280 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Bum-Sup Jang In Ah Kim Source Type: research

PARP1 as a prognostic biomarker for human cancers: a meta-analysis
Conclusion: Our findings confirmed that PARP1 might be a promising biomarker for prognosis in human cancers.PMID:34651514 | DOI:10.2217/bmm-2020-0891 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yan-Hua Huang Sun-Jun Yin Yuan-Yuan Gong Zhi-Ran Li Qin Yang Yu-Xin Fan Tao Zhou Rui Meng Ping Wang Gong-Hao He Source Type: research

Dynamic monitoring of serum ferritin as an adverse prognostic biomarker in patients with multiple myeloma
Conclusion: SF can be used as a prognostic factor at initial diagnosis and relapse in patients with MM.PMID:34651511 | DOI:10.2217/bmm-2020-0849 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yanqing Zhang Jiaqi Pan Xi Chen Lianjie Wang Liyan Chen Yaoyao Tian Wei Wang Source Type: research

Correlation of transrenal DNA with non-small-cell lung cancer in noninvasive disease monitoring
Biomark Med. 2021 Oct 15. doi: 10.2217/bmm-2020-0651. Online ahead of print.ABSTRACTBackground: The study aims to use noninvasive transrenal DNA in advanced non-small-cell lung cancer (NSCLC) patients for treatment monitoring and prognosis. Methods: Urine specimens were collected longitudinally for 103 late-stage NSCLC patients. Detection of targetable mutations in transrenal DNA was achieved by digital droplet PCR. Patients' overall survival outcomes were correlated with levels of transrenal DNA. Results: Corresponding patients' matched tumor results demonstrated concordance rate of 95.6% with transrenal DNA. A significan...
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Ziyang Zhu Fajiu Li Xiaojiang Wang Chenghong Li Qinghua Meng Chuanhai Wang Jie Huang Shi Chen Xiaomu Wu Source Type: research

Machine-learning algorithms predict breast cancer patient survival from UK Biobank whole-exome sequencing data
Conclusion: We showed that machine-learning algorithms can be used to predict overall survival in breast cancer patients from blood-based whole-exome sequencing data.PMID:34651513 | DOI:10.2217/bmm-2021-0280 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Bum-Sup Jang In Ah Kim Source Type: research

PARP1 as a prognostic biomarker for human cancers: a meta-analysis
Conclusion: Our findings confirmed that PARP1 might be a promising biomarker for prognosis in human cancers.PMID:34651514 | DOI:10.2217/bmm-2020-0891 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yan-Hua Huang Sun-Jun Yin Yuan-Yuan Gong Zhi-Ran Li Qin Yang Yu-Xin Fan Tao Zhou Rui Meng Ping Wang Gong-Hao He Source Type: research

Dynamic monitoring of serum ferritin as an adverse prognostic biomarker in patients with multiple myeloma
Conclusion: SF can be used as a prognostic factor at initial diagnosis and relapse in patients with MM.PMID:34651511 | DOI:10.2217/bmm-2020-0849 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yanqing Zhang Jiaqi Pan Xi Chen Lianjie Wang Liyan Chen Yaoyao Tian Wei Wang Source Type: research

Correlation of transrenal DNA with non-small-cell lung cancer in noninvasive disease monitoring
Biomark Med. 2021 Oct 15. doi: 10.2217/bmm-2020-0651. Online ahead of print.ABSTRACTBackground: The study aims to use noninvasive transrenal DNA in advanced non-small-cell lung cancer (NSCLC) patients for treatment monitoring and prognosis. Methods: Urine specimens were collected longitudinally for 103 late-stage NSCLC patients. Detection of targetable mutations in transrenal DNA was achieved by digital droplet PCR. Patients' overall survival outcomes were correlated with levels of transrenal DNA. Results: Corresponding patients' matched tumor results demonstrated concordance rate of 95.6% with transrenal DNA. A significan...
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Ziyang Zhu Fajiu Li Xiaojiang Wang Chenghong Li Qinghua Meng Chuanhai Wang Jie Huang Shi Chen Xiaomu Wu Source Type: research

Machine-learning algorithms predict breast cancer patient survival from UK Biobank whole-exome sequencing data
Conclusion: We showed that machine-learning algorithms can be used to predict overall survival in breast cancer patients from blood-based whole-exome sequencing data.PMID:34651513 | DOI:10.2217/bmm-2021-0280 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Bum-Sup Jang In Ah Kim Source Type: research

PARP1 as a prognostic biomarker for human cancers: a meta-analysis
Conclusion: Our findings confirmed that PARP1 might be a promising biomarker for prognosis in human cancers.PMID:34651514 | DOI:10.2217/bmm-2020-0891 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - October 15, 2021 Category: Internal Medicine Authors: Yan-Hua Huang Sun-Jun Yin Yuan-Yuan Gong Zhi-Ran Li Qin Yang Yu-Xin Fan Tao Zhou Rui Meng Ping Wang Gong-Hao He Source Type: research

Retraction: Identification of CD4 < sup > + < /sup > T-cell-derived CD161 < sup > + < /sup >  CD39 < sup > + < /sup > and CD39 < sup > + < /sup > CD73 < sup > + < /sup > microparticles as new biomarkers for rheumatoid arthritis
Biomark Med. 2021 Sep 24. doi: 10.2217/bmm-2016-0261r1. Online ahead of print.NO ABSTRACTPMID:34558295 | DOI:10.2217/bmm-2016-0261r1 (Source: Future Medicine: Biomarkers in Medicine)
Source: Future Medicine: Biomarkers in Medicine - September 24, 2021 Category: Internal Medicine Source Type: research