Chest pain, resolved. Does it need emergent cath lab activation (some controversy here)? And much much more.
In this study, the major outcomes were the same for both groups, but of 70 patients in the delayed group,4 required emergent intervention for sudden re-occlusion.  You can make your own conclusions.  I think I would want to intervene before there is risk of re-occlusion.However, one could make a reasonable argument for delaying, especially if you would need to awaken your cath team in the middle of the night.  It requires full antiplatelent and antithrombotic therapy, and, in my opinion, if you delay, you should institute continuous 12-lead ECG monitoring.  This is why:1. Why we need cont...
Source: Dr. Smith's ECG Blog - April 22, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs

Who Needs a CT Coronary Angiogram?
CT coronary angiograms are increasing in popularity as a non-invasive screening test for detecting blocks in coronary arteries. Coronary arteries are blood vessels supplying oxygenated blood to the heart. Angiograms are images of blood vessels, usually obtained by injecting medications for contrast from body structures. CT angiograms are reconstructions from multi slice CT scans following injection of contrast material into a forearm veins. Veins are blood vessels returning deoxygenated blood to the heart. CT coronary angiogram can be done as an outpatient test, in the X-ray department. As of now CT angiograms cannot repla...
Source: Cardiophile MD - April 18, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Is OMI an ECG Diagnosis?
Written by Jesse McLaren A 70 year old with prior MIs and stents to LAD and RCA presented to the emergency department with 2 weeks of increasing exertional chest pain radiating to the left arm, associated with nausea. The pain recurred at rest 90 minutes prior to presentation, felt like the patient ’s prior MIs, and was not relieved by 6 sprays of nitro. Paramedics provided another 3 sprays of nitro, and 6mg of morphine, which reduced but did not resolve the pain. What do you think of the ECG, and does it matter?There ’s normal sinus rhythm, LAFB, old anterior Q waves, and no diagnostic sign of OMI. I sent th...
Source: Dr. Smith's ECG Blog - April 18, 2024 Category: Cardiology Authors: Jesse McLaren Source Type: blogs

Know About Cardiogenic Shock
When the heart is not able to pump enough blood for the needs of the body and the blood pressure falls, it is known as cardiogenic shock. Most important cause of cardiogenic shock is a heart attack. It is more likely to occur in those who are older, having blocks in multiple blood vessels of the heart, and in those with a previous heart attack. Cardiogenic shock is a potentially life threatening condition and needs urgent treatment. Even with treatment about half of those with cardiogenic shock might die. Those with cardiogenic shock may have severe shortness of breath, weak pulse, rapid heart-beats, low blood pressure, un...
Source: Cardiophile MD - April 10, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, March 25th 2024
This study also reports the expansion of satellite cells in human muscle with CR. This finding is critical to suggest translational relevance to the rodent data observed for more than a decade. Moreover, the increased expression of the plasminogen receptor Plg-RKT observed on human satellite cells during CR provided additional support for the theory that our rodent model is relevant to human biology. « Back to Top Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length https://www.fightaging.org/archives/2024/03/interesting-insight-into-the-relationship-between-t...
Source: Fight Aging! - March 24, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Excimer Laser Coronary Angioplasty
Transcript of the video: Conventional balloon angioplasty enlarges the vessel a bit as well as plasters the plaque on to the vessel wall, while laser angioplasty is a new technique, also known as laser atherectomy, in which excimer laser, which is a monochromatic source of light, is used to vaporize the plaque or thrombus by producing heat and shock waves. The most important advantage of laser angioplasty or excimer laser angioplasty, is that you need only a standard guidwire, 0.014 inch standard guide wire, unlike the other atherectomy devices which require a bulkier guidewire. Diagrammatic representation of laser angiopl...
Source: Cardiophile MD - March 21, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Improving Stem Cell Therapies that Promote Blood Vessel Generation in Ischemic Tissue
Stem cell therapies are one of the approaches to treating progressive loss of blood flow to tissues, such as results from severe atherosclerosis, in which important blood vessels are narrowed or even blocked. Unfortunately first generation stem cell therapies are variable in outcome, cellular senescence in cell cultures prior to transplantation is poorly controlled, and the transplanted cells die quite quickly. Thus even though the benefits of treatment arise from signaling generated by transplanted cells, rather than cell integrating into tissues, there is much that can be improved. One of the ways in which researchers ar...
Source: Fight Aging! - March 20, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What is the risk of ACS after PCI in a CTO related artery ?
CTOs are opened primarily for four reasons Angina which is refractory to drugs Stress test positivity with or without angina Anxiety of having a blocked coronary artery in a self educated patient Cardiologist’s clandestine pride & pursuit* * Personal experience included Some evidence based observation Most of the studies as on today do not give survival advantage of opening a CTO.(DECISION-CTO,EURO-CTO,EXPLORE,IMPACTOR) Opening a CTO, for reasons other than angina (i.e. for relief of dyspnea or improving functional capacity) is largely conjectural and based on randomly accrued data back...
Source: Dr.S.Venkatesan MD - March 16, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized cto cto hardware cto trials jcto score open artery hypothesisacc esc aha guidelines Source Type: blogs

No, we can ’ t call OMT, as a re-vascularisation  procedure.
Hi, welcome Mr George, I just reviewed your records. You have three blocks in your arteries supplying the heart. Are they serious Doctor ? Not really, but one of them appear tight What should I do Doctor ? But, I am comfortable Doctor. You may be. But I am not .You need to undergo some re-vascularisation procedure . What do you mean by that Doctor ? It means either a percutaneous coronary intervention with a stent or CABG. Can I get my heart re-vascularised by drugs alone Doctor ? No we can’t . Hmmm , wait, we do have something called OMT/GDMT. Can you put on hold for some time Mr George, ...
Source: Dr.S.Venkatesan MD - February 25, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Why is Aspirin, everyone ’ s nemesis ?
Here is a current review on a topic, which needs some soulful Introspection For a kid, A stands for apple in kindergarten, while in the school of cardiac sciences, A would sound as Aspirin. Such is the importance of this drug, known for its obedient, predictable efficiency in the entire spectrum of CAD right from primary prevention of CAD to emergent primary angioplasty in Cath lab. Most of us will also agree, It is a work horse drug for not only for the cardiologists , but been an anchor drug in as many critical medical therapeutics, wherever platelets are to be passivated. We are well aware of molecular bas...
Source: Dr.S.Venkatesan MD - February 1, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized acc aha guidelines aspirin bias-against-aspirin dapt esc guidelines mapt Source Type: blogs

ACS management philosophy : A thought provocation
Question A cath lab is an “optional accessory” in the management of Acute coronary syndrome (ACS). True or False ? Answer “Without a CCU…you can never, treat any Acute coronary syndrome … while we can treat most ACSs successfully without a cath lab “ (If you still got the answer wrong …sorry, no comments) Best comment Accessory is ok , but it is “20% foolish” to state cath-lab is optional, it should be mandatory. (Source: Dr.S.Venkatesan MD)
Source: Dr.S.Venkatesan MD - January 19, 2024 Category: Cardiology Authors: dr s venkatesan Tags: acute coroanry syndrome acute coronary syndrome acc aha esc guidlines coronary care unit pci ptca role of cath lab in cardiology Source Type: blogs

Acute OMI or " Benign " Early Repolarization?
Written by Willy FrickA man in his 50s with a history of hypertension, dyslipidemia, type 2 diabetes mellitus, and prior inferior OMI status post DES to his proximal RCA 3 years prior presented to the emergency department at around 3 AM complaining of chest pain onset around 9 PM the evening prior. He described it as severe, sharp, and substernal with associated nausea, vomiting, chills, and diaphoresis. The following ECG was obtained. Note that the machine read is" normal sinus rhythm, normal ECG. " Cardiology over read the tracing and signed the interpretation without modification.ECG 1What do you think?The Queen of Hear...
Source: Dr. Smith's ECG Blog - December 27, 2023 Category: Cardiology Authors: Willy Frick Source Type: blogs

Occlusion myocardial infarction is a clinical diagnosis
Written by Willy Frick (@Willyhfrick).  Willy is a cardiology fellow with a keen interest in the ECG in OMI.A woman in her late 70s presented with left arm pain. The arm pain started the day prior when she was at the dentist ' s office for a root canal. Her systolic blood pressure at the dentist was over 200 mm Hg. She was given nitroglycerin which improved her blood pressure, and she completed the procedure. Her arm pain abated. The pain returned that evening and woke her from sleep. She eventually fell back asleep, and woke up feeling normal the next day (the day of presentation). After dinner the day of presentatio...
Source: Dr. Smith's ECG Blog - December 11, 2023 Category: Cardiology Authors: Willy Frick Source Type: blogs

STEMI Breakthrough: Looking beyond Primary PCI with “ Intra-coronary liquid oxygen ”
This study was sponsored by ZOLL® TherOx® . A possible deterrent is the problematic and complex concept of reperfusion Injury. The term Oxygen radicals always sounds sinister .Really I can’t understand how a cell which get injured by the lack of a a particuar gas, get damaged by the same gas .(Oxygen in liquid from might behave differently as in this study ?) I think,its all in timing of delivery of oxygen, and if we start thinking like Einstein, then ,there is nothing called time. cit0923_ft_zoll-1Download Final message Innovation and experimentation is must be allowed as liberally as possible....
Source: Dr.S.Venkatesan MD - November 25, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized Source Type: blogs

Kento Health Raises $4.1 Million CAD to Bring AI to Cardiovascular Care
Dialogue Alumni’s New Startup is Gearing up to Strike Hard in the Battle Against the Leading Cause of Death Montréal-based healthtech startup Kento Health has closed a $4.1 million CAD ($3 million USD) pre-seed financing round. The round was led by Boreal Ventures and N49P and saw participation from Broom Ventures, Graphite Ventures, and several other strategic angel investors as well as an undisclosed US-based medical institution. Kento claims it is poised to make a substantial impact in the fight against the world’s leading cause of death by using technology like artificial intelligence (AI). “This funding not...
Source: EMR and HIPAA - November 8, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alex Norman Boreal Ventures Broom Ventures David Charbonneau Dialogue Health Graphite Ventures Health IT Funding Health IT Fundings Health IT Investment Jonah Davies Kento Kento Health Max Leca Source Type: blogs