STEMI Breakthrough: Looking beyond Primary PCI with “ Intra-coronary liquid oxygen ”

This study was sponsored by ZOLL® TherOx® . A possible deterrent is the problematic and complex concept of reperfusion Injury. The term Oxygen radicals always sounds sinister .Really I can’t understand how a cell which get injured by the lack of a a particuar gas, get damaged by the same gas .(Oxygen in liquid from might behave differently as in this study ?) I think,its all in timing of delivery of oxygen, and if we start thinking like Einstein, then ,there is nothing called time. cit0923_ft_zoll-1Download Final message Innovation and experimentation is must be allowed as liberally as possible. Breakthroughs happen accidentally at any time. Systemic oxygen may be harmful, but localised delivery of O2, might exactly be the thing, the dying tissues are waiting for. Sometimes we Ignore a good concept for no reason. Bias against drug companies also can be counterproductive. Reference 1.Stone GW, Martin JL, de Boer MJ, Margheri M, Bramucci E, Blankenship JC, Metzger DC, Gibbons RJ, Lindsay BS, Weiner BH, Lansky AJ, Krucoff MW, Fahy M, Boscardin WJ; AMIHOT-II Trial Investigators. Effect of supersaturated oxygen delivery on infarct size after percutaneous coronary intervention in acute myocardial infarction. Circ Cardiovasc Interv. 2009 Oct;2(5):366-75.
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: Tags: Uncategorized Source Type: blogs