Insomnia Management: A Review and Update
J Fam Pract. 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620.ABSTRACTInsomnia is a distinct disorder that is common, yet underrecognized and undertreated in primary care. Treating insomnia has been shown to improve outcomes, including reduced risk of developing cardiovascular and mental health disorders. Insomnia is influenced by the brain's regulation of sleep and wake, which are mutually exclusive events. Insomnia should be treated as a distinct condition, even when occurring with a comorbid diagnosis such as depression or anxiety. Clinicians should implement a multimodal approach to insomnia management, including n...
Source: The Journal of Family Practice - August 7, 2023 Category: Practice Management Authors: David P Shaha Source Type: research
Insomnia Management: A Review and Update
J Fam Pract. 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620.ABSTRACTInsomnia is a distinct disorder that is common, yet underrecognized and undertreated in primary care. Treating insomnia has been shown to improve outcomes, including reduced risk of developing cardiovascular and mental health disorders. Insomnia is influenced by the brain's regulation of sleep and wake, which are mutually exclusive events. Insomnia should be treated as a distinct condition, even when occurring with a comorbid diagnosis such as depression or anxiety. Clinicians should implement a multimodal approach to insomnia management, including n...
Source: The Journal of Family Practice - August 7, 2023 Category: Practice Management Authors: David P Shaha Source Type: research
Insomnia Management: A Review and Update
J Fam Pract. 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620.ABSTRACTInsomnia is a distinct disorder that is common, yet underrecognized and undertreated in primary care. Treating insomnia has been shown to improve outcomes, including reduced risk of developing cardiovascular and mental health disorders. Insomnia is influenced by the brain's regulation of sleep and wake, which are mutually exclusive events. Insomnia should be treated as a distinct condition, even when occurring with a comorbid diagnosis such as depression or anxiety. Clinicians should implement a multimodal approach to insomnia management, including n...
Source: The Journal of Family Practice - August 7, 2023 Category: Practice Management Authors: David P Shaha Source Type: research
Pharmacology in Treatment of Patients with Disorders of Consciousness
Pharmacologic treatment of disorders of consciousness remains a critical but challenging task for clinicians. Amantadine has been shown to promote the rate of neurologic recovery for patients with traumatic disorders of consciousness when administered between 4 and 16 weeks, as demonstrated by a well-designed randomized control trial. While there are no large, randomized controlled trials to support the use of other dopaminergic medicines (bromocriptine, levodopa, apomorphine), there is a large body of literature implicating their role in improving alertness an d responsiveness in disorders of consciousness. Zolpidem can...
Source: Physical Medicine and Rehabilitation Clinics of North America - August 1, 2023 Category: Rehabilitation Authors: Michael H. Marino Source Type: research
Current Market Potential and Prospects of Copper-based Pyridine Derivatives: A Review
Curr Mol Med. 2023 Jul 26. doi: 10.2174/1566524023666230726160056. Online ahead of print.ABSTRACTNicotine, minodronic acid, nicotinamide (niacin), zolpidem, zolimidine, and other pyridine-based chemicals play vital roles in medicine and biology. Pyridine-containing drugs are widely available on the market to treat a wide range of human ailments. As a result of these advances, pyridine research is continually expanding, and there are now higher expectations for how it may aid in the treatment of numerous ailments. This evaluation incorporates data acquired from sources, like PubMed, to provide a thorough summary of the appr...
Source: Current Molecular Medicine - July 27, 2023 Category: Molecular Biology Authors: Shivani Tyagi Rakhi Mishra Rupa Mazumder Avijit Mazumder Source Type: research
Current Market Potential and Prospects of Copper-based Pyridine Derivatives: A Review
Curr Mol Med. 2023 Jul 26. doi: 10.2174/1566524023666230726160056. Online ahead of print.ABSTRACTNicotine, minodronic acid, nicotinamide (niacin), zolpidem, zolimidine, and other pyridine-based chemicals play vital roles in medicine and biology. Pyridine-containing drugs are widely available on the market to treat a wide range of human ailments. As a result of these advances, pyridine research is continually expanding, and there are now higher expectations for how it may aid in the treatment of numerous ailments. This evaluation incorporates data acquired from sources, like PubMed, to provide a thorough summary of the appr...
Source: Molecular Medicine - July 27, 2023 Category: Molecular Biology Authors: Shivani Tyagi Rakhi Mishra Rupa Mazumder Avijit Mazumder Source Type: research
Current Market Potential and Prospects of Copper-based Pyridine Derivatives: A Review
Curr Mol Med. 2023 Jul 26. doi: 10.2174/1566524023666230726160056. Online ahead of print.ABSTRACTNicotine, minodronic acid, nicotinamide (niacin), zolpidem, zolimidine, and other pyridine-based chemicals play vital roles in medicine and biology. Pyridine-containing drugs are widely available on the market to treat a wide range of human ailments. As a result of these advances, pyridine research is continually expanding, and there are now higher expectations for how it may aid in the treatment of numerous ailments. This evaluation incorporates data acquired from sources, like PubMed, to provide a thorough summary of the appr...
Source: Current Molecular Medicine - July 27, 2023 Category: Molecular Biology Authors: Shivani Tyagi Rakhi Mishra Rupa Mazumder Avijit Mazumder Source Type: research
Current Market Potential and Prospects of Copper-based Pyridine Derivatives: A Review
Curr Mol Med. 2023 Jul 26. doi: 10.2174/1566524023666230726160056. Online ahead of print.ABSTRACTNicotine, minodronic acid, nicotinamide (niacin), zolpidem, zolimidine, and other pyridine-based chemicals play vital roles in medicine and biology. Pyridine-containing drugs are widely available on the market to treat a wide range of human ailments. As a result of these advances, pyridine research is continually expanding, and there are now higher expectations for how it may aid in the treatment of numerous ailments. This evaluation incorporates data acquired from sources, like PubMed, to provide a thorough summary of the appr...
Source: Molecular Medicine - July 27, 2023 Category: Molecular Biology Authors: Shivani Tyagi Rakhi Mishra Rupa Mazumder Avijit Mazumder Source Type: research
Current Market Potential and Prospects of Copper-based Pyridine Derivatives: A Review
Curr Mol Med. 2023 Jul 26. doi: 10.2174/1566524023666230726160056. Online ahead of print.ABSTRACTNicotine, minodronic acid, nicotinamide (niacin), zolpidem, zolimidine, and other pyridine-based chemicals play vital roles in medicine and biology. Pyridine-containing drugs are widely available on the market to treat a wide range of human ailments. As a result of these advances, pyridine research is continually expanding, and there are now higher expectations for how it may aid in the treatment of numerous ailments. This evaluation incorporates data acquired from sources, like PubMed, to provide a thorough summary of the appr...
Source: Current Molecular Medicine - July 27, 2023 Category: Molecular Biology Authors: Shivani Tyagi Rakhi Mishra Rupa Mazumder Avijit Mazumder Source Type: research
Current Market Potential and Prospects of Copper-based Pyridine Derivatives: A Review
Curr Mol Med. 2023 Jul 26. doi: 10.2174/1566524023666230726160056. Online ahead of print.ABSTRACTNicotine, minodronic acid, nicotinamide (niacin), zolpidem, zolimidine, and other pyridine-based chemicals play vital roles in medicine and biology. Pyridine-containing drugs are widely available on the market to treat a wide range of human ailments. As a result of these advances, pyridine research is continually expanding, and there are now higher expectations for how it may aid in the treatment of numerous ailments. This evaluation incorporates data acquired from sources, like PubMed, to provide a thorough summary of the appr...
Source: Current Molecular Medicine - July 27, 2023 Category: Molecular Biology Authors: Shivani Tyagi Rakhi Mishra Rupa Mazumder Avijit Mazumder Source Type: research
Case report: Hyperactive delirium after a single dose of zolpidem administered additionally to psychopharmacotherapy including clozapine
The non-benzodiazepine hypnotic zolpidem is frequently administered as a short term psychopharmacotherapy for insomnia. Although it is well-established in a broad clinical routine and often well-tolerated, severe delirium and complex sleep behavior were reported in rare cases. Hereby, it remains unclear whether zolpidem's potential for delirium might be enhanced when combined with further psychopharmacotherapeutics. The present case report portrays a young male Caucasian inpatient with schizoaffective disorder, who was admitted due to severe hyperactive delirium after a single dose of zolpidem 10 mg that was administered i...
Source: Frontiers in Psychiatry - July 27, 2023 Category: Psychiatry Source Type: research
Number, Duration, and Distribution of Wake Bouts in Patients with Insomnia Disorder: Effect of Daridorexant and Zolpidem
ConclusionDaridorexant reduced the number and duration of longer wake bouts throughout the night compared with placebo, corresponding with improved daytime functioning.Clinical TrialsClinicaltrials.gov NCT02839200 (registered July 20, 2016), NCT03545191 (registered June 4, 2018). (Source: CNS Drugs)
Source: CNS Drugs - July 21, 2023 Category: Neurology Source Type: research
EEG dynamics induced by zolpidem forecast consciousness evolution in prolonged disorders of consciousness
CONCLUSIONS: Our work revealed that the specific EEG responses to zolpidem can predict consciousness recovery in PDOC patients.SIGNIFICANCE: The zolpidem-induced specific EEG responses could potentially predict the recovery of PDOC patients, which may help clinicians and patients' families in their decision-making process.PMID:37454563 | DOI:10.1016/j.clinph.2023.06.012 (Source: Clinical Neurophysiology)
Source: Clinical Neurophysiology - July 16, 2023 Category: Neurology Authors: Qiong Gao Jianmin Hao Xiaogang Kang Fang Yuan Yu Liu Rong Chen Xiuyun Liu Rui Li Wen Jiang Source Type: research
Factors affecting clinical pharmacist decision-making when reviewing and prescribing z-drugs in primary care: a qualitative interview study
ConclusionPatient factors, time pressures, ‘rule-based’ beliefs and pharmacist self-efficacy were key practice aspects which can influence the pharmacist decision-making process when reviewing or prescribing z-drugs. Pharmacists believed z-drugs should be short-term interventions for insomnia, with non-pharmacological, holistic treatment being more appropriate for long term management. (Source: International Journal of Clinical Pharmacy)
Source: International Journal of Clinical Pharmacy - July 15, 2023 Category: Drugs & Pharmacology Source Type: research
